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1 March 1997
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ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
The Mystery of Diabetes and Atherosclerosis: Time for a New Plot
Topics:
atherosclerosis
Diabetes March 1997, Vol.46, 327-334. doi:https://doi.org/10.2337/diab.46.3.327
Original Articles
Interactions Between Leptin and Hypothalamic Neuropeptide Y Neurons in the Control of Food Intake and Energy Homeostasis in the Rat
Qiong Wang; Chen Bing; Kamal Al-Barazanji; Danuta E Mossakowaska; Xin-Min Wang; Diane L McBay; William A Neville; Mohammad Taddayon; Lucy Pickavance; Simon Dryden; Moira E A Thomas; Mark T McHale; Israel S Gloyer; Shelagh Wilson; Robin Buckingham; Jonathan R S Arch; Paul Trayhurn; Gareth Williams
Topics:
eating
,
homeostasis
,
hypothalamus
,
leptin
,
neurons
Diabetes March 1997, Vol.46, 335-341. doi:https://doi.org/10.2337/diab.46.3.335
Depot- and Sex-Specific Differences in Human Leptin mRNA Expression: Implications for the Control of Regional Fat Distribution
Topics:
body fat distribution
,
leptin
,
rna, messenger
Diabetes March 1997, Vol.46, 342-347. doi:https://doi.org/10.2337/diab.46.3.342
Improved Insulin Sensitivity by Bezafibrate in Rats: Relationship to Fatty Acid Composition of Skeletal-Muscle Triglycerides
Topics:
bezafibrate
,
fatty acids
,
insulin sensitivity
,
rats
,
skeletal muscles
Diabetes March 1997, Vol.46, 348-353. doi:https://doi.org/10.2337/diab.46.3.348
Cell-Specific Regulation of IRS-1 Gene Expression: Role of E Box and C/EBP Binding Site in HepG2 Cells and CHO Cells
Kohji Matsuda; Eiichi Araki; Ryohei Yoshimura; Kaku Tsuruzoe; Noboru Furukawa; Kengo Kaneko; Hiroyuki Motoshima; Kazuaki Yoshizato; Kishikawa Hideki; Motoaki Shichiri
Topics:
binding sites
,
cho cells
,
evidence-based practice
,
gene expression
,
irs1 protein, human
Diabetes March 1997, Vol.46, 354-362. doi:https://doi.org/10.2337/diab.46.3.354
New Monoclonal Antibody Diagnostic Reagents for Type I Diabetes: Differential Lymphocyte Surface Antigen Expression Related to Disease
Diabetes March 1997, Vol.46, 363-371. doi:https://doi.org/10.2337/diab.46.3.363
Insulin Resistance Prevented by Portal Delivery of Insulin in Rats With Renal Subcapsular Islet Grafts
Topics:
insulin
,
insulin resistance
,
kidney
,
rats
,
tissue transplants
Diabetes March 1997, Vol.46, 372-378. doi:https://doi.org/10.2337/diab.46.3.372
MHC Class II–Dependent Abnormal Reactivity Toward Bacterial Superantigens in Immune Cells of NOD Mice
Topics:
genes, mhc class ii
,
mice, inbred nod
,
superantigens
Diabetes March 1997, Vol.46, 379-385. doi:https://doi.org/10.2337/diab.46.3.379
Mapping Novel Pancreatic Islet Genes to Human Chromosomes
Jorge Ferrer; Jonathon Wasson; Kathleen D Schoor; Michael Mueckler; Helen Donis-Keller; M Alan Permutt
Topics:
chromosomes, human
,
endocrine pancreas
,
genes
,
dna, complementary
Diabetes March 1997, Vol.46, 386-392. doi:https://doi.org/10.2337/diab.46.3.386
Long-Chain Fatty Acids Inhibit Acetyl-CoA Carboxylase Gene Expression in the Pancreatic β-Cell Line INS-1
Topics:
acetyl-coa carboxylase
,
fatty acids
,
gene expression
,
pancreas
Diabetes March 1997, Vol.46, 393-400. doi:https://doi.org/10.2337/diab.46.3.393
The α2-Adrenergic Receptor Is More Effective Than the Galanin Receptor in Activating G-Proteins in RINm5F β-cell Membranes
Topics:
galanin
,
gtp-binding proteins
,
tissue membrane
Diabetes March 1997, Vol.46, 401-407. doi:https://doi.org/10.2337/diab.46.3.401
Increased Lipogenic Capacity of the Islets of Obese Rats: A Role in the Pathogenesis of NIDDM
Topics:
diabetes mellitus, type 2
,
obesity
,
rats
Diabetes March 1997, Vol.46, 408-413. doi:https://doi.org/10.2337/diab.46.3.408
Effects of Multiple Daily Insulin Injections and Intraperitoneal Insulin Therapy on Cholesteryl Ester Transfer and Lipoprotein Lipase Activities in NIDDM
Topics:
cholesterol esters
,
diabetes mellitus, type 2
,
insulin
,
insulin administration
,
intraperitoneal infusion
Diabetes March 1997, Vol.46, 414-420. doi:https://doi.org/10.2337/diab.46.3.414
Impaired Basal Glucose Effectiveness in NIDDM: Contribution of Defects in Glucose Disappearance and Production, Measured Using an Optimized Minimal Model Independent Protocol
Ananda Basu; Andrea Caumo; Francesca Bettini; Anna Gelisio; Aus Alzaid; Claudio Cobelli; Robert A Rizza
Topics:
diabetes mellitus, type 2
,
glucose
Diabetes March 1997, Vol.46, 421-432. doi:https://doi.org/10.2337/diab.46.3.421
Cardiac and Glycemic Benefits of Troglitazone Treatment in NIDDM
Mahmoud N Ghazzi; Julio E Perez; Tammy K Antonucci; Joseph H Driscoll; Saling M Huang; Barbara W Faja; The Troglitazone Study Group; Randall W Whitcomb
Topics:
diabetes mellitus, type 2
,
troglitazone
Diabetes March 1997, Vol.46, 433-439. doi:https://doi.org/10.2337/diab.46.3.433
Insulin Lispro in CSII: Results of a Double-Blind Crossover Study
Topics:
insulin lispro
Diabetes March 1997, Vol.46, 440-450. doi:https://doi.org/10.2337/diab.46.3.440
Muscle Rad Expression and Human Metabolism: Potential Role of the Novel Ras-Related GTPase in Energy Expenditure and Body Composition
W Timothy Garvey; Lidia Maianu; Adele Kennedy; Penny Wallace; Elizabeth Ganaway; Lawrence L Hamacher; David P Yarnall; James M Lenhard; Daniel K Burns
Topics:
body composition
,
energy metabolism
,
guanosine triphosphate phosphohydrolases
,
metabolism
Diabetes March 1997, Vol.46, 444-450. doi:https://doi.org/10.2337/diab.46.3.444
Differential Regulation of the p80 Tumor Necrosis Factor Receptor in Human Obesity and Insulin Resistance
Topics:
insulin resistance
,
obesity
,
tumor necrosis factor receptor
Diabetes March 1997, Vol.46, 451-455. doi:https://doi.org/10.2337/diab.46.3.451
Visceral Fat and Race-Dependent Health Risks in Obese Nondiabetic Premenopausal Women
Topics:
obesity
,
premenopause
,
visceral fat
Diabetes March 1997, Vol.46, 456-462. doi:https://doi.org/10.2337/diab.46.3.456
The Receptor for Advanced Glycation End Products Mediates the Chemotaxis of Rabbit Smooth Muscle Cells
Takayuki Higashi; Hiroyuki Sano; Tetsushi Saishoji; Kazuyoshi Ikeda; Yoshiteru Jinnouchi; Tetsuto Kanzaki; Nobuhiro Morisaki; Heikki Rauvala; Motoaki Shichiri; Seikoh Horiuchi
Topics:
myocytes, smooth muscle
,
oryctolagus cuniculus
,
receptor for advanced glycation endproducts
Diabetes March 1997, Vol.46, 463-472. doi:https://doi.org/10.2337/diab.46.3.463
Expression of Transforming Growth Factor-β and Type IV Collagen in Early Streptozotocin-Induced Diabetes
Topics:
collagen type iv
,
streptozocin
Diabetes March 1997, Vol.46, 473-480. doi:https://doi.org/10.2337/diab.46.3.473
Differences Between Nisoldipine and Lisinopril on Glomerular Filtration Rates and Albuminuria in Hypertensive IDDM Patients With Diabetic Nephropathy During the First Year of Treatment
Peter Rossing; Lise Tarnow; Søren Boelskifte; Berit R Jensen; Flemming S Nielsen; Hans-Henrik Parving
Topics:
albuminuria
,
diabetes mellitus, type 1
,
diabetic nephropathy
,
glomerular filtration rate
,
hypertension
Diabetes March 1997, Vol.46, 481-487. doi:https://doi.org/10.2337/diab.46.3.481
Phosphorylation of Myosin Light Chain in Resting Platelets From NIDDM Patients Is Enhanced: Correlation With Spontaneous Aggregation
Koichiro Fukuda; Yukio Ozaki; Kaneo Satoh; Shoji Kume; Masato Tawata; Toshimasa Onaya; Katsuhiko Sakurada; Minoru Seto; Yasuharu Sasaki
Diabetes March 1997, Vol.46, 488-493. doi:https://doi.org/10.2337/diab.46.3.488
Identification of a Common Amino Acid Polymorphism in the p85α Regulatory Subunit of Phosphatidylinositol 3-Kinase: Effects on Glucose Disappearance Constant, Glucose Effectiveness, and the Insulin Sensitivity Index
Torben Hansen; Carsten B Andersen; Søren M Echwald; Søren A Urhammer; Jesper O Clausen; Henrik Vestergaard; David Owens; Lars Hansen; Oluf Pedersen
Topics:
1-phosphatidylinositol 3-kinase
,
amino acids
,
glucose
,
insulin sensitivity
,
polymorphism
Diabetes March 1997, Vol.46, 494-501. doi:https://doi.org/10.2337/diab.46.3.494
Sequence Variants in the Pancreatic Islet β-Cell Inwardly Rectifying K+ Channel Kir6.2 (Bir) Gene: Identification and Lack of Role in Caucasian Patients with NIDDM
Hiroshi Inoue; Jorge Ferrer; Margaret Warren-Perry; Yun Zhang; Helen Millns; Robert C Turner; Steven C Elbein; Carol L Hampe; Brian K Suarez; Nobuya Inagaki; Susumu Seino; M Alan Permutt
Topics:
diabetes mellitus, type 2
,
endocrine pancreas
,
genes
Diabetes March 1997, Vol.46, 502-507. doi:https://doi.org/10.2337/diab.46.3.502
Amino Acid Polymorphisms in the ATP-Regulatable Inward Rectifier Kir6.2 and Their Relationships to Glucose- and Tolbutamide-Induced Insulin Secretion, the Insulin Sensitivity Index, and NIDDM
Topics:
amino acids
,
diabetes mellitus, type 2
,
glucose
,
insulin secretion
,
insulin sensitivity
Diabetes March 1997, Vol.46, 508-512. doi:https://doi.org/10.2337/diab.46.3.508
Mutations in the Hepatocyte Nuclear Factor-1α Gene in MODY and Early-Onset NIDDM: Evidence for a Mutational Hotspot in Exon 4
Pamela J Kaisaki; Stephan Menzel; Tom Lindner; Naohisa Oda; Ilona Rjasanowski; Jürgen Sahm; Gustav Meincke; Jan Schulze; Harald Schmechel; Cornelia Petzold; Hellmuth M Ledermann; Günther Sachse; V Vicky Boriraj; Ruth Menzel; Wolfgang Kerner; Robert C Turner; Kazuya Yamagata; Graeme I Bell
Topics:
diabetes mellitus, type 2
,
exons
,
genes
,
hepatocytes
,
maturity onset diabetes mellitus in young
Diabetes March 1997, Vol.46, 528-535. doi:https://doi.org/10.2337/diab.46.3.528
Rapid Publications
Phenotype of the Obese Koletsky (f) Rat Due to Tyr763Stop Mutation in the Extracellular Domain of the Leptin Receptor (Lepr): Evidence for Deficient Plasma-to-CSF Transport of Leptin in Both the Zucker and Koletsky Obese Rat
X Sharon Wu-Peng; Streamson C Chua, Jr; Norichika Okada; Shun-Mei Liu; Margery Nicolson; Rudolph L Leibel
Topics:
cerebrospinal fluid
,
leptin
,
mutation
,
obesity
,
phenotype
Diabetes March 1997, Vol.46, 513-518. doi:https://doi.org/10.2337/diab.46.3.513
Trehalose: A Cryoprotectant That Enhances Recovery and Preserves Function of Human Pancreatic Islets After Long-Term Storage
Topics:
cryoprotective agents
,
endocrine pancreas
,
trehalose
Diabetes March 1997, Vol.46, 519-523. doi:https://doi.org/10.2337/diab.46.3.519
Insulin Receptor Substrate-1 Phosphorylation and Phosphatidylinositol 3-Kinase Activity in Skeletal Muscle From NIDDM Subjects After In Vivo Insulin Stimulation
Topics:
1-phosphatidylinositol 3-kinase
,
diabetes mellitus, type 2
,
insulin
,
insulin receptor
,
phosphorylation
Diabetes March 1997, Vol.46, 524-527. doi:https://doi.org/10.2337/diab.46.3.524
Erratum
Organization Section
Organization Section
Diabetes March 1997, Vol.46, 538-539. doi:https://doi.org/10.2337/diab.46.3.538
