Visual Abstract
Real-time continuous glucose monitoring (CGM) systems with threshold alerts can disencumber users by automatically warning of out-of-range glucose values. We examined correlations between time in range (TIR; 70-180 mg/dL), hyperglycemia alert use, and screen view frequency in a large real-world cohort. Anonymized data uploaded in 2020 by 19,367 US-based users of the G6 CGM System (Dexcom, Inc., San Diego, CA) were assessed. Data from users with >70% device utilization and validated alert settings were included. Users were stratified by screen view frequency and hyperglycemia alert use. Panel A shows TIR vs. screen view frequency for 3 cohorts defined as having the hyperglycemia alert always, sometimes, or never on. Compared to non-use, consistent use of the hyperglycemia alert corresponded to a ~5.5% higher TIR. By contrast, screen view frequency was weakly associated with increased TIR, likely because the trend screen must be accessed to silence the alert. Panel B shows the moderate inverse correlation between TIR and hyperglycemia alert setting. Automated hyperglycemia alerts may motivate appropriate treatment decisions without requiring constant scrutiny of the CGM trend screen. Lowering the hyperglycemia alert threshold may be an appropriate strategy for patients wishing to improve their TIR.
R. Dowd: Employee; Self; Dexcom, Inc. M. Derdzinski: Employee; Self; Dexcom, Inc. S. Puhr: Employee; Self; Dexcom, Inc. J. Welsh: Employee; Self; Dexcom, Inc.
