Background: Few studies have reported glycemic control in the hospital and post-discharge period in older adults using CGM. Thus, we combined data from 2 RCTs using CGM in 141 insulin-treated participants in the hospital and after discharge. We compared CGM glycemic metrics in 33 participants ≥65 years (mean 70±4) to 108 adults <65 years (mean 52±9 years) with CGM data during hospitalization and for 10 days after discharge.
Results: Participants had similar BMI and total insulin use during hospitalization. Older adults had lower admission HbA1c and blood glucose (BG) compared to younger adults. When assessing CGM glycemic metrics, older adults spent a greater percentage of time in range (TIR, 70-180 mg/dL) during hospitalization (p=0.009) and post-discharge (p=0.02) compared to participants <65. Comparing CGM versus POCT in older adults, CGM exhibited higher detection of hypoglycemic events (<70 and <54 mg/dl, p <0.0001). In addition, older adults had lower glycemic variability (GV) during admission, but similar GV during the post-discharge period.
Conclusion: Compared to younger adults, older adults have better glucose control during hospitalization and post-discharge periods. CGM usage was associated with higher detection of hypoglycemia during hospitalization and post-discharge when compared to POCT in older adults which might improve diabetes care in this population.
T. Idrees: None. S. Kantipudi: None. Z. Zabala: None. B. Moazzami: None. M.A. Urrutia: None. S. Zhou: None. P. Vellanki: Consultant; Eli Lilly and Company. L. Peng: None. G. Umpierrez: Research Support; Abbott, Bayer Inc., Dexcom, Inc., AstraZeneca. Advisory Panel; Dexcom, Inc.
