Purpose: The purpose is to determine whether dosing compliance of person with hypertension(HT) or DM is related to the occurrence of AMI, stroke, and CRF.

Method: Since Korea’s health insurance is social insurance for all citizens and is operated by a separate act, there are data that claim the medical expenses of all citizens. This study uses the full medical expenses claims data of all citizens. As of 2011, all persons with HT or DM were enrolled in the year, and a retrospective cohort data was added to follow-up by 2018, adding new dosing patients each year. Since 2016, complications have been observed by year, and previous occurrences were excluded from the study. For those who took medications from 2011, we calculated the annual compliance rate of the medications up to the previous year of occurrence, and excluded those who are less than 3 years before 2018. By the age group, the annual incidence of 2016-2018 according to complications was calculated according to the average dose compliance rate and the ratio of the odds of complications among those in the 1/5 quintile and the odds of complications among others were analyzed by year.

Result: HT or DM medication compliance rates were highly associated with all complications in their 30s and 40s. Above 70 years of age was associated with stroke. In the fifties and sixties, DM or HT compliance were closely related to all complications, except that DM compliance was not associated with AMI.

Discussion: It is important for persons with HT or DM in their 30s and 40s to increase their dosing compliance to minimize their complications occurrence. It is necessary to thoroughly monitor DM compliance because this is highly related to the occurrence of the most expensive CRF. In the 50s and 60s, HT and DM compliance are closely related to the occurrence of all complications, which can significantly reduce future costs through thorough dosing of population.


K. Chun: None.

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