The real-world weight loss effectiveness of GLP-1RAs have not been well described. We conducted a cohort study using EHR data from an integrated healthcare system based in PA. Non-pregnant adults first dispensed a GLP-1RA between 20 and 2018 were eligible. We excluded those without:
1) at least 72 weeks of continuous enrollment after the first dispense date,
2) at least 1 year of baseline enrollment data, and
3) at least one valid weight measurement within the 8 wks before the dispense date and at least one weight measure during follow-up.
J.Luo: None. I.Shu: None. M.T.Korytkowski: None. D.A.Rometo: Advisory Panel; Nestlé Health Science. J.Arnold: None. G.E.White: None.