Women with pGDM are at high risk for T2D. Yet, engagement of this population in lifestyle change programs (LCPs) is low. We evaluated the effect of a tailored diabetes prevention approach on engagement and health outcomes.
This unrandomized cohort study engaged women with pGDM in an informed decision-making process to discuss T2D risk, explore preferences for a LCP, and select a LCP aligned with priorities. Seven evidence-based LCPs with a variety of delivery modes, duration, time of day, and childcare availability were offered free of charge. The primary outcome was LCP engagement. Secondary outcomes were psychosocial questionnaires and clinical measures at baseline, 6 months, and 12 months. Paired t-tests compared changes over time.
We consented 116 women (34.9 ± 5.7 y). Ninety-six participants were included in data analysis after exclusions due to pregnancy (n=9) and BMI <25 (n=11). Engagement was 78 percent at 6 months and 71 percent at 12 months. Psychosocial and clinical measures were stable at all time points.
A tailored diabetes prevention strategy is feasible and acceptable in women with pGDM, even during the COVID-19 pandemic and shutdown, which impacted the outcomes. LCPs that meet the unique priorities of women with pGDM are needed to optimize engagement and outcomes.
J.M. Pike: None. K. Haberlin-Pittz: None. L.A. Machuca: None. B.M. McKinney: None. L. Yazel: None. A. Kotarski: None. T.S. Hannon: Advisory Panel; Eli Lilly and Company.
Funding was provided by the Indiana University Grand Challenge Precision Health Initiative grant
