Real-world data gathered from flash glucose monitoring (FreeStyle LibreTM system) can be used to examine the impact of exercise on time in hypoglycemia, euglycemia, and hyperglycemia. De-identified data from 623 users who recorded 29,280 exercise notes were analyzed, all having notes spanning at least 10 days and more than 25% of days with notes. Glucose time in ranges during night time (11P-8A) and fasting levels (7A-8A) following exercise days and non-exercise days were evaluated. Nights following exercise had an average of 119.2 min/night above 180 mg/dL vs. 137.0 min/night without exercise (p < .001), a difference of 17.8 min/night. There was a median difference of 11.3 fewer minutes in hyperglycemia on exercise nights, with minimal increase in time in hypoglycemia (1.2 min). Days with exercise had an average fasting glucose the next day of 137 + 59 mg/dL compared to fasting levels of 140 + 59 mg/dL without (p < .001). More exercise days had fasting glucose below 70 mg/dL (8.2% vs. 6.4%), but fewer were above 180 mg/dL (19.5% vs. 25.4%). While days with exercise are associated with increased time in hypoglycemia, users saw a greater reduction in hyperglycemia. Flash glucose monitoring can help identify pre-exercise levels and trends which can be used to assist patients in improving time-in-range without increasing nighttime hypoglycemia.

K. Covington: Employee; Self; Abbott Laboratories. S. Jangam: Employee; Self; Abbott Laboratories. Employee; Spouse/Partner; Abbott Laboratories. T. Dunn: Employee; Self; Abbott Laboratories.


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