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Volume 45, Issue 10

October 1996

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Front Matter
Back Matter

ISSN 0012-1797

EISSN 1939-327X

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Perspectives in Diabetes
Original Articles
Rapid Publications
SI Units Table
Organization Section

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Perspectives in Diabetes

The Absence of a Glycemic Threshold for the Development of Long-Term Complications: The Perspective of the Diabetes Control and Complications Trial

Diabetes Control and Complications Trial (DCCT) Research Group

Abstracts

View articletitled, The Absence of a Glycemic Threshold for the Development of Long-Term Complications: The Perspective of the Diabetes Control and Complications Trial

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Topics: dcct trial

Diabetes October 1996, Vol.45, 1289-1298. doi:https://doi.org/10.2337/diab.45.10.1289

Diabetogenic T-Cell Clones

Kathryn Haskins; Dale Wegmann

Abstract

View articletitled, Diabetogenic T-Cell Clones

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Topics: clone cells , t-lymphocytes , antigens

Diabetes October 1996, Vol.45, 1299-1305. doi:https://doi.org/10.2337/diab.45.10.1299

Original Articles

Dexamethasone-Induced Neuropeptide Y Expression in Rat Islet Endocrine Cells: Rapid Reversibility and Partial Prevention by Insulin

Ulrika Myrsén; Bo Ahrén; Frank Sundler

Abstract

View articletitled, Dexamethasone-Induced Neuropeptide Y Expression in Rat Islet Endocrine Cells: Rapid Reversibility and Partial Prevention by Insulin

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Topics: dexamethasone , endocrine cells , insulin , neuropeptide y

Diabetes October 1996, Vol.45, 1306-1316. doi:https://doi.org/10.2337/diab.45.10.1306

Effects of Glucose Ingestion Versus Infusion on Pulsatile Insulin Secretion: The Incretin Effect Is Achieved by Amplification of Insulin Secretory Burst Mass

Niels Pørksen; Stephen Munn; Jeffery Steers; Johannes D Veldhuis; Peter C Butler

Abstract

View articletitled, Effects of Glucose Ingestion Versus Infusion on Pulsatile Insulin Secretion: The Incretin Effect Is Achieved by Amplification of Insulin Secretory Burst Mass

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Topics: amplification , glucose , incretin , infusion procedures , ingestion

Diabetes October 1996, Vol.45, 1317-1323. doi:https://doi.org/10.2337/diab.45.10.1317

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

Jack F Youngren; Betty A Maddux; Shlomo Sasson; Paolo Sbraccia; Edward B Tapscott; Melvin S Swanson; G Lynis Dohm; Ira D Goldfine

Abstract

View articletitled, Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

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Topics: glucose transport , membrane glycoproteins , obesity , skeletal muscles

Diabetes October 1996, Vol.45, 1324-1328. doi:https://doi.org/10.2337/diab.45.10.1324

Glucosamine-Induced Inhibition of Liver Glucokinase Impairs the Ability of Hyperglycemia to Suppress Endogenous Glucose Production

Nir Barzilai; Meredith Hawkins; Ivo Angelov; Meizhu Hu; Luciano Rossetti

Abstract

View articletitled, Glucosamine-Induced Inhibition of Liver Glucokinase Impairs the Ability of Hyperglycemia to Suppress Endogenous Glucose Production

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Topics: glucokinase , glucosamine , glucose , hyperglycemia , liver

Diabetes October 1996, Vol.45, 1329-1335. doi:https://doi.org/10.2337/diab.45.10.1329

Control of Islet Intercellular Adhesion Molecule-1 Expression by Interferon-α and Hypoxia

Debasis Chakrabarti; Xiaojian Huang; Joanne Beck; Jill Henrich; Nancy McFarland; Roger F L James; Timothy A Stewart

Abstract

View articletitled, Control of Islet Intercellular Adhesion Molecule-1 Expression by Interferon-α and Hypoxia

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Topics: human leukocyte interferon , hypoxia , intercellular adhesion molecule 1 , interferons

Diabetes October 1996, Vol.45, 1336-1343. doi:https://doi.org/10.2337/diab.45.10.1336

Autoantibodies to Protein Tyrosine Phosphatase-Like Proteins In Type I Diabetes: Overlapping Specificities To Phogrin And ICA512/IA-2

Eiji Kawasaki; George S Eisenbarth; Christina Wasmeier; John C Hutton

Abstract

View articletitled, Autoantibodies to Protein Tyrosine Phosphatase-Like Proteins In Type I Diabetes: Overlapping Specificities To Phogrin And ICA512/IA-2

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Topics: autoantibodies , diabetes mellitus, type 1 , phosphoric monoester hydrolases , tyrosine

Diabetes October 1996, Vol.45, 1344-1349. doi:https://doi.org/10.2337/diab.45.10.1344

Both CD4⁺ and CD8⁺ T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction

Wilma Suarez-Pinzon; Ray V Rajotte; Tim R Mosmann; Alex Rabinovitch

Abstract

View articletitled, Both CD4+ and CD8+ T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction

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Topics: human leukocyte interferon , interferons , mice, inbred nod , tissue transplants , t-lymphocytes

Diabetes October 1996, Vol.45, 1350-1357. doi:https://doi.org/10.2337/diab.45.10.1350

The β3-Adrenergic Receptor Gene Trp64Arg Mutation is Overrepresented in Obese Women: Effects on Weight, BMI, Abdominal Fat, Blood Pressure, and Reproductive History in an Elderly Australian Population

Takumi Kurabayashi; David G P Carey; Nigel A Morrison

Abstract

View articletitled, The β3-Adrenergic Receptor Gene Trp64Arg Mutation is Overrepresented in Obese Women: Effects on Weight, BMI, Abdominal Fat, Blood Pressure, and Reproductive History in an Elderly Australian Population

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Topics: abdomen , blood pressure , body mass index procedure , genes , mutation

Diabetes October 1996, Vol.45, 1358-1363. doi:https://doi.org/10.2337/diab.45.10.1358

Supraphysiological Hyperinsulinemia Increases Plasma Leptin Concentrations After 4 h in Normal Subjects

Tapio Utriainen; Raija Malmström; Sari Mäkimattila; Hannele Yki-Järvinen

Abstract

View articletitled, Supraphysiological Hyperinsulinemia Increases Plasma Leptin Concentrations After 4 h in Normal Subjects

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Topics: hyperinsulinism , leptin , plasma

Diabetes October 1996, Vol.45, 1364-1366. doi:https://doi.org/10.2337/diab.45.10.1364

Insulin Levels and the Natural History of Glucose Intolerance in Nauruans

Gary K Dowse; Paul Z Zimmet; Veronica R Collins

Abstract

View articletitled, Insulin Levels and the Natural History of Glucose Intolerance in Nauruans

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Topics: glucose intolerance , insulin

Diabetes October 1996, Vol.45, 1367-1372. doi:https://doi.org/10.2337/diab.45.10.1367

Epinephrine Exerts Opposite Effects on Peripheral Glucose Disposal and Glucose-Stimulated Insulin Secretion: A Stable Label Intravenous Glucose Tolerance Test Minimal Model Study

Angelo Avogaro; Gianna Toffolo; Anna Valerio; Claudio Cobelli

Abstract

View articletitled, Epinephrine Exerts Opposite Effects on Peripheral Glucose Disposal and Glucose-Stimulated Insulin Secretion: A Stable Label Intravenous Glucose Tolerance Test Minimal Model Study

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Topics: epinephrine , glucose , insulin secretion , intravenous glucose tolerance test

Diabetes October 1996, Vol.45, 1373-1378. doi:https://doi.org/10.2337/diab.45.10.1373

Protein Tyrosine Phosphatase 1B Interacts With the Activated Insulin Receptor

B Lynn Seely; Patricia A Staubs; Donna R Reichart; Paulos Berhanu; Kim L Milarski; Alan R Saltiel; Jyotirmoy Kusari; Jerrold M Olefsky

Abstract

View articletitled, Protein Tyrosine Phosphatase 1B Interacts With the Activated Insulin Receptor

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Topics: insulin receptor , protein tyrosine phosphatase

Diabetes October 1996, Vol.45, 1379-1385. doi:https://doi.org/10.2337/diab.45.10.1379

High D-Glucose–Induced Changes in Endothelial Ca²⁺/EDRF Signaling are Due to Generation of Superoxide Anions

Wolfgang F Graier; Sabine Simecek; Walter R Kukovetz; Gert M Kostner

Abstract

View articletitled, High D-Glucose–Induced Changes in Endothelial Ca2+/EDRF Signaling are Due to Generation of Superoxide Anions

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Topics: anions , endothelium , endothelium-dependent relaxing factors , glucose , nitric oxide

Diabetes October 1996, Vol.45, 1386-1395. doi:https://doi.org/10.2337/diab.45.10.1386

Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

Antoine Avignon; Kouji Yamada; Xiaoping Zhou; Barbara Spencer; Osvaldo Cardona; Shereen Saba-Siddique; Lamar Galloway; Mary L Standaert; Robert V Farese

Abstract

View articletitled, Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

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Topics: glycogen synthesis , insulin , obesity , protein kinase c , rats, zucker

Diabetes October 1996, Vol.45, 1396-1404. doi:https://doi.org/10.2337/diab.45.10.1396

The ApoB-100 Gene EcoRI Polymorphism Influences the Relationship Between Features of the Insulin Resistance Syndrome and the Hyper-ApoB and Dense LDL Phenotype in Men

Marie-Claude Vohl; André Tchernof; France T Dionne; Sital Moorjani; Denis Prud'homme; Claude Bouchard; André Nadeau; Paul J Lupien; Jean-Pierre Després

Abstract

View articletitled, The ApoB-100 Gene EcoRI Polymorphism Influences the Relationship Between Features of the Insulin Resistance Syndrome and the Hyper-ApoB and Dense LDL Phenotype in Men

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Topics: apolipoprotein b-100 , apolipoproteins b , deoxyribonuclease ecori , genes , insulin resistance

Diabetes October 1996, Vol.45, 1405-1411. doi:https://doi.org/10.2337/diab.45.10.1405

cAMP-Dependent Phosphorylation of the Cardiac-Type α1 Subunit of the Voltage-Dependent Ca²⁺ channel in a murine pancreatic β-cell line

Margarita Leiser; Norman Fleischer

Abstract

View articletitled, cAMP-Dependent Phosphorylation of the Cardiac-Type α1 Subunit of the Voltage-Dependent Ca2+ channel in a murine pancreatic β-cell line

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Topics: cyclic amp , mice , pancreas , phosphorylation

Diabetes October 1996, Vol.45, 1412-1418. doi:https://doi.org/10.2337/diab.45.10.1412

The Rat T-Cell Surface Protein RT6 Is Associated With src Family Tyrosine Kinases and Generates an Activation Signal

Mark R Rigby; Rita Bortell; Dale L Greiner; Michael P Czech; Jes K Klarlund; John P Mordes; Aldo A Rossini

Abstract

View articletitled, The Rat T-Cell Surface Protein RT6 Is Associated With src Family Tyrosine Kinases and Generates an Activation Signal

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Topics: membrane proteins , src-family kinases , t-lymphocytes

Diabetes October 1996, Vol.45, 1419-1426. doi:https://doi.org/10.2337/diab.45.10.1419

Rapid Publications

Diazoxide Treatment at Onset Preserves Residual Insulin Secretion in Adults with Autoimmune Diabetes

E Björk; C Berne; O Kämpe; L Wibell; P Oskarsson; F A Karlsson

Abstract

View articletitled, Diazoxide Treatment at Onset Preserves Residual Insulin Secretion in Adults with Autoimmune Diabetes

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Topics: autoimmunity , diazoxide , insulin secretion

Diabetes October 1996, Vol.45, 1427-1430. doi:https://doi.org/10.2337/diab.45.10.1427

Diadenosine Polyphosphates: A Novel Class of Glucose-Induced Intracellular Messengers in the Pancreatic β-Cell

Cristina Ripoll; Franz Martin; Juan Manuel Rovira; Jesús Pintor; María Teresa Miras-Portugal; Bernat Soria

Abstract

View articletitled, Diadenosine Polyphosphates: A Novel Class of Glucose-Induced Intracellular Messengers in the Pancreatic β-Cell

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Topics: glucose , pancreas , polyphosphates

Diabetes October 1996, Vol.45, 1431-1434. doi:https://doi.org/10.2337/diab.45.10.1431

Insulin and Cortisol Promote Leptin Production in Cultured Human Fat Cells

Martin Wabitsch; Per Bo Jensen; Werner F Blum; Claus T Christoffersen; Piera Englaro; Eberhard Heinze; Wolfgang Rascher; Walter Teller; Hans Tornqvist; Hans Hauner

Abstract

View articletitled, Insulin and Cortisol Promote Leptin Production in Cultured Human Fat Cells

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Topics: adipocytes , hydrocortisone , insulin , leptin

Diabetes October 1996, Vol.45, 1435-1438. doi:https://doi.org/10.2337/diab.45.10.1435

Cloning, Tissue Expression, and Chromosomal Localization of SUR2, the Putative Drug-Binding Subunit of Cardiac, Skeletal Muscle, and Vascular K_ATP Channels

William A Chutkow; M Celeste Simon; M Michelle Le Beau; Charles F Burant

Abstract

View articletitled, Cloning, Tissue Expression, and Chromosomal Localization of SUR2, the Putative Drug-Binding Subunit of Cardiac, Skeletal Muscle, and Vascular KATP Channels

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Topics: chromosomes , cloning , drug binding , skeletal muscles , protein isoforms

Diabetes October 1996, Vol.45, 1439-1445. doi:https://doi.org/10.2337/diab.45.10.1439

The Weight-Reducing Effect of an Intracerebroventricular Bolus Injection of Leptin in Genetically Obese fa/fa Rats: Reduced Sensitivity Compared With Lean Animals

I Cusin; Françoise Rohner-Jeanrenaud; Alain Stricker-Krongrad; Bernard Jeanrenaud

Abstract

View articletitled, The Weight-Reducing Effect of an Intracerebroventricular Bolus Injection of Leptin in Genetically Obese fa/fa Rats: Reduced Sensitivity Compared With Lean Animals

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Topics: leptin , obesity , rats

Diabetes October 1996, Vol.45, 1446-1450. doi:https://doi.org/10.2337/diab.45.10.1446

SI Units Table

Système International (SI) Units Table

View articletitled, Système International (SI) Units Table

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Diabetes October 1996, Vol.45, 1451. doi:https://doi.org/10.2337/diab.45.10.1451

Organization Section

View articletitled, Organization Section

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Diabetes October 1996, Vol.45, 1452-1453. doi:https://doi.org/10.2337/diab.45.10.1452

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Perspectives in Diabetes

The Absence of a Glycemic Threshold for the Development of Long-Term Complications: The Perspective of the Diabetes Control and Complications Trial

Diabetogenic T-Cell Clones

Original Articles

Dexamethasone-Induced Neuropeptide Y Expression in Rat Islet Endocrine Cells: Rapid Reversibility and Partial Prevention by Insulin

Effects of Glucose Ingestion Versus Infusion on Pulsatile Insulin Secretion: The Incretin Effect Is Achieved by Amplification of Insulin Secretory Burst Mass

Skeletal Muscle Content of Membrane Glycoprotein PC-1 in Obesity: Relationship to Muscle Glucose Transport

Glucosamine-Induced Inhibition of Liver Glucokinase Impairs the Ability of Hyperglycemia to Suppress Endogenous Glucose Production

Control of Islet Intercellular Adhesion Molecule-1 Expression by Interferon-α and Hypoxia

Autoantibodies to Protein Tyrosine Phosphatase-Like Proteins In Type I Diabetes: Overlapping Specificities To Phogrin And ICA512/IA-2

Both CD4⁺ and CD8⁺ T-Cells in Syngeneic Islet Grafts in NOD Mice Produce Interferon-γ During β-Cell Destruction

The β3-Adrenergic Receptor Gene Trp64Arg Mutation is Overrepresented in Obese Women: Effects on Weight, BMI, Abdominal Fat, Blood Pressure, and Reproductive History in an Elderly Australian Population

Supraphysiological Hyperinsulinemia Increases Plasma Leptin Concentrations After 4 h in Normal Subjects

Insulin Levels and the Natural History of Glucose Intolerance in Nauruans

Epinephrine Exerts Opposite Effects on Peripheral Glucose Disposal and Glucose-Stimulated Insulin Secretion: A Stable Label Intravenous Glucose Tolerance Test Minimal Model Study

Protein Tyrosine Phosphatase 1B Interacts With the Activated Insulin Receptor

High D-Glucose–Induced Changes in Endothelial Ca²⁺/EDRF Signaling are Due to Generation of Superoxide Anions

Chronic Activation of Protein Kinase C in Soleus Muscles and Other Tissues of Insulin-Resistant Type II diabetic Goto-Kakizaki (GK), Obese/Aged, and Obese/Zucker Rats: A Mechanism For Inhibiting Glycogen Synthesis

The ApoB-100 Gene EcoRI Polymorphism Influences the Relationship Between Features of the Insulin Resistance Syndrome and the Hyper-ApoB and Dense LDL Phenotype in Men

cAMP-Dependent Phosphorylation of the Cardiac-Type α1 Subunit of the Voltage-Dependent Ca²⁺ channel in a murine pancreatic β-cell line

The Rat T-Cell Surface Protein RT6 Is Associated With src Family Tyrosine Kinases and Generates an Activation Signal

Rapid Publications

Diazoxide Treatment at Onset Preserves Residual Insulin Secretion in Adults with Autoimmune Diabetes

Diadenosine Polyphosphates: A Novel Class of Glucose-Induced Intracellular Messengers in the Pancreatic β-Cell

Insulin and Cortisol Promote Leptin Production in Cultured Human Fat Cells

Cloning, Tissue Expression, and Chromosomal Localization of SUR2, the Putative Drug-Binding Subunit of Cardiac, Skeletal Muscle, and Vascular K_ATP Channels

The Weight-Reducing Effect of an Intracerebroventricular Bolus Injection of Leptin in Genetically Obese fa/fa Rats: Reduced Sensitivity Compared With Lean Animals

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Système International (SI) Units Table

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Perspectives in Diabetes

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