High prevalence rates of type 2 diabetes (T2DM) have been reported both in stable coronary artery disease (CAD) and in heart failure (HF) patients, but data directly comparing T2DM prevalence between these patient populations are not available. Here, we therefore aimed at comparing the prevalence of T2DM and of prediabetes in 195 patients with angiographically proven stable CAD who had no history, signs or symptoms of heart failure, and in 183 patients with a diagnosis of HF according to current European Society of Cardiology criteria. Using ADA criteria for the diagnosis of diabetes, T2DM prevalence was significantly higher in HF than in CAD patients (48.6% vs. 22.6%; p<0.001). Also, the proportion of patients reporting a history of diabetes was significantly higher in HF than in CAD patients (37.7% vs. 16.9%; p<0.001). HF remained associated with a higher prevalence of T2DM after multivariate adjustment (OR 2.89 [1.77-4.72]; p<0.001). In contrast, among the patients who did not have diabetes, the prevalence of prediabetes (FPG 100-125 mg/dl or HbA1c 5.7-6.5%) was similar in HF as in CAD patients (66.0 vs. 62.3% =0.558). We conclude that the prevalence of T2DM is even higher in patients with HF than in patients with stable CAD.
C.H. Saely: None. A. Vonbank: None. C. Heinzle: None. D. Zanolin-Purin: None. B. Larcher: None. A. Mader: None. S. Sternbauer: None. A. Said: None. A. Leiherer: None. A. Muendlein: None. H. Drexel: None.