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1 May 1997
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ISSN 0012-1797
EISSN 1939-327X
Original Articles
Differential Activation of Mitogen-Activated Protein Kinase by Insulin and Epidermal Growth Factor in 3T3-L1 Adipocytes: A Possible Involvement of PI3-Kinase in the Activation of the MAP Kinase by Insulin
Junko Suga; Yasunao Yoshimasa; Kazunori Yamada; Yuji Yamamoto; Gen Inoue; Motozumi Okamoto; Tatsuya Hayashi; Michika Shigemoto; Atsushi Kosaki; Hideshi Kuzuya; Kazuwa Nakao
Topics:
1-phosphatidylinositol 3-kinase
,
adipocytes
,
epidermal growth factor
,
insulin
,
mitogen-activated protein kinases
Diabetes May 1997, Vol.46, 735-741. doi:https://doi.org/10.2337/diab.46.5.735
Insulin Stimulates Nitric Oxide Synthesis in Human Platelets and, Through Nitric Oxide, Increases Platelet Concentrations of Both Guanosine-3′, 5′-Cyclic Monophosphate and Adenosine-3′, 5′-Cyclic Monophosphate
Mariella Trovati; Giovanni Anfossi; Paola Massucco; Luigi Mattiello; Costanzo Costamagna; Valentina Piretto; Elena Mularoni; Franco Cavalot; Amalia Bosia; Dario Ghigo
Topics:
adenosine
,
blood platelets
,
guanosine
,
insulin
,
nitric oxide
Diabetes May 1997, Vol.46, 742-749. doi:https://doi.org/10.2337/diab.46.5.742
Apoptosis Is the Mode of β-Cell Death Responsible for the Development of IDDM in the Nonobese Diabetic (NOD) Mouse
Topics:
apoptosis
,
diabetes mellitus, type 1
,
mice
Diabetes May 1997, Vol.46, 750-757. doi:https://doi.org/10.2337/diab.46.5.750
Hsp60 Peptide Therapy of NOD Mouse Diabetes Induces a Th2 Cytokine Burst and Downregulates Autoimmunity to Various β-Cell Antigens
Dana Elias; Aviram Meilin; Vitaly Ablamunits; Ohad S Birk; Pnina Carmi; Stephanie Könen-Waisman; Irun R Cohen
Topics:
antigens
,
autoimmunity
,
chaperonin 60
,
cytokine
,
mice, inbred nod
Diabetes May 1997, Vol.46, 758-765. doi:https://doi.org/10.2337/diab.46.5.758
Rejection of Islets Differing by a Single Antigen Is Dependent on Donor MHC
Murielle Vigneau-Hermellin; Letizia Vitali; Isabelle Tardivel; Myriam Rabaud; Michael V Holers; Jean-Claude Carel
Topics:
antigens
,
donors
,
rejection (psychology)
Diabetes May 1997, Vol.46, 765-769. doi:https://doi.org/10.2337/diab.46.5.765
Interferon-γ Independently Activates the MHC Class I Antigen Processing Pathway and Diminishes Glucose Responsiveness in Pancreatic β-Cell Lines
Topics:
glucose
,
histocompatibility antigens class i
,
human leukocyte interferon
,
interferons
,
pancreas
Diabetes May 1997, Vol.46, 770-778. doi:https://doi.org/10.2337/diab.46.5.770
Effect of MHC Transgene Expression on Spontaneous Insulin Autoantibody Class Switch in Nonobese Diabetic Mice
Topics:
autoantibodies
,
insulin
,
mice, inbred nod
,
transgenes
Diabetes May 1997, Vol.46, 779-784. doi:https://doi.org/10.2337/diab.46.5.779
Insulinotropic Glucagon-Like Peptide I Receptor Expression in Glucagon-Producing α-Cells of the Rat Endocrine Pancreas
Topics:
endocrine pancreas
,
glucagon
,
peptides
Diabetes May 1997, Vol.46, 785-791. doi:https://doi.org/10.2337/diab.46.5.785
Glucagon-Like Peptide I and Glucose-Dependent Insulinotropic Polypeptide Stimulate Ca2+-Induced Secretion in Rat α-Cells by a Protein Kinase A–Mediated Mechanism
Topics:
bodily secretions
,
cyclic amp-dependent protein kinases
,
glucagon
,
glucose
,
peptides
Diabetes May 1997, Vol.46, 792-800. doi:https://doi.org/10.2337/diab.46.5.792
Activation of Autonomic Nerves and the Adrenal Medulla Contributes to Increased Glucagon Secretion During Moderate Insulin-Induced Hypoglycemia in Women
Topics:
adrenal medulla
,
autonomic nervous system
,
glucagon secretion
,
hypoglycemia
,
insulin
Diabetes May 1997, Vol.46, 801-807. doi:https://doi.org/10.2337/diab.46.5.801
Parallel Reduction of Pancreas Insulin Content and Insulin Secretion in 48-h Tolbutamide-Infused Normoglycemic Rats
Topics:
blood glucose normal
,
insulin
,
insulin secretion
,
pancreas
,
rats
Diabetes May 1997, Vol.46, 808-813. doi:https://doi.org/10.2337/diab.46.5.808
Contribution of Autonomic Neuropathy to Reduced Plasma Adrenaline Responses to Hypoglycemia in IDDM: Evidence for a Nonselective Defect
Paolo Bottini; Enrico Boschetti; Simone Pampanelli; Marco Ciofetta; Paola Del Sindaco; Luciano Scionti; Paolo Brunetti; Geremia B Bolli
Topics:
autonomic neuropathy
,
diabetes mellitus, type 1
,
epinephrine
,
hypoglycemia
,
plasma
Diabetes May 1997, Vol.46, 814-823. doi:https://doi.org/10.2337/diab.46.5.814
Blood Glucose Lowering and Glucagonostatic Effects of Glucagon-Like Peptide I in Insulin-Deprived Diabetic Dogs
Topics:
blood glucose
,
dog, domestic
,
glucagon
,
insulin
,
peptides
Diabetes May 1997, Vol.46, 824-828. doi:https://doi.org/10.2337/diab.46.5.824
Importance of Cerebral Blood Flow to the Recognition of and Physiological Responses to Hypoglycemia
Topics:
cerebral blood flow
,
hypoglycemia
Diabetes May 1997, Vol.46, 829-833. doi:https://doi.org/10.2337/diab.46.5.829
Regulation of Glomerular Epithelial Cell Production of Fibronectin and Transforming Growth Factor-β by High Glucose, Not by Angiotensin II
Nicole F van Det; Nicole A M Verhagen; Jouke T Tamsma; Jo H M Berden; Jan A Bruijn; Mohamed R Daha; Fokko J van der Woude
Topics:
angiotensin ii
,
epithelial cells
,
fibronectins
,
glucose
,
kidney glomerulus
Diabetes May 1997, Vol.46, 834-840. doi:https://doi.org/10.2337/diab.46.5.834
Binding Properties of Glutamate Receptors in Streptozotocin-Induced Diabetes in Rats
Gagné Joël; Martin Milot; Sylvie Gélinas; Ahmed Lahsaïni; François Trudeau; Maria-Grazia Martinoli; Guy Massicotte
Topics:
glutamate receptors
,
rats
,
streptozocin
Diabetes May 1997, Vol.46, 841-846. doi:https://doi.org/10.2337/diab.46.5.841
Mitogen-Activated Protein Kinase Cascade Is Activated in Glomeruli of Diabetic Rats and Glomerular Mesangial Cells Cultured Under High Glucose Conditions
Topics:
glucose
,
kidney glomerulus
,
mesangial cells
,
mitogen-activated protein kinases
,
rats
Diabetes May 1997, Vol.46, 847-853. doi:https://doi.org/10.2337/diab.46.5.847
Increased Renal Production of Transforming Growth Factor-β1 in Patients with Type II Diabetes
Kumar Sharma; Fuad N Ziyadeh; Bashar Alzahabi; Tracy A McGowan; Shiv Kapoor; Brenda R C Kurnik; Peter B Kurnik; Lawernce S Weisberg
Topics:
diabetes mellitus, type 2
,
kidney
Diabetes May 1997, Vol.46, 854-859. doi:https://doi.org/10.2337/diab.46.5.854
Effect of Insulin on Systemic and Renal Handling of Albumin in Nondiabetic and NIDDM Subjects
Carlo Catalano; Elsa Muscelli; Alfredo Quiñones Galvan; Simona Baldi; Antonio Masoni; Ian Gibb; Ole Torffvit; Giuseppe Seghieri; Ele Ferrannini
Topics:
albumins
,
diabetes mellitus, type 2
,
insulin
,
kidney
Diabetes May 1997, Vol.46, 868-875. doi:https://doi.org/10.2337/diab.46.5.868
New Susceptibility Locus for NIDDM Is Localized to Human Chromosome 20q
Topics:
chromosomes, human
,
diabetes mellitus, type 2
Diabetes May 1997, Vol.46, 876-881. doi:https://doi.org/10.2337/diab.46.5.876
Linkage of Genetic Markers on Human Chromosomes 20 and 12 to NIDDM in Caucasian Sib Pairs With a History of Diabetic Nephropathy
Donald W Bowden; Michèle Sale; Timothy D Howard; Asif Qadri; Beverly J Spray; Cynthia B Rothschild; Gita Akots; Stephen S Rich; Barry I Freedman
Diabetes May 1997, Vol.46, 882-886. doi:https://doi.org/10.2337/diab.46.5.882
A Novel Locus, Mody4, Distal to D7Mit189 on Chromosome 7 Determines Early-Onset NIDDM in Nonobese C57BL/6 (Akita) Mutant Mice
Diabetes May 1997, Vol.46, 887-894. doi:https://doi.org/10.2337/diab.46.5.887
Rapid Publications
Progression of Nephropathy in Spontaneous Diabetic Rats Is Prevented by OPB-9195, a Novel Inhibitor of Advanced Glycation
Sakurako Nakamura; Zenji Makita; Shintaro Ishikawa; Koichi Yasumura; Wataru Fujii; Katsuyuki Yanagisawa; Tetsuya Kawata; Takao Koike
Topics:
glycation
,
kidney diseases
,
rats
Diabetes May 1997, Vol.46, 895-899. doi:https://doi.org/10.2337/diab.46.5.895
Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis
Ruth E Gimeno; Marlene Dembski; Xun Weng; Nanhua Deng; Andrew W Shyjan; Carlos J Gimeno; Francois Iris; Stephen J Ellis; Elizabeth A Woolf; Louis A Tartaglia
Topics:
cloning
,
mitochondrial uncoupling proteins
,
thermogenesis
Diabetes May 1997, Vol.46, 900-906. doi:https://doi.org/10.2337/diab.46.5.900
Development of Autoimmune Diabetes in NOD Mice Is Associated With the Formation of Peroxynitrite in Pancreatic Islet β-Cells
Topics:
autoimmunity
,
endocrine pancreas
,
mice, inbred nod
,
peroxynitrite
Diabetes May 1997, Vol.46, 907-911. doi:https://doi.org/10.2337/diab.46.5.907
A Prevalent Amino Acid Polymorphism at Codon 98 in the Hepatocyte Nuclear Factor-1α Gene Is Associated With Reduced Serum C-Peptide and Insulin Responses to an Oral Glucose Challenge
Søen A Urhammer; Marianne Fridberg; Torben Hansen; Søren K Rasmussen; Ann Merete Møller; Jesper O Clausen; Oluf Pedersen
Topics:
amino acids
,
codon nucleotides
,
c-peptide
,
genes
,
glucose
Diabetes May 1997, Vol.46, 912-916. doi:https://doi.org/10.2337/diab.46.5.912
Leptin Is Present in Human Cord Blood
Topics:
leptin
,
umbilical cord blood
Diabetes May 1997, Vol.46, 917-919. doi:https://doi.org/10.2337/diab.46.5.917
Increased Prevalence of Mitochondrial DNA Deletions in Skeletal Muscle of Older Individuals With Impaired Glucose Tolerance: Possible Marker of Glycemic Stress
Topics:
dna, mitochondrial
,
glucose intolerance
,
older adult
,
skeletal muscles
,
stress
Diabetes May 1997, Vol.46, 920-924. doi:https://doi.org/10.2337/diab.46.5.920
Errata
SI Units Table
Système International (SI) Units Table
Diabetes May 1997, Vol.46, 925. doi:https://doi.org/10.2337/diab.46.5.925
