Introduction & Objective: Obesity, a disease increasing cardiometabolic risks and mortality, often accompanies protein-calorie malnutrition (PCM). PCM has been associated with delayed recovery from diseases. This study explores clinical outcomes in obese patients without DM co-diagnosed with PCM. Conducted as an observational study, it utilized data from the National Inpatient Sample from 2017 to 2020 focusing on obese adults over 18 years, with a BMI >30 kg/m^2, and PCM diagnosis, excluding those under 18 or with DM. Multivariable logistic and Poisson regression analyses determined the clinical outcomes, considering a p-value <0.05 significant. Among 11,979,333 obese adults without DM, 1.5% had PCM who were predominantly white males. The study compared PCM and non-PCM groups, revealing higher rates in % in the PCM group for conditions like anemia (26.8 vs 13.4), dyslipidemia (33 vs 31.6) pulm HTN (7 vs 4), HF (26.6 vs 16), Afib (22.8 vs 13.7), PVD (3.7 vs 2.1), ACS (5.4 vs 4.3), COPD (21.4 vs 14.6), CKD (21.9 vs 11), PE (7.8 vs 5) and incidence alcohol use (8.4 vs 4.5). The former group also had worse primary and secondary outcomes as detailed in Table 1. The findings underscore the importance of obesity management in such populations for better clinical outcomes and prognosis.
S. Kishore: None. L. Khokhlov: None. G.E. Ajenaghughrure: None. F.R. Mateo: None. G. Kishore: None. T. Ikpeze: None. P. Rajbhandari: None. S. Rai: None. A. Mishra: None.
