Nair KS, Bigelow ML, Asmann YW, Chow LS, Coenen-Schimke JM, KLaus KA, Guo Z-K, Sreekumar R, Irving BA: Asian Indians have enhanced skeletal muscle mitochondrial capacity to product ATP in association with severe insulin resistance. Diabetes 57:1166–1175, 2008

In the above article, Table 3 (p. 1172) contains an error; the headings for columns 3 and 4 have been reversed. Column 3 should read “Nondiabetic European Americans” and not “Nondiabetic Asian Indians.” Column 4 should read “Nondiabetic Asian Indians” and not “Nondiabetic European Americans.” The correct table appears below. The online version reflects these changes.

TABLE 3

Genes involved in OXPHOS and citrate cycle, the two pathways that were upregulated in nondiabetic Asian Indians compared with nondiabetic European Americans

Probe setNondiabetic European AmericansNondiabetic Asian IndiansNondiabetic Asian Indians/nondiabetic European AmericansPAccessionGene name
Oxidative phosphorylation, P = 0.013        
    NDUFB4 218226_s_at 7659.66 8172.12 1.067 0.0151 NM_004547 NADH dehydrogenase (ubiquinone) 1 β subcomplex 4, 
    COX8A 201119_s_at 4522.81 5004.64 1.107 0.0259 NM_004074 Cytochrome c oxidase subunit 8A (ubiquitous) 
    COX11 239760_at 95.54 103.71 1.085 0.0307 AI198212 COX11 homolog 
    COX5A 229426_at 127.38 152.44 1.197 0.0354 BF196691 Cytochrome c oxidase subunit Va 
    COX7C 213846_at 2179.92 2314.60 1.062 0.0416 AA382702 Cytochrome c oxidase subunit VIIc 
    ATP5G3 228168_at 321.71 357.21 1.110 0.0472 AU153583 ATP synthase, H + transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 
    NDUFAB1 202077_at 3916.67 4256.75 1.087 0.0478 NM_005003 NADH dehydrogenase (ubiquinone) 1, α/β subcomplex, 1, 
Citrate cycle, P = 0.015        
    SUCLA2 202930_s_at 1874.18 1999.18 1.067 0.0442 NM_003850 Succinate-CoA ligase, ADP-forming, β-subunit 
    IDH3G 202471_s_at 610.71 663.92 1.087 0.0454 NM_004135 Isocitrate dehydrogenase 3 (NAD+)-γ 
    ATP5G3 228168_at 321.71 357.21 1.110 0.0472 AU153583 ATP synthase, H + transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 
Probe setNondiabetic European AmericansNondiabetic Asian IndiansNondiabetic Asian Indians/nondiabetic European AmericansPAccessionGene name
Oxidative phosphorylation, P = 0.013        
    NDUFB4 218226_s_at 7659.66 8172.12 1.067 0.0151 NM_004547 NADH dehydrogenase (ubiquinone) 1 β subcomplex 4, 
    COX8A 201119_s_at 4522.81 5004.64 1.107 0.0259 NM_004074 Cytochrome c oxidase subunit 8A (ubiquitous) 
    COX11 239760_at 95.54 103.71 1.085 0.0307 AI198212 COX11 homolog 
    COX5A 229426_at 127.38 152.44 1.197 0.0354 BF196691 Cytochrome c oxidase subunit Va 
    COX7C 213846_at 2179.92 2314.60 1.062 0.0416 AA382702 Cytochrome c oxidase subunit VIIc 
    ATP5G3 228168_at 321.71 357.21 1.110 0.0472 AU153583 ATP synthase, H + transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 
    NDUFAB1 202077_at 3916.67 4256.75 1.087 0.0478 NM_005003 NADH dehydrogenase (ubiquinone) 1, α/β subcomplex, 1, 
Citrate cycle, P = 0.015        
    SUCLA2 202930_s_at 1874.18 1999.18 1.067 0.0442 NM_003850 Succinate-CoA ligase, ADP-forming, β-subunit 
    IDH3G 202471_s_at 610.71 663.92 1.087 0.0454 NM_004135 Isocitrate dehydrogenase 3 (NAD+)-γ 
    ATP5G3 228168_at 321.71 357.21 1.110 0.0472 AU153583 ATP synthase, H + transporting, mitochondrial F0 complex, subunit C3 (subunit 9) 

P values associated with each pathway were calculated by IPA. P values associated with each gene were calculated using paired t test.

View Large
View Original Article
DIABETES
2009