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Original Articles
Impact of Natural IRS-1 Mutations on Insulin Signals: Mutations of IRS-1 in the PTB Domain and Near SH2 Protein Binding Sites Result in Impaired Function at Different Steps of IRS-1 Signaling
Ryohei Yoshimura; Eiichi Araki; Sachiko Ura; Mikio Todaka; Kaku Tsuruzoe; Furukawa Noboru; Hiroyuki Motoshima; Kazuaki Yoshizato; Kengo Kaneko; Kohji Matsuda; Hideki Kishikawa; Motoaki Shichiri
Topics:
insulin
,
irs1 protein, human
,
mutation
,
protein binding
,
signal transduction
Diabetes June 1997, Vol.46, 929-936. doi:https://doi.org/10.2337/diab.46.6.929
Treatment With Neutralizing Antibodies Specific for IL-1β Prevents Cyclophosphamide-Induced Diabetes in Nonobese Diabetic Mice
Topics:
cyclophosphamide
,
mice, inbred nod
,
neutralizing antibodies
Diabetes June 1997, Vol.46, 937-940. doi:https://doi.org/10.2337/diab.46.6.937
B-Cells Are Required for the Initiation of Insulitis and Sialitis in Nonobese Diabetic Mice
Topics:
b-lymphocytes
,
mice, inbred nod
,
sialadenitis
Diabetes June 1997, Vol.46, 941-946. doi:https://doi.org/10.2337/diab.46.6.941
Islet Capillary Blood Pressure Increase Mediated by Hyperglycemia in NIDDM GK Rats
Topics:
blood capillaries
,
blood pressure
,
diabetes mellitus, type 2
,
hyperglycemia
,
rats
Diabetes June 1997, Vol.46, 947-952. doi:https://doi.org/10.2337/diab.46.6.947
Characterization of the Unusual Insulin of Psammomys obesus, a Rodent With Nutrition-Induced NIDDM-Like Syndrome
Nurit Kaiser; Elaine M Bailyes; Bruce S Schneider; Erol Cerasi; Donald F Steiner; John C Hutton; David J Gross
Topics:
diabetes mellitus, type 2
,
insulin
,
rodentia
,
science of nutrition
Diabetes June 1997, Vol.46, 953-957. doi:https://doi.org/10.2337/diab.46.6.953
Novel Insulinoma Cell Lines Produced by Iterative Engineering of GLUT2, Glucokinase, and Human Insulin Expression
Samuel A Clark; Christian Quaade; Heba Constantly; Pernille Hansen; Philippe Halban; Sarah Ferber; Christopher B Newgard; Karl Normington
Topics:
cell lines
,
engineering
,
glucokinase
,
insulin
,
insulinoma
Diabetes June 1997, Vol.46, 958-967. doi:https://doi.org/10.2337/diab.46.6.958
Regulation of Insulin Secretion From Novel Engineered Insulinoma Cell Lines
Hans E Hohmeier; Hector BeltrandelRio; Samuel A Clark; Rosemarie Henkel-Rieger; Karl Normington; Christopher B Newgard
Topics:
cell lines
,
insulinoma
,
regulation of insulin secretion
Diabetes June 1997, Vol.46, 968-977. doi:https://doi.org/10.2337/diab.46.6.968
Proinsulin Conversion in GH3 Cells After Coexpression of Human Proinsulin With the Endoproteases PC2 and/or PC3
Topics:
proinsulin
Diabetes June 1997, Vol.46, 978-982. doi:https://doi.org/10.2337/diab.46.6.978
Skeletal Muscle Triglyceride Levels Are Inversely Related to Insulin Action
Topics:
insulin
,
skeletal muscles
,
triglycerides
Diabetes June 1997, Vol.46, 983-988. doi:https://doi.org/10.2337/diab.46.6.983
Circulating Leptin in Normal Children and During the Dynamic Phase of Juvenile Obesity: Relation to Body Fatness, Energy Metabolism, Caloric Intake, and Sexual Dimorphism
Topics:
child
,
energy intake
,
energy metabolism
,
leptin
,
obesity
Diabetes June 1997, Vol.46, 989-993. doi:https://doi.org/10.2337/diab.46.6.989
Mechanisms of the Kinetic Defect in Insulin Action in Obesity and NIDDM
Topics:
diabetes mellitus, type 2
,
insulin
,
kinetics
,
obesity
Diabetes June 1997, Vol.46, 994-1000. doi:https://doi.org/10.2337/diab.46.6.994
Metabolic Defects in Lean Nondiabetic Offspring of NIDDM Parents: A Cross-Sectional Study
Topics:
diabetes mellitus, type 2
Diabetes June 1997, Vol.46, 1001-1009. doi:https://doi.org/10.2337/diab.46.6.1001
Evidence of Increased Systemic Glucose Production and Gluconeogenesis in an Early Stage of NIDDM
Gabriele Perriello; Simone Pampanelli; Paola Del Sindaco; Carlo Lalli; Marco Ciofetta; Elena Volpi; Fausto Santeusanio; Paolo Brunetti; Geremia B Bolli
Topics:
diabetes mellitus, type 2
,
gluconeogenesis
,
glucose
Diabetes June 1997, Vol.46, 1010-1016. doi:https://doi.org/10.2337/diab.46.6.1010
Regulation of Glycogen Synthase Activity in Cultured Skeletal Muscle Cells From Subjects With Type II Diabetes: Role of Chronic Hyperinsulinemia and Hyperglycemia
Svetlana E Nikoulina; Theodore P Ciaraldi; Leslie Abrams-Carter; Sunder Mudaliar; Kyong Park Soo; Henry R Robert
Topics:
diabetes mellitus, type 2
,
glycogen (starch) synthase
,
hyperglycemia
,
hyperinsulinism
,
skeletal myocytes
Diabetes June 1997, Vol.46, 1017-1024. doi:https://doi.org/10.2337/diab.46.6.1017
Acute Postchallenge Hyperinsulinemia Predicts Weight Gain: A Prospective Study
Ronald J Sigal; Mona El-Hashimy; Blaise C Martin; J Stuart Soeldner; Andrzej S Krolewski; James H Warram
Topics:
hyperinsulinism
,
weight gain
Diabetes June 1997, Vol.46, 1025-1029. doi:https://doi.org/10.2337/diab.46.6.1025
D-Glucose Stimulates Mesangial Cell GLUT1 Expression and Basal and IGF-I–Sensitive Glucose Uptake in Rat Mesangial Cells: Implications for Diabetic Nephropathy
Charles W Heilig; Yanan Liu; Rebecca L England; Svend O Freytag; Jeffery D Gilbert; Kathleen O Heilig; Min Zhu; Luis A Concepcion; Frank C Brosius, II
Topics:
diabetic nephropathy
,
glucose
,
glucose uptake
,
insulin-like growth factor i
,
mesangial cells
Diabetes June 1997, Vol.46, 1030-1039. doi:https://doi.org/10.2337/diab.46.6.1030
Forearm Nitric Oxide Balance, Vascular Relaxation, and Glucose Metabolism in NIDDM Patients
Angelo Avogaro; Francesco Piarulli; Anna Valerio; Marina Miola; Massimo Calveri; Paola Pavan; Paolo Vicini; Claudio Cobelli; Antonio Tiengo; Lorenzo Calò; Stefano Del Prato
Topics:
diabetes mellitus, type 2
,
forearm
,
glucose metabolism
,
nitric oxide
Diabetes June 1997, Vol.46, 1040-1047. doi:https://doi.org/10.2337/diab.46.6.1040
Modulatory Effect of Erythrocytes on the Platelet Reactivity to Collagen in IDDM Patients
Topics:
blood platelets
,
collagen
,
diabetes mellitus, type 1
,
erythrocytes
Diabetes June 1997, Vol.46, 1047-1053. doi:https://doi.org/10.2337/diab.46.6.1047
Vitamin E Decreases the Occurrence of Malformations in the Offspring of Diabetic Rats
Topics:
congenital abnormality
,
rats
,
vitamin e
Diabetes June 1997, Vol.46, 1054-1061. doi:https://doi.org/10.2337/diab.46.6.1054
Genetics of NIDDM in France: Studies With 19 Candidate Genes in Affected Sib Pairs
Nathalie Vionnet; El Habib Hani; Suzanne Lesage; Anne Philippi; Jörg Hager; Mathilde Varret; Markus Stoffel; Yukio Tanizawa; Ken C Chiu; Benjamin Glaser; M Alan Permutt; Philippe Passa; Florence Demenais; Philippe Froguel
Topics:
candidate disease gene
,
diabetes mellitus, type 2
,
genetics
Diabetes June 1997, Vol.46, 1062-1068. doi:https://doi.org/10.2337/diab.46.6.1062
Analysis of Candidate Genes for Susceptibility to Type I Diabetes: A Case-Control and Family-Association Study of Genes on Chromosome 2q31–35
David Owerbach; Francisco J Naya; Ming-Jer Tsai; Susanne V Allander; David R Powell; Kenneth H Gabbay
Topics:
candidate disease gene
,
chromosomes
,
diabetes mellitus, type 1
,
genes
Diabetes June 1997, Vol.46, 1069-1074. doi:https://doi.org/10.2337/diab.46.6.1069
Brief Genetics Report
Polymorphisms in the Interleukin-1 Gene Cluster Do Not Contribute to the Genetic Susceptibility of Diabetic Nephropathy in Caucasian Patients With IDDM
Lise Tarnow; Flemming Pociot; Pernille M Hansen; Peter Rossing; Flemming S Nielsen; Birgitte V Hansen; Hans-Henrik Parving
Topics:
diabetes mellitus, type 1
,
diabetic nephropathy
,
gene clusters
,
genetic predisposition to disease
,
interleukin-1
Diabetes June 1997, Vol.46, 1075-1076. doi:https://doi.org/10.2337/diab.46.6.1075
Rapid Publications
Leptin Receptor of Zucker Fatty Rat Performs Reduced Signal Transduction
Topics:
leptin
,
signal transduction
Diabetes June 1997, Vol.46, 1077-1080. doi:https://doi.org/10.2337/diab.46.6.1077
Novel Mutations and a Mutational Hotspot in the M0DY3 Gene
M Alexandra Glucksmann; Markku Lehto; Olga Tayber; Susan Scotti; Lucy Berkemeier; Jacqueline C Pulido; Ye Wu; Waan-Jeng Nir; Lei Fang; Paul Markel; Kevin D. Munnelly; Jill Goranson; Marju Orho; Brian M Young; Jennifer L Whitacre; Cheryl McMenimen; Michael Wantman; Tlinamija Tuomi; James Warram; Carol M Forsblom; Martin Carlsson; James Rosenzweig; Giulia Kennedy; Geoffrey M Duyk; Andrzej S Krolewski; Leif C Groop; Jeffrey D Thomas
Topics:
genes
,
mutation
,
diabetes mellitus, type 2
,
insulin
,
maturity onset diabetes mellitus in young
Diabetes June 1997, Vol.46, 1081-1086. doi:https://doi.org/10.2337/diab.46.6.1081
Leptin Suppression of Insulin Secretion by the Activation of ATP-Sensitive K+ Channels in Pancreatic β-Cells
Topics:
insulin secretion
,
leptin
,
pancreas
,
psychological suppression
Diabetes June 1997, Vol.46, 1087-1093. doi:https://doi.org/10.2337/diab.46.6.1087
Reviewers list
1996 Reviewers for Diabetes
Diabetes June 1997, Vol.46, 1094-1096. doi:https://doi.org/10.2337/diab.46.6.1094
SI Units Table
Système International (SI) Units Table
Diabetes June 1997, Vol.46, 1097. doi:https://doi.org/10.2337/diab.46.6.1097
Organization Section
Organization Section
Diabetes June 1997, Vol.46, 1098-1099. doi:https://doi.org/10.2337/diab.46.6.1098
