Background: 77% of people with diabetes have insomnia. Sleep disturbance results in impaired glucose control in healthy individuals or worsens glucose control in people with diabetes. Short-term sleep studies (1-6 weeks) improved glucose control and insulin resistance in obese “healthy” individuals. Few studies have tested the hypothesis that improving sleep quality will improve glucose control. Exercise has been proven to help both sleep and glucose control. We wanted to test, in this abstract, the impact of improving sleep with exercise.

Methods: We recommend aerobic exercise 10 minutes after each meal (HIIT) to all our patients, but not all adhere for a variety of reasons. We also advise balance and stretch.We compared 50 non-adherent type 2 patients to a matched exercise-adherent patients. We quantified feeling of well being, shortening latency of sleep onset, and sleep duration extension. We measured their glucose control with AM insulin/glucose ratio, HgA1c, and in-target glucose when CGMS was available (12 patients). All patients followed our standard diabetes treatment protocol for type 2.

Results: At 12 months, adhering to exercise improved the feeling of well being in 68%, sleep hygiene in 66% of patients; Sleep increased by 28 minutes, and sleep onset latency decreased by 8 minutes. Insulin/glucose ratio was 16/133=0.12, HgA1c 7.1%, HgA1c<7 in 69%, and in-target glucose in 74% on CGMS (7 patients). Non-adherent had feeling of well being in 45%, sleep hygiene in 14%; with sleep increasing by 4 minutes, and sleep onset latency decreased by 2 minutes. Insulin/Glucose ratio was 38/174=0.21, HgA1c 7.9%, HgA1c< 7 in 50%, and in-target-glucose in 54% on CGMS (5 patients.) diabetes medications used were 3 in both groups. Percentage needing basal insulin at the end was 8% in the exercise group, 21% in the non-adherent group.

Conclusion: Exercise Improved sleep and insulin resistance with improved glucose control. However, what is the contribution of each factor will need further study.

Disclosure

S. Sakkal: None.

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