The aim of this study was to analyze the relationship between BMI percentile and liver size and to predict the probabilities of fatty liver and hepatomegaly for overweight and obese boys and girls. 1161 records from children visiting a South Texas pediatric clinic from 2003 to 2018 were assessed. Ultrasonography was requested for patients whenever the patient was gaining excessive weight and the readings for alkaline phosphatase levels were 2 SD above the normal population or when liver enzymes were elevated, SGOT above 50/46, SGPT above 47/41, and GGT above 32/28 for boys and girls respectively. The data analysis was processed under TAMIU IRB approval #2012-01-13. The data was analyzed using logistic regression. The results were as follows. a) Boys and girls logistic regression of BMI percentile vs. Fatty Liver (n=1161, a=-11.83, Wald=49.01, df=1, p<0.05; b=0.12, Wald=43.39, df=1, p <0 .05), b) boys and girls logistic regression of BMI Percentile vs. Hepatomegaly (n=1161, a=-9.42, Wald=33.47, df=1, p<0.05; b=.085, Wald=25.73, df=1, p<0.05), c) girls logistic regression of BMI percentile vs. fatty Liver (n=450, a=-8.10, Wald=17.88, df=1, p<0.05; b=.07, Wald=13.53, df=1, p<0.05) d) girls logistic regression of BMI percentile vs. Hepatomegaly (n=450, a=-5.67, Wald=12.04, df=1, p<0.05; b=0.041, Wald=5.65, df=1, p<0.05) e) boys, Logistic regression of BMI percentile vs. Fatty Liver (n=840, a=-22.98, Wald=51.27, df=1, p<0.05; b=.23, Wald=50.58, df=1, p<0.05), f) boys logistic regression of BMI percentile vs. Hepatomegaly (n=840, a=-16.58, Wald=31.79, df=1, p <0 .05; b=.16, Wald 29.43, df=1, p<0.05). A cubic curve was also fitted between liver size and BMI percentile for each group. The results of the analysis support that the probability of fatty liver and hepatomegaly increase exponentially as BMI percentile increases, there is also a positive relationship between liver size and BMI percentile.
F.G. Quintana: None. F.J. Cervantes-Gonzalez: None. H. Wang: None.
