Background: COVID-increases risk of DKA and poor outcomes in patients with diabetes.

Methods: A retrospective review was conducted of 4,959 DKA admissions from 1/1/2019-12/31/2021 at our hospital system. EHR data was collected on consecutive admissions coded with DKA for clinical characteristics, hospital outcomes of length of stay (LOS) , 30day readmission (30d RADM) and mortality. Data was analyzed for differences stratified by year 20vs. 2020 and 2021, and by COVID-infection.

Results: Compared to 2019, patients in 2020 were older, more Hispanic and had CHF. Compared to 2019, patients in 2021 had less HTN and kidney disease but similar rates of CHF; Table 1. Mortality and LOS were higher for 2020 and 2021 while 30d RADM was lower; Table 2.

Conclusion: Despite advancements in COVID-treatments, DKA patients have progressively poorer outcomes.

Disclosure

A.Kansara: None. D.T.Nguyen: None. S.L.Yarlagadda: None. E.Graviss: None. A.R.Sadhu: Advisory Panel; Abbott Diagnostics.

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