Aim: To investigate the effect of body mass index (BMI) on the current control of HbA1c (A), blood pressure (B) and cholesterol(C) in patients with type 2 diabetes (T2D) from Tibet based on electronic medical records.
Methods: Patients aged 18-79 years with T2D documented from 2014 to 2018 were enrolled in this study. Control criteria were defined base on the 2017 Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes: HbA1c < 7.0%, blood pressure < 130/80mmHg and low-density lipoprotein-Cholesterol (LDL-C) < 1.8 mmol/L with coronary heart disease (CHD) and 2.6 mmol/L without CHD. Patients were divided into three groups according to BMI. One-way ANOVA and Chi-square tests were used to compare differences among groups.
Results: A total of 1999 patients were included in the study. The mean (SD) age was 55.2 (10.5) years. The median diabetic duration was 7.0 (range: 0.1-32) years and 879 (43.9%) patients were female. Among the three groups, patients with obesity had the worst metabolic profile with the highest systolic blood pressure, diastolic blood pressure and LDL-C. The achievement of ABC control has worsened in parallel with increasing BMI (Table).
Conclusions: Higher BMI was associated with lower ABC control of diabetes. More intensive weight management is warranted in this population.
Z. Chenghui: None. L. Mingxia: None. W. Suyuan: None. W. Yunhong: None.