IgG antibodies to bovine serum albumin (BSA) were measured in 91 serum samples from children 4–17 years of age with newly diagnosed insulin-dependent diabetes mellitus (IDDM). A total of 80 healthy 12-year-old children served as control subjects. BSA antibody values >3 SDs were obtained in 6 IDDM patients and 3 control subjects (P = 0.50), and values >2 SDs were obtained in 12 IDDM patients and 4 control subjects (P = 0.11). In conclusion, IgG antibodies to BSA were not significantly increased at onset of diabetes.
IgG Antibodies to Bovine Serum Albumin Are Not Increased in Children With IDDM
BSA, bovine serum albumin; CV, coefficient of variation; HRP, horseradish peroxidase; IDDM, insulin-dependent diabetes mellitus; OD, optical density; OPD, o-phenylenediamine dichloride; PBS, phosphate-buffered saline.
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Sten-A Ivarsson, Majvi U L Månsson, Irene L Jakobsson; IgG Antibodies to Bovine Serum Albumin Are Not Increased in Children With IDDM. Diabetes 1 November 1995; 44 (11): 1349–1350. https://doi.org/10.2337/diab.44.11.1349
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