731-P: Retrospective Observational Study on the Impact of Digital Therapy on Glycemic Control in Indian Type 2 Diabetes Patients

Introduction: Amidst increasing Type 2 Diabetes in India, novel diabetes management methods are essential. This study evaluates the real-world effects of a digital therapeutic on glycemic control in Indian T2DM patients, reflecting the potential of technology-based interventions.

Methods: A retrospective observational study involved 250 Indian T2DM patients using a digital therapeutic for at least six months. The platform provided personalized dietary, exercise guidance, medication reminders, and educational content. Primary outcomes measured were changes in Hemoglobin A1c (HbA1c) levels from baseline to six months. Secondary outcomes included fasting blood glucose changes and patient adherence. Data were analyzed using paired t-tests and regression models to adjust for confounders.

Results: After six months of using the digital therapeutic, patients showed a significant reduction in HbA1c levels (mean decrease of 0.9%, p<0.001). Fasting blood glucose also significantly decreased (average reduction of 20 mg/dL, p<0.01). High adherence to the application was associated with greater improvements in glycemic control. Subgroup analyses indicated more pronounced benefits in patients with higher baseline HbA1c levels.

Conclusion: The digital therapeutic significantly improved glycemic control in Indian T2DM patients, especially those with initially poor control. This indicates digital interventions as effective supplements to conventional diabetes management in India. More extensive, long-term studies are needed to validate these findings and explore lasting effects.