Evidence suggests multicomponent interventions are essential to improve outcomes in minority groups. This RCT tested a multicomponent intervention (TIDES) including diabetes education and skills training by telephone and a telehealth system to monitor glycemic and blood pressure control in African Americans (AA) with poorly controlled type 2 diabetes. Two hundred AA with HbA1c >= 8 were randomized to TIDES or usual care with primary outcome HbA1c at 12-months in the intent to treat population. Baseline adjusted random intercept model evaluated reduction in HbA1c for TIDES compared to usual care. Per protocol samples and baseline adjusted marginal models were used as sensitivity analyses. Study maintained a 90% retention rate at 12-months. HbA1c at 3 months was marginally statistically significantly lower compared to usual care (p=0.06), however, at 12-months there was no statistically significant difference (p=0.67). See Figure 1. Per protocol samples and marginal models showed similar results. Results from a multicomponent RCT found a more immediate drop in HbA1c during the intervention period compared to usual care, but no significant differences at 12-months. Possible co-interventions occurring in the primary care clinic at the time of the study and low intensity booster sessions may explain results and have implications for future diabetes education trials.
L.E. Egede: None. R.G. Knapp: None. R.J. Walker: None. E. Garacci: None. J.S. Williams: None.
National Institutes of Health (R01DK098529)