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Volume 45, Issue 12
1 December 1996
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ISSN 0012-1797
EISSN 1939-327X
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Perspectives in Diabetes

Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes
Alan R Saltiel; Jerrold M Olefsky
View articletitled, Thiazolidinediones in the Treatment of Insulin Resistance and Type II Diabetes
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Diabetes December 1996, Vol.45, 1661-1669. doi:https://doi.org/10.2337/diab.45.12.1661

Original Articles

Heterologous Expression and Characterization of Rat Liver Glucokinase Regulatory Protein
Kasim A Mookhtiar; Stephen S Kalinowski; Karen S Brown; Yim Ha Tsay; Constance Smith-Monroy; Gordon W Robinson
View articletitled, Heterologous Expression and Characterization of Rat Liver Glucokinase Regulatory Protein
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Diabetes December 1996, Vol.45, 1670-1677. doi:https://doi.org/10.2337/diab.45.12.1670
Abnormally Expressed Low-Voltage-Activated Calcium Channels in β-Cells From NOD Mice and a Related Clonal Cell Line
Lin Wang; Arin Bhattacharjee; Jian Fu; Ming Li
View articletitled, Abnormally Expressed Low-Voltage-Activated Calcium Channels in β-Cells From NOD Mice and a Related Clonal Cell Line
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Diabetes December 1996, Vol.45, 1678-1683. doi:https://doi.org/10.2337/diab.45.12.1678
Relationship of Generalized and Regional Adiposity to Insulin Sensitivity in Men With NIDDM
Nicola Abate; Abhimanyu Garg; Ronald M Peshock; James Stray-Gundersen; Beverley Adams-Huet; Scott M Grundy
View articletitled, Relationship of Generalized and Regional Adiposity to Insulin Sensitivity in Men With NIDDM
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Diabetes December 1996, Vol.45, 1684-1693. doi:https://doi.org/10.2337/diab.45.12.1684
Chronic Dosing With Aminoguanidine and Novel Advanced Glycosylation End Product-Formation Inhibitors Ameliorates Cross-Linking of Tail Tendon Collagen in STZ-Induced Diabetic Rats
Maral Kochakian; Belur N Manjula; John J Egan
View articletitled, Chronic Dosing With Aminoguanidine and Novel Advanced Glycosylation End Product-Formation Inhibitors Ameliorates Cross-Linking of Tail Tendon Collagen in STZ-Induced Diabetic Rats
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Diabetes December 1996, Vol.45, 1694-1700. doi:https://doi.org/10.2337/diab.45.12.1694
Identification of Two Missense Mutations in the GIP Receptor Gene: A Functional Study and Association Analysis with NIDDM: No Evidence of Association with Japanese NIDDM Subjects
Akira Kubota; Yuichiro Yamada; Tadao Hayami; Koichiro Yasuda; Yoshimichi Someya; Yu Ihara; Shinji Kagimoto; Rie Watanabe; Tomohiko Taminato; Kinsuke Tsuda; Yutaka Seino
View articletitled, Identification of Two Missense Mutations in the GIP Receptor Gene: A Functional Study and Association Analysis with NIDDM: No Evidence of Association with Japanese NIDDM Subjects
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Diabetes December 1996, Vol.45, 1701-1705. doi:https://doi.org/10.2337/diab.45.12.1701
Disease-Associated Antibodies in Offspring of Mothers with IDDM
Anu Martikainen; Tero Saukkonen; Petri K Kulmala; Helena Reijonen; Jorma Ilonen; Kari Teramo; Pentti Koskela; Mikael Knip; Hans K Åkerblom
View articletitled, Disease-Associated Antibodies in Offspring of Mothers with IDDM
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Diabetes December 1996, Vol.45, 1706-1710. doi:https://doi.org/10.2337/diab.45.12.1706
Major Histocompatibility Complex Class II Molecules Function as a Template for the Processing of a Partially Processed Insulin Peptide into a T-cell Epitope
Ying Lang; Frederique Forquet; Edwin Speck; Janice Blum; Terry L Delovitch
View articletitled, Major Histocompatibility Complex Class II Molecules Function as a Template for the Processing of a Partially Processed Insulin Peptide into a T-cell Epitope
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Diabetes December 1996, Vol.45, 1711-1719. doi:https://doi.org/10.2337/diab.45.12.1711
Interactions of Age, Islet Cell Antibodies, Insulin Autoantibodies, and First-Phase Insulin Response in Predicting Risk of Progression to IDDM in ICA+ Relatives: The ICARUS Data Set
Polly J Bingley
View articletitled, Interactions of Age, Islet Cell Antibodies, Insulin Autoantibodies, and First-Phase Insulin Response in Predicting Risk of Progression to IDDM in ICA<sup>+</sup> Relatives: The ICARUS Data Set
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Diabetes December 1996, Vol.45, 1720-1728. doi:https://doi.org/10.2337/diab.45.12.1720
Glomerular Hyperfiltration in the Prediction of Nephropathy in IDDM: A 10-Year Follow-Up Study
Jeannie W Yip; Sharon L Jones; Martin J Wiseman; Caron Hill; Giancarlo Viberti
View articletitled, Glomerular Hyperfiltration in the Prediction of Nephropathy in IDDM: A 10-Year Follow-Up Study
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Diabetes December 1996, Vol.45, 1729-1733. doi:https://doi.org/10.2337/diab.45.12.1729
Increased Hexosamine Availability Similarly Impairs the Action of Insulin and IGF-1 on Glucose Disposal
Meredith Hawkins; Nir Barzilai; Wei Chen; Ivo Angelov; Meizhu Hu; Pinchas Cohen; Luciano Rossetti
View articletitled, Increased Hexosamine Availability Similarly Impairs the Action of Insulin and IGF-1 on Glucose Disposal
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Diabetes December 1996, Vol.45, 1734-1743. doi:https://doi.org/10.2337/diab.45.12.1734
Reduced Expression of the Leptin Gene (ob) by Catecholamine Through a GS Protein-Coupled Pathway in 3T3-L1 Adipocytes
Atsushi Kosaki; Kazunori Yamada; Hideshi Kuzuya
View articletitled, Reduced Expression of the Leptin Gene (<em>ob</em>) by Catecholamine Through a G<sub>S</sub> Protein-Coupled Pathway in 3T3-L1 Adipocytes
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Diabetes December 1996, Vol.45, 1744-1749. doi:https://doi.org/10.2337/diab.45.12.1744
Immunologic Effects of Insulin Lispro [Lys (B28), Pro (B29) Human Insulin] in IDDM and NIDDM Patients Previously Treated With Insulin
Naomi S Fineberg; S Edwin Fineberg; James H Anderson; Martin A Birkett; Reid G Gibson; Suzan Hufferd
View articletitled, Immunologic Effects of Insulin Lispro [Lys (B28), Pro (B29) Human Insulin] in IDDM and NIDDM Patients Previously Treated With Insulin
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Diabetes December 1996, Vol.45, 1750-1754. doi:https://doi.org/10.2337/diab.45.12.1750
Diminished Fraction of Blockable ATP-Sensitive K+ Channels in Islets Transplanted Into Diabetic Mice
Bernat Soria; Franz Martín; Etelvina Andreu; Juan V Sanchez-Andrés; Victor Nacher; Eduard Montana
View articletitled, Diminished Fraction of Blockable ATP-Sensitive K<sup>+</sup> Channels in Islets Transplanted Into Diabetic Mice
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Diabetes December 1996, Vol.45, 1755-1760. doi:https://doi.org/10.2337/diab.45.12.1755
Tissue-Specific Self-Peptides Bound by Major Histocompatibility Complex Class I Molecules of a Human Pancreatic β-cell Line
Kyriakos P Papadopoulos; Adrianna I Colovai; Antonella Maffei; Dolores Jaraquemada; Nicole Suciu-Foca; Paul E Harris
View articletitled, Tissue-Specific Self-Peptides Bound by Major Histocompatibility Complex Class I Molecules of a Human Pancreatic β-cell Line
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Diabetes December 1996, Vol.45, 1761-1765. doi:https://doi.org/10.2337/diab.45.12.1761
The βHC-9 Pancreatic β-Cell Line Preserves the Characteristics of Progenitor Mouse Islets
Mitsuhiko Noda; Mitsuhisa Komatsu; Geoffrey W G Sharp
View articletitled, The βHC-9 Pancreatic β-Cell Line Preserves the Characteristics of Progenitor Mouse Islets
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Diabetes December 1996, Vol.45, 1766-1773. doi:https://doi.org/10.2337/diab.45.12.1766
Effects of Chronically Elevated Glucose Levels on the Functional Properties of Rat Pancreatic β-Cells
Zhidong Ling; Rita Kiekens; Tania Mahler; Frans C Schuit; Miriam Pipeleers-Marichal; Abdullah Sener; Gunther Klöppel; Willy J Malaisse; Daniel G Pipeleers
View articletitled, Effects of Chronically Elevated Glucose Levels on the Functional Properties of Rat Pancreatic β-Cells
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Diabetes December 1996, Vol.45, 1774-1782. doi:https://doi.org/10.2337/diab.45.12.1774
Dual Functional Effects of Interleukin-1β on Purine Nucleotides and Insulin Secretion in Rat Islets and INS-1 Cells
Melissa Meredith; Mary E Rabaglia; John A Corbett; Stewart A Metz
View articletitled, Dual Functional Effects of Interleukin-1β on Purine Nucleotides and Insulin Secretion in Rat Islets and INS-1 Cells
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Diabetes December 1996, Vol.45, 1783-1791. doi:https://doi.org/10.2337/diab.45.12.1783
Mechanisms of Sulfonylurea's Stimulation of Insulin Secretion In Vivo: Selective Amplification of Insulin Secretory Burst Mass
Niels K Pørksen; Stephen R Munn; Jeffery L Steers; Ole Schmitz; Johannes D Veldhuis; Peter C Butler
View articletitled, Mechanisms of Sulfonylurea's Stimulation of Insulin Secretion In Vivo: Selective Amplification of Insulin Secretory Burst Mass
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Diabetes December 1996, Vol.45, 1792-1797. doi:https://doi.org/10.2337/diab.45.12.1792
Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid: Participation of Elements of the Insulin Signaling Pathway
D Elizabeth Estrada; H Stephen Ewart; Theodoros Tsakiridis; Allen Volchuk; Toolsie Ramlal; Hans Tritschler; Amira Klip
View articletitled, Stimulation of Glucose Uptake by the Natural Coenzyme α-Lipoic Acid/Thioctic Acid: Participation of Elements of the Insulin Signaling Pathway
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Diabetes December 1996, Vol.45, 1798-1804. doi:https://doi.org/10.2337/diab.45.12.1798
In the Absence of Counterregulatory Hormones, the Increase in Hepatic Glucose Production During Insulin-Induced Hypoglycemia in the Dog Is Initiated in the Liver Rather Than the Brain
Cynthia C Connolly; Sharon R Myers; Doss W Neal; Jon R Hastings; Alan D Cherrington
View articletitled, In the Absence of Counterregulatory Hormones, the Increase in Hepatic Glucose Production During Insulin-Induced Hypoglycemia in the Dog Is Initiated in the Liver Rather Than the Brain
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Diabetes December 1996, Vol.45, 1805-1813. doi:https://doi.org/10.2337/diab.45.12.1805
Long-Term Metabolic Control by Rat Islet Grafts Depends on the Composition of the Implant
Bart Keymeulen; Greg Korbutt; Monique De Paepe; Frans Gorus; Gönter Klöppel; Daniel G Pipeleers
View articletitled, Long-Term Metabolic Control by Rat Islet Grafts Depends on the Composition of the Implant
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Diabetes December 1996, Vol.45, 1814-1821. doi:https://doi.org/10.2337/diab.45.12.1814

Rapid Publications

Troglitazone Attenuates High-Glucose–Induced Abnormalities in Relaxation and Intracellular Calcium in Rat Ventricular Myocytes
Jun Ren; Ligia J Dominguez; James R Sowers; Amy J Davidoff
View articletitled, Troglitazone Attenuates High-Glucose–Induced Abnormalities in Relaxation and Intracellular Calcium in Rat Ventricular Myocytes
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Diabetes December 1996, Vol.45, 1822-1825. doi:https://doi.org/10.2337/diab.45.12.1822
PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin
Hirotaka Watada; Yoshitaka Kajimoto; Jun-ichiro Miyagawa; Toshiaki Hanafusa; Kazuyuki Hamaguchi; Taka-aki Matsuoka; Koji Yamamoto; Yuji Matsuzawa; Ryuzo Kawamori; Yoshimitsu Yamasaki
View articletitled, PDX-1 Induces Insulin and Glucokinase Gene Expressions in αTC1 Clone 6 Cells in the Presence of Betacellulin
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Diabetes December 1996, Vol.45, 1826-1831. doi:https://doi.org/10.2337/diab.45.12.1826

Organization Section

Organization Section
View articletitled, Organization Section
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Diabetes December 1996, Vol.45, 1832-1833. doi:https://doi.org/10.2337/diab.45.12.1832

SI Units Table

Système International (SI) Units Table
View articletitled, Système International (SI) Units Table
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Diabetes December 1996, Vol.45, 1834. doi:https://doi.org/10.2337/diab.45.12.1834

1996 Subject and Author Indexes

1996 Subject and Author Indexes
View articletitled, 1996 Subject and Author Indexes
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Diabetes December 1996, Vol.45, 1835-1845. doi:https://doi.org/10.2337/diab.45.12.1835
MRI Metrics of Cerebral Endothelial Cell–Derived Exosomes for the Treatment of Cognitive Dysfunction Induced in Aging Rats Subjected to Type 2 Diabetes
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
Elevated First-Trimester Neutrophil Count Is Closely Associated With the Development of Maternal Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes
227-OR: Tirzepatide Reduces HbA1c and Body Weight Significantly More than Placebo Regardless of Insulin Sensitivity and Beta-Cell Function—Post Hoc Analysis from SURMOUNT-2
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