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Volume 44, Issue 8
1 August 1995
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ISSN 0012-1797
EISSN 1939-327X
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Perspectives in Diabetes

Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications
Roger H Unger
View articletitled, Lipotoxicity in the Pathogenesis of Obesity-Dependent NIDDM: Genetic and Clinical Implications
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Topics: diabetes mellitus, type 2 , genetics , obesity
Diabetes August 1995, Vol.44, 863-870. doi:https://doi.org/10.2337/diab.44.8.863

Original Articles

Intrathymic Transplantation of Islet Antigen Affects CD8+ Diabetogenic T-Cells Resulting in Tolerance to Autoimmune IDDM
Elizabeth E Baumann; Frank Buckingham; Kevan C Herold
View articletitled, Intrathymic Transplantation of Islet Antigen Affects CD8<sup>+</sup> Diabetogenic T-Cells Resulting in Tolerance to Autoimmune IDDM
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Topics: antigens , autoimmunity , diabetes mellitus, type 1 , t-lymphocytes , transplantation
Diabetes August 1995, Vol.44, 871-877. doi:https://doi.org/10.2337/diab.44.8.871
Involvement of ATP-Sensitive K+ Channels in Free Radical–Mediated Inhibition of Insulin Secretion in Rat Pancreatic β-Cells
Mitsuhiro Nakazaki; Masafumi Kakei; Nobuyuki Koriyama; Hiromitsu Tanaka
View articletitled, Involvement of ATP-Sensitive K<sup>+</sup> Channels in Free Radical–Mediated Inhibition of Insulin Secretion in Rat Pancreatic β-Cells
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Topics: free radicals , insulin secretion , pancreas
Diabetes August 1995, Vol.44, 878-883. doi:https://doi.org/10.2337/diab.44.8.878
Peroxidative Stress in Diabetic Blood Vessels: Reversal by Pancreatic Islet Transplantation
Galen M Pieper; Milan Jordan; Lynn A Dondlinger; Mark B Adams; Allan M Roza
View articletitled, Peroxidative Stress in Diabetic Blood Vessels: Reversal by Pancreatic Islet Transplantation
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Topics: islets of langerhans transplantation , stress
Diabetes August 1995, Vol.44, 884-889. doi:https://doi.org/10.2337/diab.44.8.884
Exposure of Adhesion Molecules on Activated Platelets in Patients with Newly Diagnosed IDDM Is Not Normalized by Near-Normoglycemia
Diethelm Tschoepe; Elke Driesch; Barbara Schwippert; H-Karel Nieuwenhuis; Friedrich Arnold Gries
View articletitled, Exposure of Adhesion Molecules on Activated Platelets in Patients with Newly Diagnosed IDDM Is Not Normalized by Near-Normoglycemia
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Topics: blood platelets , cell adhesion molecules , diabetes mellitus, type 1
Diabetes August 1995, Vol.44, 890-894. doi:https://doi.org/10.2337/diab.44.8.890
Effect of a Specific Endothelin Receptor A Antagonist on mRNA Levels for Extracellular Matrix Components and Growth Factors in Diabetic Glomeruli
Tsukasa Nakamura; Isao Ebihara; Mitsumine Fukui; Yasuhiko Tomino; Hikaru Koide
View articletitled, Effect of a Specific Endothelin Receptor A Antagonist on mRNA Levels for Extracellular Matrix Components and Growth Factors in Diabetic Glomeruli
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Topics: antagonists , endothelin receptors , extracellular matrix , growth factor , kidney glomerulus
Diabetes August 1995, Vol.44, 895-899. doi:https://doi.org/10.2337/diab.44.8.895
Brainstem Dysfunction Is Provoked by a Less Pronounced Hypoglycemic Stimulus in Diabetic BB Rats
Ralph J Jacob; Andrew B Weber; James Dziura; Jennifer Morgen; Robert S Sherwin
View articletitled, Brainstem Dysfunction Is Provoked by a Less Pronounced Hypoglycemic Stimulus in Diabetic BB Rats
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Topics: brain stem , hypoglycemic agents , rats, inbred bb
Diabetes August 1995, Vol.44, 900-905. doi:https://doi.org/10.2337/diab.44.8.900
Comparative Study of the Protective Effect Afforded by Intravenous Administration of Bovine or Ovine Insulin to Young NOD Mice
Patricia R Hutchings; Anne Cooke
View articletitled, Comparative Study of the Protective Effect Afforded by Intravenous Administration of Bovine or Ovine Insulin to Young NOD Mice
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Topics: cattle , insulin , intravenous infusion procedures , intravenous route of drug administration , mice, inbred nod
Diabetes August 1995, Vol.44, 906-910. doi:https://doi.org/10.2337/diab.44.8.906
Excessive Secretion of Insulin Precursors Characterizes and Predicts Gestational Diabetes
Robert A Swinn; Nicholas J Wareham; Robert Gregory; Victoria Curling; Penelope M Clark; Kevin J Dalton; Owen M Edwards; Stephen O'Rahilly
View articletitled, Excessive Secretion of Insulin Precursors Characterizes and Predicts Gestational Diabetes
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Topics: gestational diabetes , insulin secretion
Diabetes August 1995, Vol.44, 911-915. doi:https://doi.org/10.2337/diab.44.8.911
Ten-Year Incidence of Gross Proteinuria in People With Diabetes
Ronald Klein; Barbara E K Klein; Scot E Moss; Karen J Cruickshanks
View articletitled, Ten-Year Incidence of Gross Proteinuria in People With Diabetes
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Topics: proteinuria
Diabetes August 1995, Vol.44, 916-923. doi:https://doi.org/10.2337/diab.44.8.916
Hyperglycemia-Induced Thrombin Formation in Diabetes: The Possible Role of Oxidative Stress
Antonio Ceriello; Roberta Giacomello; Giuliana Stel; Enrico Motz; Claudio Taboga; Laura Tonutti; Mario Pirisi; Edmondo Falleti; Ettore Bartoli
View articletitled, Hyperglycemia-Induced Thrombin Formation in Diabetes: The Possible Role of Oxidative Stress
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Topics: hyperglycemia , oxidative stress , thrombin
Diabetes August 1995, Vol.44, 924-928. doi:https://doi.org/10.2337/diab.44.8.924
Decreased Degradative Enzymes in Mesangial Cells Cultured in High Glucose Media
David J Leehey; Ruo Hua Song; Nahid Alavi; Ashok K Singh
View articletitled, Decreased Degradative Enzymes in Mesangial Cells Cultured in High Glucose Media
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Topics: enzymes , glucose , mesangial cells
Diabetes August 1995, Vol.44, 929-935. doi:https://doi.org/10.2337/diab.44.8.929
Insulin Action and Glucose Metabolism in Nondiabetic Control and NIDDM Subjects: Comparison Using Human Skeletal Muscle Cell Cultures
Robert R Henry; Leslie Abrams; Svetlana Nikoulina; Theodore P Ciaraldi
View articletitled, Insulin Action and Glucose Metabolism in Nondiabetic Control and NIDDM Subjects: Comparison Using Human Skeletal Muscle Cell Cultures
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Topics: diabetes mellitus, type 2 , glucose metabolism , insulin , skeletal myocytes
Diabetes August 1995, Vol.44, 936-946. doi:https://doi.org/10.2337/diab.44.8.936
Kinetics of Insulin Action In Vivo: Identification of Rate-Limiting Steps
Philip D G Miles; Matteo Levisetti; Donna Reichart; Mousa Khoursheed; A R Moossa; Jerrold M Olefsky
View articletitled, Kinetics of Insulin Action In Vivo: Identification of Rate-Limiting Steps
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Topics: insulin , kinetics
Diabetes August 1995, Vol.44, 947-953. doi:https://doi.org/10.2337/diab.44.8.947
Insulin Sensitivity Accounts for Glucose and Lactate Kinetics After Intravenous Glucose Injection
Richard M Watanabe; Jennifer Lovejoy; Garry M Steil; Mario DiGirolamo; Richard N Bergman
View articletitled, Insulin Sensitivity Accounts for Glucose and Lactate Kinetics After Intravenous Glucose Injection
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Topics: glucose , glucose, parenteral form , insulin sensitivity , kinetics , lactates
Diabetes August 1995, Vol.44, 954-962. doi:https://doi.org/10.2337/diab.44.8.954
DR-BB Rat Thymus Contains Thymocyte Populations Predisposed to Autoreactivity
Barbara J Whalen; Aldo A Rossini; John P Mordes; Dale L Greiner
View articletitled, DR-BB Rat Thymus Contains Thymocyte Populations Predisposed to Autoreactivity
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Topics: thymocytes , thymus gland , diabetes mellitus, type 1
Diabetes August 1995, Vol.44, 963-967. doi:https://doi.org/10.2337/diab.44.8.963
The Relationship of Glycemic Exposure (HbA1c) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial
The Diabetes Control and Complications Trial Research Group
View articletitled, The Relationship of Glycemic Exposure (HbA<sub>1c</sub>) to the Risk of Development and Progression of Retinopathy in the Diabetes Control and Complications Trial
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Topics: dcct trial , hemoglobin a, glycosylated , retinal diseases
Diabetes August 1995, Vol.44, 968-983. doi:https://doi.org/10.2337/diab.44.8.968
Insulin Secretory Defect in Zucker fa/fa Rats Is Improved by Ameliorating Insulin Resistance
Christopher J de Souza; Jen H Yu; Deborah D Robinson; Roger G Ulrich; Martin D Meglasson
View articletitled, Insulin Secretory Defect in Zucker <em>fa/fa</em> Rats Is Improved by Ameliorating Insulin Resistance
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Topics: insulin , insulin resistance , rats
Diabetes August 1995, Vol.44, 984-991. doi:https://doi.org/10.2337/diab.44.8.984
Significance of Glutathione Depletion and Oxidative Stress in Early Embryogenesis in Glucose-Induced Rat Embryo Culture
Romulo A Trocino; Shoichi Akazawa; Miwa Ishibashi; Kazunari Matsumoto; Hiroshi Matsuo; Hidefumi Yamamoto; Shinji Goto; Yoshishige Urata; Takahito Kondo; Shigenobu Nagataki
View articletitled, Significance of Glutathione Depletion and Oxidative Stress in Early Embryogenesis in Glucose-Induced Rat Embryo Culture
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Topics: embryo , embryologic development , glucose , glutathione , oxidative stress
Diabetes August 1995, Vol.44, 992-998. doi:https://doi.org/10.2337/diab.44.8.992

Rapid Publication

Identification of Microsatellite Markers Near the Human ob Gene and Linkage Studies in NIDDM-Affected Sib Pairs
Brigid Stirling; Nancy J Cox; Graeme I Bell; Craig L Hanis; Richard S Spielman; Patrick Concannon
View articletitled, Identification of Microsatellite Markers Near the Human <em>ob</em> Gene and Linkage Studies in NIDDM-Affected Sib Pairs
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Topics: diabetes mellitus, type 2 , genes , microsatellite repeats
Diabetes August 1995, Vol.44, 999-1001. doi:https://doi.org/10.2337/diab.44.8.999

Letter to the Editor

The Insulin Gene Promoter: A Simplified Nomenclature
Michael German; Stephen Ashcroft; Kevin Docherty; Helena Edlund; Thomas Edlund; Steven Goodison; Hiroo Imura; Giulia Kennedy; Ole Madsen; Danielle Melloul; Larry Moss; Karl Olson; M Alan Permutt; Jacques Philippe; R Paul Robertson; William J Rutter; Palle Serup; Roland Stein; Donald Steiner; Ming-Jer Tsai; Michael D Walker
View articletitled, The Insulin Gene Promoter: A Simplified Nomenclature
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Topics: genes , insulin
Diabetes August 1995, Vol.44, 1002-1004. doi:https://doi.org/10.2337/diab.44.8.1002

Organization Section

Organization Section
View articletitled, Organization Section
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Diabetes August 1995, Vol.44, 1005-1006. doi:https://doi.org/10.2337/diab.44.8.1005

SI Units Table

Système International (SI) Units Table
View articletitled, Système International (SI) Units Table
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Diabetes August 1995, Vol.44, 1007-1008. doi:https://doi.org/10.2337/diab.44.8.1007
MRI Metrics of Cerebral Endothelial Cell–Derived Exosomes for the Treatment of Cognitive Dysfunction Induced in Aging Rats Subjected to Type 2 Diabetes
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis
Elevated First-Trimester Neutrophil Count Is Closely Associated With the Development of Maternal Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes
Increased Risk of Diabetes and Diabetic Ketoacidosis Associated With COVID-19
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