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Perspectives in Diabetes

Attenuated Fibrinolysis and Accelerated Atherogenesis in Type II Diabetic Patients

David J Schneider; Thomas K Nordt; Burton E Sobel

Abstract

View articletitled, Attenuated Fibrinolysis and Accelerated Atherogenesis in Type II Diabetic Patients

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Topics: atherogenesis , attenuation , fibrinolysis , insulin , plasminogen activator inhibitor 1

Diabetes January 1993, Vol.42, 1-7. doi:https://doi.org/10.2337/diab.42.1.1

Editorials

Vascular Thrombosis in Type II Diabetes Mellitus

John A Colwell

View articletitled, Vascular Thrombosis in Type II Diabetes Mellitus

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Topics: diabetes mellitus, type 2 , thrombosis

Diabetes January 1993, Vol.42, 8-11. doi:https://doi.org/10.2337/diab.42.1.8

Original Articles

Effect of Hypoxia on Insulin Secretion by Isolated Rat and Canine Islets of Langerhans

Keith E Dionne; Clark K Colton; Martin Lyarmush

Abstract

View articletitled, Effect of Hypoxia on Insulin Secretion by Isolated Rat and Canine Islets of Langerhans

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Topics: endocrine pancreas , hypoxia , insulin secretion

Diabetes January 1993, Vol.42, 12-21. doi:https://doi.org/10.2337/diab.42.1.12

Increased Proinsulin/Insulin Ratio in Pancreas Extracts of Hyperglycemic Rats

Jack L Leahy

Abstract

View articletitled, Increased Proinsulin/Insulin Ratio in Pancreas Extracts of Hyperglycemic Rats

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Topics: hyperglycemic agents , insulin , pancreatic extracts , proinsulin , rats

Diabetes January 1993, Vol.42, 22-27. doi:https://doi.org/10.2337/diab.42.1.22

Effects of Ethanol on Carbohydrate Metabolism in the Elderly

Guenther Boden; Xinhua Chen; Richard Desantis; John White; Maria Mozzoli

Abstract

View articletitled, Effects of Ethanol on Carbohydrate Metabolism in the Elderly

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Topics: carbohydrate metabolism , ethanol , older adult

Diabetes January 1993, Vol.42, 28-34. doi:https://doi.org/10.2337/diab.42.1.28

Calcium Is Essential in Normalizing Intolerance to Glucose That Accompanies Vitamin D Depletion In Vivo

Christine Beaulieu; Rena Kestekian; Jana Havrankova; Marielle Gascon-Barré

Abstract

View articletitled, Calcium Is Essential in Normalizing Intolerance to Glucose That Accompanies Vitamin D Depletion In Vivo

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Topics: calcium , glucose , vitamin d

Diabetes January 1993, Vol.42, 35-43. doi:https://doi.org/10.2337/diab.42.1.35

Adoptive Transfer of Diabetes Into Immunodeficient NOD-scid/scid Mice: Relative Contributions of CD4⁺ and CD8⁺ T-Cells From Diabetic Versus Prediabetic NOD.NON-Thy-1^a Donors

Sherri W Christianson; Leonard D Shultz; Edward H Leiter

Abstract

View articletitled, Adoptive Transfer of Diabetes Into Immunodeficient NOD-scid/scid Mice: Relative Contributions of CD4+ and CD8+ T-Cells From Diabetic Versus Prediabetic NOD.NON-Thy-1a Donors

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Topics: adoptive transfer , donors , immunologic deficiency syndromes , prediabetes , scid mice

Diabetes January 1993, Vol.42, 44-55. doi:https://doi.org/10.2337/diab.42.1.44

Interaction of lnterleukin-1 With Islet β-Cells: Distinction Between Indirect, Aspecific Cytotoxicity and Direct, Specific Functional Suppression

Zhidong Ling; Peter A In'T Veld; Daniel G Pipeleers

Abstract

View articletitled, Interaction of lnterleukin-1 With Islet β-Cells: Distinction Between Indirect, Aspecific Cytotoxicity and Direct, Specific Functional Suppression

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Topics: cytotoxicity , psychological suppression , interleukin-1 , cytokine , hormones

Diabetes January 1993, Vol.42, 56-65. doi:https://doi.org/10.2337/diab.42.1.56

Nuclear Protein—Binding Analysis of a GC-Rich Insulin-Receptor Promoter Regulatory Region

James R Levy; Victoria Hug

Abstract

View articletitled, Nuclear Protein—Binding Analysis of a GC-Rich Insulin-Receptor Promoter Regulatory Region

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Topics: insulin receptor , nuclear proteins , regulatory sequences, nucleic acid

Diabetes January 1993, Vol.42, 66-73. doi:https://doi.org/10.2337/diab.42.1.66

Galanin-Stimulated High-Affinity GTPase Activity in Plasma Membranes From RINm5F Cells

G Skoglund; C R Bliss; G W G Sharp

Abstract

View articletitled, Galanin-Stimulated High-Affinity GTPase Activity in Plasma Membranes From RINm5F Cells

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Topics: affinity , cell membrane , galanin , guanosine triphosphate phosphohydrolases

Diabetes January 1993, Vol.42, 74-79. doi:https://doi.org/10.2337/diab.42.1.74

Differential Regulation of Glucose Transport and Transporters by Glucose in Vascular Endothelial and Smooth Muscle Cells

Nurit Kaiser; Shlomo Sasson; Edward P Feener; Nizza Boukobza-Vardi; Shinya Higashi; David E Moller; Sandra Davidheiser; Ronald J Przybylski; George L King

Abstract

View articletitled, Differential Regulation of Glucose Transport and Transporters by Glucose in Vascular Endothelial and Smooth Muscle Cells

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Topics: endothelium , glucose , glucose transport , membrane transport proteins , myocytes, smooth muscle

Diabetes January 1993, Vol.42, 80-89. doi:https://doi.org/10.2337/diab.42.1.80

The Role of Histocompatibility Antigens in Transplantation of Isolated Islets of Langerhans in the Rat

Wolfgang F A Hiller; Birte Steiniger; Jürgen Klempnauer

Abstract

View articletitled, The Role of Histocompatibility Antigens in Transplantation of Isolated Islets of Langerhans in the Rat

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Topics: endocrine pancreas , histocompatibility antigens , transplantation

Diabetes January 1993, Vol.42, 90-97. doi:https://doi.org/10.2337/diab.42.1.90

Insulin Secretory Function in Relation to Transplanted Islet Mass in STZ-Induced Diabetic Rats

Brian W Tobin; Jamie T Lewis; Dawn Z X Chen; Diane T Finegood

Abstract

View articletitled, Insulin Secretory Function in Relation to Transplanted Islet Mass in STZ-Induced Diabetic Rats

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Topics: insulin , rats , streptozocin

Diabetes January 1993, Vol.42, 98-105. doi:https://doi.org/10.2337/diab.42.1.98

Distribution of Type II Diabetes in Nuclear Families

Joanne T E Cook; Andrew T Hattersley; Jonathan C Levy; Pushpa Patel; James S Wainscoat; T Derek; R Hockaday; Robert C Turner

Abstract

View articletitled, Distribution of Type II Diabetes in Nuclear Families

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Topics: diabetes mellitus, type 2

Diabetes January 1993, Vol.42, 106-112. doi:https://doi.org/10.2337/diab.42.1.106

Tissue Kallikrein and Tonin Levels in Submandibular Glands of STZ-Induced Diabetic Rats and the Effects of Insulin

Ka-Ming Chan; Julie Chao; Gordon B Proctor; John R Garrett; Deepak K Shori; Leigh C Anderson

Abstract

View articletitled, Tissue Kallikrein and Tonin Levels in Submandibular Glands of STZ-Induced Diabetic Rats and the Effects of Insulin

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Topics: insulin , rats , streptozocin , submandibular gland , tissue kallikrein

Diabetes January 1993, Vol.42, 113-117. doi:https://doi.org/10.2337/diab.42.1.113

Role for Protein Kinase C in the Mediation of Increased Fibronectin Accumulation by Mesangial Cells Grown in High-Glucose Medium

Rebecca K Studer; Patricia A Craven; Frederick R DeRubertis

Abstract

View articletitled, Role for Protein Kinase C in the Mediation of Increased Fibronectin Accumulation by Mesangial Cells Grown in High-Glucose Medium

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Topics: fibronectins , glucose , mesangial cells , protein kinase c

Diabetes January 1993, Vol.42, 118-126. doi:https://doi.org/10.2337/diab.42.1.118

Increase in Simultaneous Coexpression of Naive and Memory Lymphocyte Markers at Diagnosis of IDDM

Rebecca A Smerdon; Mark Peakman; Munther J Hussain; Lorenzo Alviggi; Peter J Watkins; R David G Leslie; Diego Vergani

Abstract

View articletitled, Increase in Simultaneous Coexpression of Naive and Memory Lymphocyte Markers at Diagnosis of IDDM

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Topics: diabetes mellitus, type 1 , lymphocytes , memory

Diabetes January 1993, Vol.42, 127-133. doi:https://doi.org/10.2337/diab.42.1.127

Characterization of the Extracellular Matrix—Containing Giant Perivascular Spaces in the NOD Mouse Thymus

Wilson Savino; Claude Carnaud; Jian-Jian Luan; Jean-François Bach; Mireille Dardenne

Abstract

View articletitled, Characterization of the Extracellular Matrix—Containing Giant Perivascular Spaces in the NOD Mouse Thymus

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Topics: extracellular matrix , mice, inbred nod , thymus gland

Diabetes January 1993, Vol.42, 134-140. doi:https://doi.org/10.2337/diab.42.1.134

Abnormal Agonist-Stimulated Cardiac Parasympathetic Acetylcholine Release in Streptozocin-Induced Diabetes

Luigi Uccioli; Paolo Magnani; Pietro Tilli; Patrizia Cotroneo; Andrea Manto; Aldo Virgilio Greco; Anders A F Sima; Douglas A Greene; Guido Menzinger; Giovanni Ghirlanda

Abstract

View articletitled, Abnormal Agonist-Stimulated Cardiac Parasympathetic Acetylcholine Release in Streptozocin-Induced Diabetes

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Topics: acetylcholine , agonists , streptozocin

Diabetes January 1993, Vol.42, 141-147. doi:https://doi.org/10.2337/diab.42.1.141

Endothelium-Dependent Vascular Relaxation in Patients With Type I Diabetes

Paul Smits; Jan-Auke Kapma; Marie-Cécile Jacobs; Jos Lutterman; Theo Then

Abstract

View articletitled, Endothelium-Dependent Vascular Relaxation in Patients With Type I Diabetes

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Topics: diabetes mellitus, type 1 , endothelium , mean cell hemoglobin measurement , vasodilators

Diabetes January 1993, Vol.42, 148-153. doi:https://doi.org/10.2337/diab.42.1.148

Incidence of NIDDM and Impaired Glucose Tolerance in Hypertensive Subjects: The San Antonio Heart Study

Philip A Morales; Braxton D Mitchell; Rodolfo A Valdez; Helen P Hazuda; Michael P Stern; Steven M Haffner

Abstract

View articletitled, Incidence of NIDDM and Impaired Glucose Tolerance in Hypertensive Subjects: The San Antonio Heart Study

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Topics: diabetes mellitus, type 2 , glucose intolerance , heart , hypertension

Diabetes January 1993, Vol.42, 154-161. doi:https://doi.org/10.2337/diab.42.1.154

Normal Proinsulin Responses to Glucose in Mild Type II Subjects With Subnormal Insulin Response

Jonathan C Levy; Penelope M Clark; C Nicholas Hales; Robert C Turner

Abstract

View articletitled, Normal Proinsulin Responses to Glucose in Mild Type II Subjects With Subnormal Insulin Response

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Topics: glucose , insulin , proinsulin

Diabetes January 1993, Vol.42, 162-169. doi:https://doi.org/10.2337/diab.42.1.162

Effect of High Glucose on Type IV Collagen Production by Cultured Glomerular Epithelial, Endothelial, and Mesangial Cells

Thomas Danne; Mary Jane Spiro; Robert G Spiro

Abstract

View articletitled, Effect of High Glucose on Type IV Collagen Production by Cultured Glomerular Epithelial, Endothelial, and Mesangial Cells

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Topics: collagen type iv , endothelium , epithelium , glucose , kidney glomerulus

Diabetes January 1993, Vol.42, 170-177. doi:https://doi.org/10.2337/diab.42.1.170

Picotamide, a Dual TXB Synthetase Inhibitor and TXB Receptor Antagonist, Reduces Exercise-Induced Albuminuria in Microalbuminuric Patients With NIDDM

Andrea Giustina; Simonetta Bossoni; Antonino Cimino; M Teresa Comini; Nadia Gazzoli; G Battista Leproux; William B Wehrenberg; Giuseppe Romanelli; Gianni Giustina

Abstract

View articletitled, Picotamide, a Dual TXB Synthetase Inhibitor and TXB Receptor Antagonist, Reduces Exercise-Induced Albuminuria in Microalbuminuric Patients With NIDDM

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Topics: albuminuria , antagonists , diabetes mellitus, type 2 , ligase

Diabetes January 1993, Vol.42, 178-182. doi:https://doi.org/10.2337/diab.42.1.178

Fibronectin-Induced Increase in Mesangial Cell Prostaglandin Release: Effect of Hyperglycemia and PKC Inhibition

Marjorie Dunlop; Rosemary Keogh; Richard G Larkins

Abstract

View articletitled, Fibronectin-Induced Increase in Mesangial Cell Prostaglandin Release: Effect of Hyperglycemia and PKC Inhibition

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Topics: fibronectins , hyperglycemia , mesangial cells , prostaglandins , glucose

Diabetes January 1993, Vol.42, 183-190. doi:https://doi.org/10.2337/diab.42.1.183

Glucose Transport in Human Skeletal Muscle: The In Vivo Response to Insulin

Riccardo C Bonadonna; Maria Pia Saccomani; Lynn Seely; Kathleen Starick Zych; Eleuterio Ferrannini; Claudio Cobelli; Ralph A DeFronzo

Abstract

View articletitled, Glucose Transport in Human Skeletal Muscle: The In Vivo Response to Insulin

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Topics: glucose transport , insulin , skeletal muscles

Diabetes January 1993, Vol.42, 191-198. doi:https://doi.org/10.2337/diab.42.1.191

Glucose Modulates Glucose Transporter Affinity, Glucokinase Activity, and Secretory Response in Rat Pancreatic β-Cells

Francesco Purrello; Massimo Buscema; Agata M Rabuazzo; Venera Caltabiano; Fiorella Forte; Carmela Vinci; Mario Vetri; Riccardo Vigneri

Abstract

View articletitled, Glucose Modulates Glucose Transporter Affinity, Glucokinase Activity, and Secretory Response in Rat Pancreatic β-Cells

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Topics: affinity , glucokinase , glucose , glucose transporter , pancreas

Diabetes January 1993, Vol.42, 199-205. doi:https://doi.org/10.2337/diab.42.1.199

Rapid Publication

Muscle-Specific Expression of Human Insulin Receptor in Transgenic Mice

Heike Benecke; Jeffrey S Flier; Nadia Rosenthal; Kenneth Siddle; Harald H Klein; David E Moller

Abstract

View articletitled, Muscle-Specific Expression of Human Insulin Receptor in Transgenic Mice

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Topics: insulin receptor , mice, transgenic

Diabetes January 1993, Vol.42, 206-212. doi:https://doi.org/10.2337/diab.42.1.206

Organization Section

View articletitled, Organization Section

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Diabetes January 1993, Vol.42, 213-214. doi:https://doi.org/10.2337/diab.42.1.213

Instructions for Authors

View articletitled, Instructions for Authors

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Diabetes January 1993, Vol.42, 215-218. doi:https://doi.org/10.2337/diab.42.1.215

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