1024-P: Association, Prevalence, and Occurrence of Depression and Anxiety in Indian T2DM Patients Free

Background: Depression is found to be common among patients with diabetes and it is associated with poor outcomes in disease control. Mani objective of the study was to study the prevalence and occurrence of depression and anxiety in patients of type 2 diabetes mellitus (T2DM).

Materials:115 adults with T2DM without prior diagnosis of depression and 115 matched controls were evaluated. Sociodemographic and relevant clinical variables were collected. They were evaluated for depression and anxiety using Hamilton Depression Rating Scale and Hamilton Anxiety Rating Scale respectively.

Results: Significantly larger proportion of diabetic patients had depression [32 (27.8%) vs. 11 (9.57%), P = 0.005), anxiety (38 (33%) vs. 16 (13.9%, P = 0.005) and comorbid depression and anxiety (28 (24.3%) vs. 10 (8.7%), P = 0.005) as compared to healthy controls. The prevalence rate of depression was higher in age between 41 and 60 years (18.8% vs. 7.6%, respectively) in diabetic and healthy control group. Diabetic women had higher depression (21.2% vs. 8.7%) and anxiety (18.8% vs. 9.7%) than men. Depression was found significantly associated with retinopathy 28.6% (p=0.005), nephropathy 16.3% (p=0.005) and ischemic heart disease (IHD) 17.2% (p=0.005) in the present study. Comorbid depression and anxiety was significantly associated with age (40-60 years), obesity (BMI ≥ 25 kg/m2), poor glycemic control (≥7.5%), insulin therapy, nephropathy, neuropathy, and IHD but no significant association was found with education level.

Conclusion: This study found a high proportion of depression and anxiety among patients with T2DM. Public health measures are required to create more awareness for managing depression in diabetes.