We have biochemically treated (periodate, borohydride, neuraminidase, organic solvents) frozen sections of human pancreas and studied the reactivity of islet-cellantibody-positive human sera and monoclonal antibodies. The autoantigen of pancreatic sections has the properties ofsialic acid containing glycolipid.
“Cytoplasmic” Islet Cell Antibodies: Evidence That the Target Antigen Is a Sialoglycoconjugate
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R C Nayak, M A K Omar, A Rabizadeh, S Srikanta, G S Eisenbarth; “Cytoplasmic” Islet Cell Antibodies: Evidence That the Target Antigen Is a Sialoglycoconjugate. Diabetes 1 June 1985; 34 (6): 617–619. https://doi.org/10.2337/diab.34.6.617
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