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1995 Presidential Address

Things Will Never Be the Same Again

Kathleen L Wishner

Abstract

View articletitled, Things Will Never Be the Same Again

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Diabetes May 1996, Vol.45, 541-543. doi:https://doi.org/10.2337/diab.45.5.541

Perspectives in Diabetes

The Search for IDDM Susceptibility Genes: The Next Generation

David Owerbach; Kenneth H Gabbay

Abstract

View articletitled, The Search for IDDM Susceptibility Genes: The Next Generation

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Topics: diabetes mellitus, type 1 , genes

Diabetes May 1996, Vol.45, 544-551. doi:https://doi.org/10.2337/diab.45.5.544

Original Articles

The Effect of Glucagon-Like Peptide I (GLP-I) on Glucose Elimination in Healthy Subjects Depends on the Pancreatic Glucoregulatory Hormones

Mai-britt Toft-Nielson; Sten Madsbad; Jens J Holst

Abstract

View articletitled, The Effect of Glucagon-Like Peptide I (GLP-I) on Glucose Elimination in Healthy Subjects Depends on the Pancreatic Glucoregulatory Hormones

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Topics: glucagon , glucose , hormones , pancreas , peptides

Diabetes May 1996, Vol.45, 552-556. doi:https://doi.org/10.2337/diab.45.5.552

Kilham Rat Virus Triggers T-Cell–Dependent Autoimmune Diabetes in Multiple Strains of Rat

Karen E Ellerman; Cindy A Richards; Dennis L Guberski; William R Shek; Arthur A Like

Abstract

View articletitled, Kilham Rat Virus Triggers T-Cell–Dependent Autoimmune Diabetes in Multiple Strains of Rat

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Topics: autoimmunity , precipitating factors , t-lymphocytes , viruses , genetic predisposition to disease

Diabetes May 1996, Vol.45, 557-562. doi:https://doi.org/10.2337/diab.45.5.557

Evidence for a Major Gene for Type II Diabetes and Linkage Analyses With Selected Candidate Genes in Mexican-Americans

Michael P Stern; Braxton D Mitchell; John Blangero; Laurie Reinhart; Candace M Krammerer; Chantal R Harrison; Patricia A Shipman; Peter O'Connell; Marsha L Frazier; Jean W MacCluer

Abstract

View articletitled, Evidence for a Major Gene for Type II Diabetes and Linkage Analyses With Selected Candidate Genes in Mexican-Americans

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Topics: candidate disease gene , diabetes mellitus, type 2 , genes

Diabetes May 1996, Vol.45, 563-568. doi:https://doi.org/10.2337/diab.45.5.563

Potentiation of Effects of Weight Loss by Monounsaturated Fatty Acids in Obese NIDDM Patients

Cecilia C Low; Eric B Grossman; Barry Gumbiner

Abstract

View articletitled, Potentiation of Effects of Weight Loss by Monounsaturated Fatty Acids in Obese NIDDM Patients

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Topics: diabetes mellitus, type 2 , monounsaturated fatty acids , obesity , potentiation , weight reduction

Diabetes May 1996, Vol.45, 569-575. doi:https://doi.org/10.2337/diab.45.5.569

Hematocrit and Risk of NIDDM

S Goya Wannamethee; Ivan J Perry; A Gerald Shaper

Abstract

View articletitled, Hematocrit and Risk of NIDDM

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Topics: diabetes mellitus, type 2 , hematocrit

Diabetes May 1996, Vol.45, 576-579. doi:https://doi.org/10.2337/diab.45.5.576

A Fatty Acid—Induced Decrease in Pyruvate Dehydrogenase Activity Is an Important Determinant of β-Cell Dysfunction in the Obese Diabetic db/db Mouse

Yun-Ping Zhou; Per-Olof Berggren; Valdemar Grill

Abstract

View articletitled, A Fatty Acid—Induced Decrease in Pyruvate Dehydrogenase Activity Is an Important Determinant of β-Cell Dysfunction in the Obese Diabetic db/db Mouse

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Topics: fatty acids , mice , obesity , pyruvate dehydrogenase (lipoamide)

Diabetes May 1996, Vol.45, 580-586. doi:https://doi.org/10.2337/diab.45.5.580

Evidence of a Glycemic Threshold for the Formation of Pentosidine in Diabetic Dog Lens but Not in Collagen

Ramanakoppa H Nagaraj; Timothy S Kern; David R Sell; John Fogarty; Ronald L Engerman; Vincent M Monnier

Abstract

View articletitled, Evidence of a Glycemic Threshold for the Formation of Pentosidine in Diabetic Dog Lens but Not in Collagen

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Topics: collagen , dog, domestic , lens (device) , lens, crystalline

Diabetes May 1996, Vol.45, 587-594. doi:https://doi.org/10.2337/diab.45.5.587

Islets of Langerhans Generate Wavelike Electric Activity Modulated by Glucose Concentration

Yoram Palti; Galia Ben David; Ela Lachov; Yuval H Mika; Gila Omri; Rachel Schatzberger

Abstract

View articletitled, Islets of Langerhans Generate Wavelike Electric Activity Modulated by Glucose Concentration

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Topics: endocrine pancreas , glucose

Diabetes May 1996, Vol.45, 595-601. doi:https://doi.org/10.2337/diab.45.5.595

The Hemodynamic Abnormalities in Short-Term Insulin Deficiency: The Role of Prostaglandin Inhibition

Angelo Avogaro; Cristina Crepaldi; Francesco Piarulli; Daniele Milan; Anna Valerio; Paola Pavan; David Sacerdoti; Alessio Calabrò; Ian Macdonald; Gaetano Crepaldi; Roldano Scognamiglio; Antonio Tiengo

Abstract

View articletitled, The Hemodynamic Abnormalities in Short-Term Insulin Deficiency: The Role of Prostaglandin Inhibition

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Topics: doppler hemodynamics , hemodynamics , insulin , prostaglandins

Diabetes May 1996, Vol.45, 602-609. doi:https://doi.org/10.2337/diab.45.5.602

Association of HLA-DPB1*0301 With IDDM in Mexican-Americans

Henry A Erlich; Jerome I Rotter; Julie D Chang; Sylvia J Shaw; Leslie J Raffel; William Klitz; Teodorica L Bugawan; Adina Zeidler

Abstract

View articletitled, Association of HLA-DPB1*0301 With IDDM in Mexican-Americans

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Topics: diabetes mellitus, type 1 , human leukocyte antigens

Diabetes May 1996, Vol.45, 610-614. doi:https://doi.org/10.2337/diab.45.5.610

Mechanisms Behind Insulin Resistance in Rat Skeletal Muscle After Oophorectomy and Additional Testosterone Treatment

Jorge Rincon; Agneta Holmäng; Erica Odegaard Wahlström; Peter Lönnroth; Per Björntorp; Juleen R Zierath; Harriet Wallberg-Henriksson

Abstract

View articletitled, Mechanisms Behind Insulin Resistance in Rat Skeletal Muscle After Oophorectomy and Additional Testosterone Treatment

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Topics: insulin resistance , ovariectomy , skeletal muscles , testosterone

Diabetes May 1996, Vol.45, 615-621. doi:https://doi.org/10.2337/diab.45.5.615

Small Doses of Subcutaneous Insulin as a Strategy for Preventing Slowly Progressive β-Cell Failure in Islet Cell Antibody—Positive Patients With Clinical Features of NIDDM

Tetsuro Kobayashi; Koji Nakanishi; Toshio Murase; Kinori Kosaka

Abstract

View articletitled, Small Doses of Subcutaneous Insulin as a Strategy for Preventing Slowly Progressive β-Cell Failure in Islet Cell Antibody—Positive Patients With Clinical Features of NIDDM

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Topics: antibodies , diabetes mellitus, type 2 , endocrine pancreas , insulin , signs and symptoms

Diabetes May 1996, Vol.45, 622-626. doi:https://doi.org/10.2337/diab.45.5.622

Diabetes Increases Sciatic Nerve Susceptibility to Endothelin-Induced Ischemia

Douglas W Zochodne; Chu Cheng; Hong Sun

Abstract

View articletitled, Diabetes Increases Sciatic Nerve Susceptibility to Endothelin-Induced Ischemia

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Topics: endothelins , ischemia , sciatic nerve

Diabetes May 1996, Vol.45, 627-632. doi:https://doi.org/10.2337/diab.45.5.627

Abdominal Fat and Insulin Resistance in Normal and Overweight Women: Direct Measurements Reveal a Strong Relationship in Subjects at Both Low and High Risk of NIDDM

David G Carey; Arthur B Jenkins; Lesley V Campbell; Judith Freund; Donald J Chisholm

Abstract

View articletitled, Abdominal Fat and Insulin Resistance in Normal and Overweight Women: Direct Measurements Reveal a Strong Relationship in Subjects at Both Low and High Risk of NIDDM

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Topics: abdomen , diabetes mellitus, type 2 , insulin resistance , overweight

Diabetes May 1996, Vol.45, 633-638. doi:https://doi.org/10.2337/diab.45.5.633

Mitochondrial FAD-Glycerophosphate Dehydrogenase and G-Protein—Coupled Inwardly Rectifying K⁺ Channel: No Evidence for Linkage in Maturity-Onset Diabetes of the Young or NIDDM

Margaret G Warren-Perry; Markus Stoffel; Philip J Saker; Yun Zhang; Louise J Brown; Michael J MacDonald; Robert C Turner

Abstract

View articletitled, Mitochondrial FAD-Glycerophosphate Dehydrogenase and G-Protein—Coupled Inwardly Rectifying K+ Channel: No Evidence for Linkage in Maturity-Onset Diabetes of the Young or NIDDM

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Topics: diabetes mellitus, type 2 , glycerophosphates , gtp-binding proteins , maturity onset diabetes mellitus in young , mitochondria

Diabetes May 1996, Vol.45, 639-641. doi:https://doi.org/10.2337/diab.45.5.639

LY290181, an Inhibitor of Diabetes-Induced Vascular Dysfunction, Blocks Protein Kinase C—Stimulated Transcriptional Activation Through Inhibition of Transcription Factor Binding to a Phorbol Response Element

Kimberly A Birch; William F Heath; Ronald N Hermeling; Cecile M Johnston; Larry Stramm; Colin Dell; Colin Smith; Joseph R Williamson; Anne Reifel-Miller

Abstract

View articletitled, LY290181, an Inhibitor of Diabetes-Induced Vascular Dysfunction, Blocks Protein Kinase C—Stimulated Transcriptional Activation Through Inhibition of Transcription Factor Binding to a Phorbol Response Element

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Topics: phorbols , protein kinase c , response elements , transcription inhibition , transcriptional activation

Diabetes May 1996, Vol.45, 642-650. doi:https://doi.org/10.2337/diab.45.5.642

Metabolic Impairment Precedes Insulin Resistance in Skeletal Muscle During High-Fat Feeding in Rats

Jason K Kim; Jae K Wi; Jang H Youn

Abstract

View articletitled, Metabolic Impairment Precedes Insulin Resistance in Skeletal Muscle During High-Fat Feeding in Rats

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Topics: insulin resistance , rats , skeletal muscles

Diabetes May 1996, Vol.45, 651-658. doi:https://doi.org/10.2337/diab.45.5.651

Oral Vanadyl Sulfate Improves Insulin Sensitivity in NIDDM but Not in Obese Nondiabetic Subjects

Meyer Halberstam; Neil Cohen; Pavel Shlimovich; Luciano Rossetti; Harry Shamoon

Abstract

View articletitled, Oral Vanadyl Sulfate Improves Insulin Sensitivity in NIDDM but Not in Obese Nondiabetic Subjects

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Topics: diabetes mellitus, type 2 , insulin sensitivity , obesity , sulfate

Diabetes May 1996, Vol.45, 659-666. doi:https://doi.org/10.2337/diab.45.5.659

Increased Urea Synthesis in Insulin-Dependent Diabetic Dogs Maintained Normoglycemic: Effect of Portal Insulin Administration and Food Protein Content

E-J Freyse; K Rebrin; T Schneider; M Petrzika; U Fischer

Abstract

View articletitled, Increased Urea Synthesis in Insulin-Dependent Diabetic Dogs Maintained Normoglycemic: Effect of Portal Insulin Administration and Food Protein Content

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Topics: blood glucose normal , dog, domestic , insulin , insulin administration , urea

Diabetes May 1996, Vol.45, 667-674. doi:https://doi.org/10.2337/diab.45.5.667

Human Obese Gene: Molecular Screening in Japanese and Asian Indian NIDDM Patients Associated With Obesity

Toshiharu Niki; Hiroyuki Mori; Yoshikazu Tamori; Miyako Kishimoto-Hashirmoto; Hirohisa Ueno; Satoshi Araki; Jiro Masugi; Nitin Sawant; Hemali R Majithia; Nadeem Rais; Mitsuru Hashiramoto; Hiroshi Taniguchi; Masato Kasuga

Abstract

View articletitled, Human Obese Gene: Molecular Screening in Japanese and Asian Indian NIDDM Patients Associated With Obesity

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Topics: diabetes mellitus, type 2 , genes , obesity , screening

Diabetes May 1996, Vol.45, 675-678. doi:https://doi.org/10.2337/diab.45.5.675

Rapid Publications

Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects

Margherita Maffei; Markus Stoffel; Marisa Barone; Byoung Moon; Marilyn Dammerman; Eric Ravussin; Clifton Bogardus; David S Ludwig; Jeffrey S Flier; Matchugo Talley; Stephen Auerbach; Jeffrey M Friedman

Abstract

View articletitled, Absence of Mutations in the Human OB Gene in Obese/Diabetic Subjects

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Topics: genes , mutation , obesity

Diabetes May 1996, Vol.45, 679-682. doi:https://doi.org/10.2337/diab.45.5.679

Association Between Insulin Secretory Pulse Frequency and Peripheral Insulin Action in NIDDM and Normal Subjects

Steven J Hunter; A Brew Atkinson; Cieran N Ennis; Brian Sheridan; Patrick M Bell

Abstract

View articletitled, Association Between Insulin Secretory Pulse Frequency and Peripheral Insulin Action in NIDDM and Normal Subjects

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Topics: diabetes mellitus, type 2 , insulin , pulse

Diabetes May 1996, Vol.45, 683-686. doi:https://doi.org/10.2337/diab.45.5.683

Indication for Linkage of the Human OB Gene Region With Extreme Obesity

Karine Clement; Chad Garner; Jorg Hager; Anne Philippi; Carrie LeDuc; Alisoun Carey; Timothy JR Harris; Corinne Jury; Lon R Cardon; Arnaud Basdevant; Florence Demenais; Bernard Guy-Grand; Michael North; Philippe Froguel

Abstract

View articletitled, Indication for Linkage of the Human OB Gene Region With Extreme Obesity

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Topics: genes , obesity, morbid

Diabetes May 1996, Vol.45, 687-690. doi:https://doi.org/10.2337/diab.45.5.687

Extreme Obesity May Be Linked to Markers Flanking the Human OB Gene

Danielle R Reed; Yuan Ding; Weizhen Xu; Corinne Cather; Eric D Green; R Arlen Price

Abstract

View articletitled, Extreme Obesity May Be Linked to Markers Flanking the Human OB Gene

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Topics: genes , obesity, morbid

Diabetes May 1996, Vol.45, 691-694. doi:https://doi.org/10.2337/diab.45.5.691

Plasma Leptin and Insulin Relationships in Obese and Nonobese Humans

Samuel Dagogo-Jack; Carmine Fanelli; Deanna Paramore; Joy Brothers; Michael Landt

Abstract

View articletitled, Plasma Leptin and Insulin Relationships in Obese and Nonobese Humans

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Topics: insulin , leptin , obesity , plasma

Diabetes May 1996, Vol.45, 695-698. doi:https://doi.org/10.2337/diab.45.5.695

Acute and Chronic Effect of Insulin on Leptin Production in Humans: Studies In Vivo and In Vitro

Jerzy W Kolaczynski; Mark R Nyce; Robert V Considine; Guenther Boden; John J Nolan; Robert Henry; Sunder R Mudaliar; Jerrold Olefsky; Jose F Caro

Abstract

View articletitled, Acute and Chronic Effect of Insulin on Leptin Production in Humans: Studies In Vivo and In Vitro

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Topics: insulin , leptin

Diabetes May 1996, Vol.45, 699-701. doi:https://doi.org/10.2337/diab.45.5.699

Organization Section

View articletitled, Organization Section

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Diabetes May 1996, Vol.45, 702-703. doi:https://doi.org/10.2337/diab.45.5.702

SI Units Table

View articletitled, SI Units Table

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Diabetes May 1996, Vol.45, 704. doi:https://doi.org/10.2337/diab.45.5.704

Issues

1995 Presidential Address

Perspectives in Diabetes

Original Articles

Rapid Publications

Organization Section

SI Units Table

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