1021-P: Mortality and Length of Hospitalisation amongst Diabetic and Nondiabetic COVID-19 Critical Patients: A Retrospective Cohort Study

Aim: To determine the rate of mortality in critically ill COVID-19 positive diabetic patients and association with mortality and length of hospitalization.

Methods: Retrospective Cohort Study done at Nalanda Medical College and Hospital in 670 patients. Critically ill COVID-19 positive (RT-PCR proven) (>= 18yrs), either gender, attending MICU, NMCH Patna included in the study.

Results: The mortality rate of patients was 31% where as patients aged above 40 yrs were having significantly higher odds [OR(95% CL)=5.64 (1.56-20.43)] of mortality Increasing age by 10 years showed significantly higher odds [OR(95%CL)= 1.55 (1.15-2.07)] of mortality. An Insignificant association was found between diabetes and mortality in patients. The length of hospitalization in diabetic patients was higher [median =10(6,16)] than non- diabetic patients [median=7(2,12)] (p=0.036). The mean age of patients in MICU, NMCH was 51 years with 71 % patients aged more than 40 yrs. The patients had a male predominance 31 % patients were Diabetic. 106 patients were diagnosed as T2DM patients after their MICU admission. 29 % patients were Hypertensive and 23 % patients had both T2DM and HTN, 74 % patients had shortness of breath as C/F whereas only 58% patients had fever, RBS level on admission had no significant association [OR(95%CL)=0.882(0.730-1.067)] with mortality Glycemic variability had no significant association [OR(95%CL)=1.000(0.925-1.082)] with duration of hospitalization. A statistically significant association was seen between T2DM and HTN (p=0.01) in COVID-19 patients. A significant (p=0.008) proportion (90.3%) of diabetic patients were aged above 40 years as compared to nondiabetic patients.

Conclusion: COVID-19 patients attending NMCH patna have male preponderance. With increasing age, mortality increases in COVID-19 critically ill patients. Diabetes does not increase mortality in COVID-19 patients but increases the length Of hospitalization.