Introduction: Individuals with prediabetes (preDM) are at increased risk of developing type 2 diabetes (T2DM) and cardiovascular disease. We know little about the risk perception and lifestyle behaviors of young adults with preDM.

Methods: This nationally representative cross-sectional analysis of 2005-2018 National Health and Nutrition Examination Survey data was conducted on nonpregnant young adults (aged - 34) . PreDM and Diabetes (DM) were based on fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) definitions recommended by the American Diabetes Association. We used fasting sample weight to generate nationally representative estimates. Measures also include sociodemographic, lifestyle behaviors (diet, physical activity, and sleep) , awareness, and perceived risk for diabetes or preDM. Analyses were accounted for the complex sample design and performed using Stata 17.

Results: Overall, among 4272 young adults, the weighted prevalence of PreDM and DM were 26% and 2.6%, respectively. There was a significant difference (p<0.001) in the awareness of their disease condition between individuals with preDM (3.7%) and those with DM (13.2%) . The multivariable logistic regression model found that women were less likely to have preDM than men. Obese subjects were more likely (OR=3.19, 95%CI 2.39 - 4.27) to have preDM. College education, higher income, and physical activity (600 -1200 MET minutes/week) were protective factors against preDM. Long sleep duration (>=9 hours per day) is associated with a 56% increased risk for prediabetes (95%CI 1.02 - 2.39) .

Conclusions: The high prevalence of preDM in young adults reinforces the critical need for effective public health strategies that promote lifestyle behaviors, including physical activity, and improve sleep quality.


A.Yan: None. J.J.Wang: None. Z.Shi: None.

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