Each month, the Diabetes editorial team chooses a single paper to be designated the Paper of the Month, which is then made available for free online and added to an exclusive collection (https://diabetesjournals.org/collection/1619/Diabetes-Paper-of-the-Month). Congratulations to the 2023 winners!
David A. D’Alessio, MD
Editor in Chief, Diabetes
January
Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy
Caleigh Mandel-Brehm, Sara E. Vazquez, Christopher Liverman, Mickie Cheng, Zoe Quandt, Andrew F. Kung, Audrey Parent, Brenda Miao, Emmanuel Disse, Christine Cugnet-Anceau, Stéphane Dalle, Elizaveta Orlova, Elena Frolova, Diana Alba, Aaron Michels, Bergithe E. Oftedal, Michail S. Lionakis, Eystein S. Husebye, Anil K. Agarwal, Xilong Li, Chengsong Zhu, Quan Li, Elif Oral, Rebecca Brown, Mark S. Anderson, Abhimanyu Garg, and Joseph L. DeRisi
February
Prostaglandin PGE2 Receptor EP4 Regulates Microglial Phagocytosis and Increases Susceptibility to Diet-Induced Obesity
Anzela Niraula, Rachael D. Fasnacht, Kelly M. Ness, Jeremy M. Frey, Sophia A. Cuschieri, Mauricio D. Dorfman, and Joshua P. Thaler
March
The Importance of Endogenously Secreted GLP-1 and GIP for Postprandial Glucose Tolerance and β-Cell Function After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Surgery
Morten Hindsø, Nora Hedbäck, Maria S. Svane, Andreas Møller, Christoffer Martinussen, Nils B. Jørgensen, Carsten Dirksen, Lærke S. Gasbjerg, Viggo B. Kristiansen, Bolette Hartmann, Mette M. Rosenkilde, Jens J. Holst, Sten Madsbad, and Kirstine N. Bojsen-Møller
April
Inflammatory Cell Infiltration Into Islets Without PD-L1 Expression Is Associated With the Development of Immune Checkpoint Inhibitor–Related Type 1 Diabetes in Genetically Susceptible Patients
Satoshi Kawata, Junji Kozawa, Sho Yoneda, Yukari Fujita, Risa Kashiwagi-Takayama, Takekazu Kimura, Yoshiya Hosokawa, Megu Y. Baden, Sae Uno, Rikako Uenaka, Kazuyuki Namai, Yoko Koh, Yoshito Tomimaru, Haruhiko Hirata, Motohide Uemura, Satoshi Nojima, Eiichi Morii, Hidetoshi Eguchi, Akihisa Imagawa, and Iichiro Shimomura
May
Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy
Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, and Kyriaki Thermos
June
Liver-Secreted Hexosaminidase A Regulates Insulin-Like Growth Factor Signaling and Glucose Transport in Skeletal Muscle
Magdalene K. Montgomery, Jacqueline Bayliss, Shuai Nie, William de Nardo, Stacey N. Keenan, Marziyeh Anari, Amanuiel Z. Taddese, Nicholas A. Williamson, Geraldine J. Ooi, Wendy A. Brown, Paul R. Burton, Paul Gregorevic, Craig A. Goodman, Kevin I. Watt, and Matthew J. Watt
July
Hematopoietic NLRP3 and AIM2 Inflammasomes Promote Diabetes-Accelerated Atherosclerosis, but Increased Necrosis Is Independent of Pyroptosis
Cheng-Chieh Hsu, Trevor P. Fidler, Jenny E. Kanter, Vishal Kothari, Farah Kramer, Jingjing Tang, Alan R. Tall, and Karin E. Bornfeldt
August
GDF15 Mediates the Effect of Skeletal Muscle Contraction on Glucose-Stimulated Insulin Secretion
Hui Zhang, Anny Mulya, Stephan Nieuwoudt, Bolormaa Vandanmagsar, Ruth McDowell, Elizabeth C. Heintz, Elizabeth R.M. Zunica, J. Jason Collier, Nadejda Bozadjieva-Kramer, Randy J. Seeley, Christopher L. Axelrod, and John P. Kirwan
September
Identification of Hypothalamic Glucoregulatory Neurons That Sense and Respond to Changes in Glycemia
Jennifer D. Deem, David Tingley, Anne-Mette Bjerregaard, Anna Secher, Owen Chan, Chukwuemeka Uzo, Nicole E. Richardson, Elizabeth Giering, Tammy Doan, Bao A. Phan, Brandon Wu, Jarrad M. Scarlett, Gregory J. Morton, and Michael W. Schwartz
October
Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic α-Cells
Sarah L. Armour, Alexander Frueh, Margarita V. Chibalina, Haiqiang Dou, Lidia Argemi-Muntadas, Alexander Hamilton, Georgios Katzilieris-Petras, Peter Carmeliet, Benjamin Davies, Thomas Moritz, Lena Eliasson, Patrik Rorsman, and Jakob G. Knudsen
November
Establishment of Pancreatic β-Cell–Specific Gene Knockout System Based on CRISPR/Cas9 Technology With AAV8-Mediated gRNA Delivery
Kyosei Ueki, Yuya Nishida, Shuhei Aoyama, Hirotsugu Uzawa, Akiko Kanai, Minami Ito, Koki Ikeda, Hitoshi Iida, Takeshi Miyatsuka, and Hirotaka Watada
December
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation
Cynthia T. Luk, Carmen K. Chan, Felix Chiu, Sally Yu Shi, Paraish S. Misra, Yu Zhe Li, Evan Pollock-Tahiri, Stephanie A. Schroer, Harsh R. Desai, Tharini Sivasubramaniyam, Erica P. Cai, Mansa Krishnamurthy, Daniel J. Han, Apu Chowdhury, Rukhsana Aslam, Darren A. Yuen, Anne Hakem, Razqallah Hakem, and Minna Woo
