Clegg DJ, Brown LM, Zigman JM, Kemp CJ, Strader AD, Benoit SC, Woods SC, Mangiaracina M, Geary N: Estradiol-dependent decrease in the orexigenic potency of ghrelin in female rats. Diabetes 56:1051–1058, 2007

In Table 2 of the above-listed article, the two column headings “Ghrelin” should be “Saline”, and the two column headings “Saline” should be “Ghrelin”. The correct table appears below.

TABLE 2

Effects of intraperitoneal injection of 6.0 nmol ghrelin on spontaneous feeding parameters in estradiol-treated and vehicle-treated ovariectomized rats

Vehicle treated
Estradiol treated
Saline (n = 8)Ghrelin (n = 8)Saline (n = 8)Ghrelin (n = 8)
M1 latency (min) 28.8 ± 15.0 1.8 ± 1.2* 16.2 ± 8.4 19.2 ± 5.3 
M1 size (g) 1.6 ± 0.3 1.2 ± 0.2 0.6 ± 0.2 0.7 ± 0.2 
M1–2 IMI (min) 158 ± 20 115 ± 30 60 ± 17 52 ± 14 
M2 size (g) 2.0 ± 0.7 1.8 ± 0.7 0.9 ± 0.3 1.0 ± 0.4 
2-h food intake (g) 1.6 ± 0.4 2.5 ± 0.4* 1.5 ± 0.3 1.4 ± 0.2 
2-h meal no. 1.0 ± 0.3 1.6 ± 0.2 2.0 ± 0.4 2.0 ± 0.3 
Vehicle treated
Estradiol treated
Saline (n = 8)Ghrelin (n = 8)Saline (n = 8)Ghrelin (n = 8)
M1 latency (min) 28.8 ± 15.0 1.8 ± 1.2* 16.2 ± 8.4 19.2 ± 5.3 
M1 size (g) 1.6 ± 0.3 1.2 ± 0.2 0.6 ± 0.2 0.7 ± 0.2 
M1–2 IMI (min) 158 ± 20 115 ± 30 60 ± 17 52 ± 14 
M2 size (g) 2.0 ± 0.7 1.8 ± 0.7 0.9 ± 0.3 1.0 ± 0.4 
2-h food intake (g) 1.6 ± 0.4 2.5 ± 0.4* 1.5 ± 0.3 1.4 ± 0.2 
2-h meal no. 1.0 ± 0.3 1.6 ± 0.2 2.0 ± 0.4 2.0 ± 0.3 

Data are means ± SE. M1 latency is the latency to the onset of the first nocturnal meal; M1 size and M2 size are the sizes of the first and second nocturnal meals, respectively; M1–2 IMI is the interval between these meals; 2-h food intake (g) is the cumulative food intake during the first 2 h of the dark phase; and 2-h meal no. is the number of meals begun during these 2 h. ANOVA revealed a significant interaction (estradiol × ghrelin) effect for M1 latency (F1,26 = 4.92); a significant main effect of ghrelin for 2-h food intake (F1,26 = 3.57); and significant main effects of estradiol for M1 size (F1,26 = 10.54), M1–2 IMI (F1,26 = 12.38), M2 size (F1,26 = 8.35), and 2-h meal no. (F1,26 = 6.87).

*

Significant difference between ghrelin and saline injection values in vehicle-treated rats (Bonferroni test, P < 0.05);

significant difference between saline values in vehicle-treated and in estradiol-treated rats (Bonferroni test, P < 0.05).