Achenbach P, Warncke K, Reiter J, Naserke HE, Williams AJK, Bingley PJ, Bonifacio E, Ziegler A-G: Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. Diabetes 53:384–392, 2004

In Fig. 4 of the above-listed article, three column heads (“A. Total cohort,” “B. Single antibody,” and “C. Multiple antibodies”) were inadvertently deleted. The correct Fig. 4 appears on the following page.

FIG. 4.

The cumulative risk of diabetes in autoantibody-positive relatives classified on the basis of islet autoantibody characteristics. Stratification is shown for the total cohort (A), for the 100 relatives with one islet autoantibody (B), and for the 80 relatives with two or more islet autoantibodies (C). Model 1 shows stratification of relatives by the number of islet autoantibodies (A = one autoantibody, B = any two autoantibodies, C = all three autoantibodies). Model 2 shows stratification of relatives by their autoantibody titer and subclass (A = none, B = one, C = two, and D = all three of high titer IA-2A, positivity for IgG2 or IgG4 IA-2A, and positivity for IgG2, IgG3, or IgG4 IAA). Model 3 shows stratification of relatives by their autoantibody titer (A = none, B = one, C = both of high titer IA-2A or high titer IAA). Model 4 shows stratification of relatives by their IA-2A and IA-2β autoantibody status (A = IA-2A negative, B = IA-2A positive/IA-2β autoantibody negative, C = IA-2β autoantibody positive).

FIG. 4.

The cumulative risk of diabetes in autoantibody-positive relatives classified on the basis of islet autoantibody characteristics. Stratification is shown for the total cohort (A), for the 100 relatives with one islet autoantibody (B), and for the 80 relatives with two or more islet autoantibodies (C). Model 1 shows stratification of relatives by the number of islet autoantibodies (A = one autoantibody, B = any two autoantibodies, C = all three autoantibodies). Model 2 shows stratification of relatives by their autoantibody titer and subclass (A = none, B = one, C = two, and D = all three of high titer IA-2A, positivity for IgG2 or IgG4 IA-2A, and positivity for IgG2, IgG3, or IgG4 IAA). Model 3 shows stratification of relatives by their autoantibody titer (A = none, B = one, C = both of high titer IA-2A or high titer IAA). Model 4 shows stratification of relatives by their IA-2A and IA-2β autoantibody status (A = IA-2A negative, B = IA-2A positive/IA-2β autoantibody negative, C = IA-2β autoantibody positive).

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