Background: The Centers for Medicare and Medicaid (CMS) Hospital Readmissions Reduction Program (HRRP) aims to reduce 30-day readmission rates for patients with acute myocardial infarction, heart failure, pneumonia, chronic obstructive pulmonary disease and hip/knee arthroplasty. The impact of hyperglycemia on readmission rates for these diagnoses is not known.

Methods: We analyzed 30-day readmission rates for patients discharged from Florida Hospital Orlando with CMS HRRP diagnoses from July 1, 2014 through June 30, 2017. Subjects were grouped according to eligibility (2 point-of-care glucoses within 24 hours) for our glycemic monitoring program (GMP) or not (non-GMP). The GMP group was further divided into controlled (C-GMP, mean blood glucose during hospitalization 70-180 mg/dL) and hyperglycemic (H-GMP, mean blood glucose > 180 mg/dL) groups.

Results: The GMP group had significantly higher readmission rates than the non-GMP group, as did the H-GMP group relative to the C-GMP group (Table). These differences remained significant after adjusting for difference in age, sex, diagnosis, case mix index and other factors in logistic regression analyses.

Conclusion: Hyperglycemic patients discharged with a CMS HRRP diagnosis have higher 30-day readmission rates. Strategies to prevent readmission should target glycemic control during and after hospitalization.

     
Variable Non-GMP GMP C-GMP H-GMP 
17675 17008 11120 5888 
Female % 53.9% 49.8% 49.7% 49.9% 
White % 78.5% 71.8% 71.0% 73.3% 
Age (years) 67 68 69 67 
Weight (kg) 80.2 88 85.5 92.7 
Case Mix Index 1.49 2.07 2.31 1.61 
30-Day Readmission Rate (%) 14.4 21.5** 21.1 22.3*  
     
Variable Non-GMP GMP C-GMP H-GMP 
17675 17008 11120 5888 
Female % 53.9% 49.8% 49.7% 49.9% 
White % 78.5% 71.8% 71.0% 73.3% 
Age (years) 67 68 69 67 
Weight (kg) 80.2 88 85.5 92.7 
Case Mix Index 1.49 2.07 2.31 1.61 
30-Day Readmission Rate (%) 14.4 21.5** 21.1 22.3*  

* P < 0.05, ** P < 0.01 in risk-adjusted logistic regression analyses.

Disclosure

M. Gaines: None. R.E. Pratley: Other Relationship; Self; AstraZeneca, Boehringer Ingelheim Pharmaceuticals, Inc., Eisai Inc., GlaxoSmithKline plc., Janssen Pharmaceuticals, Inc., Lexicon Pharmaceuticals, Inc., Ligand Pharmaceuticals, Inc., Eli Lilly and Company, Merck & Co., Inc., Novo Nordisk Inc., Pfizer Inc., Sanofi-Aventis, Takeda Development Center Americas, Inc..

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