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Volume 47, Issue 11

1 November 1998

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Table of Contents

ISSN 0012-1797

EISSN 1939-327X

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Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.

J J Holst; C F Deacon

Abstract

View articletitled, Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.

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Topics: diabetes mellitus, type 2 , dipeptidyl-peptidase iv

Diabetes November 1998, Vol.47, 1663-1670. doi:https://doi.org/10.2337/diabetes.47.11.1663

Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions.

D H Han; P A Hansen; L A Nolte; J O Holloszy

Abstract

View articletitled, Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions.

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Topics: adenosine , glucose transport , insulin

Diabetes November 1998, Vol.47, 1671-1675. doi:https://doi.org/10.2337/diabetes.47.11.1671

Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.

E Tsiani; E Bogdanovic; A Sorisky; L Nagy; I G Fantus

Abstract

View articletitled, Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.

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Topics: 1-phosphatidylinositol 3-kinase , glucose transport , muscle cells , protein kinase c , protein tyrosine phosphatase

Diabetes November 1998, Vol.47, 1676-1686. doi:https://doi.org/10.2337/diabetes.47.11.1676

Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus.

N A Tritos; D Vicent; J Gillette; D S Ludwig; E S Flier; E Maratos-Flier

Abstract

View articletitled, Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus.

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Topics: appetite depressants , hormones , hypothalamus , melanins , neuropeptide y

Diabetes November 1998, Vol.47, 1687-1692. doi:https://doi.org/10.2337/diabetes.47.11.1687

Interorgan signaling between adipose tissue metabolism and skeletal muscle uncoupling protein homologs: is there a role for circulating free fatty acids?

S Samec; J Seydoux; A G Dulloo

Abstract

View articletitled, Interorgan signaling between adipose tissue metabolism and skeletal muscle uncoupling protein homologs: is there a role for circulating free fatty acids?

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Topics: adipose tissue , metabolism , mitochondrial uncoupling proteins , nonesterified fatty acids , signal transduction

Diabetes November 1998, Vol.47, 1693-1698. doi:https://doi.org/10.2337/diabetes.47.11.1693

Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+.

T Niwa; Y Matsukawa; T Senda; Y Nimura; H Hidaka; I Niki

Abstract

View articletitled, Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+.

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Topics: acetylcholine , calcium ions , granules , inositol , insulin

Diabetes November 1998, Vol.47, 1699-1706. doi:https://doi.org/10.2337/diabetes.47.11.1699

Increased levels of free fatty acids in fasted mice stimulate in vivo beta-cell electrical activity.

J Fernandez; M Valdeolmillos

Abstract

View articletitled, Increased levels of free fatty acids in fasted mice stimulate in vivo beta-cell electrical activity.

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Topics: electrical activity of brain , mice , nonesterified fatty acids , pancreatic beta cell

Diabetes November 1998, Vol.47, 1707-1712. doi:https://doi.org/10.2337/diabetes.47.11.1707

The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.

Y Sato; J C Henquin

Abstract

View articletitled, The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.

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Topics: glucose , regulation of insulin secretion

Diabetes November 1998, Vol.47, 1713-1721. doi:https://doi.org/10.2337/diabetes.47.11.1713

Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.

Y A Tian; G Johnson; S J Ashcroft

Abstract

View articletitled, Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.

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Topics: exocytosis , pancreas , protein kinase c , sulfonylurea compounds

Diabetes November 1998, Vol.47, 1722-1726. doi:https://doi.org/10.2337/diabetes.47.11.1722

Diadenosine polyphosphates in insulin-secreting cells: interaction with specific receptors and degradation.

E J Verspohl; B Johannwille

Abstract

View articletitled, Diadenosine polyphosphates in insulin-secreting cells: interaction with specific receptors and degradation.

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Topics: catabolism , pancreatic beta cell , polyphosphates

Diabetes November 1998, Vol.47, 1727-1734. doi:https://doi.org/10.2337/diabetes.47.11.1727

Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake.

M F Nielsen; R Basu; S Wise; A Caumo; C Cobelli; R A Rizza

Abstract

View articletitled, Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake.

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Topics: diabetes mellitus, type 2 , glucose , psychological suppression

Diabetes November 1998, Vol.47, 1735-1747. doi:https://doi.org/10.2337/diabetes.47.11.1735

Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate.

M R Charlton; K S Nair

Abstract

View articletitled, Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate.

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Topics: basal metabolism , catabolism , diabetes mellitus, type 1 , leucine , metabolism

Diabetes November 1998, Vol.47, 1748-1756. doi:https://doi.org/10.2337/diabetes.47.11.1748

Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance.

J M Fernández-Real; M Broch; W Ricart; R Casamitjana; C Gutierrez; J Vendrell; C Richart

Abstract

View articletitled, Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance.

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Topics: insulin resistance , plasma , receptors, tumor necrosis factor, type ii , obesity

Diabetes November 1998, Vol.47, 1757-1762. doi:https://doi.org/10.2337/diabetes.47.11.1757

Glucose production, utilization, and cycling in response to moderate exercise in obese subjects with type 2 diabetes and mild hyperglycemia.

A Giacca; Y Groenewoud; E Tsui; P McClean; B Zinman

Abstract

View articletitled, Glucose production, utilization, and cycling in response to moderate exercise in obese subjects with type 2 diabetes and mild hyperglycemia.

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Topics: diabetes mellitus, type 2 , glucose , hyperglycemia , obesity

Diabetes November 1998, Vol.47, 1763-1770. doi:https://doi.org/10.2337/diabetes.47.11.1763

Role for heparin-binding growth factors in glucose-induced vascular dysfunction.

C C Stephan; K C Chang; W LeJeune; D Erichsen; R J Bjercke; A Rege; R J Biediger; T P Kogan; T A Brock; J R Williamson; R G Tilton

Abstract

View articletitled, Role for heparin-binding growth factors in glucose-induced vascular dysfunction.

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Topics: glucose , growth factor , heparin

Diabetes November 1998, Vol.47, 1771-1778. doi:https://doi.org/10.2337/diabetes.47.11.1771

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats.

J D Delcroix; G J Michael; J V Priestley; D R Tomlinson; P Fernyhough

Abstract

View articletitled, Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats.

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Topics: ganglia, spinal , gene expression , nerve growth factor 1 , nerve growth factors , rats

Diabetes November 1998, Vol.47, 1779-1785. doi:https://doi.org/10.2337/diabetes.47.11.1779

Microalbuminuria and coronary heart disease in NIDDM: an incidence study.

M B Mattock; D J Barnes; G Viberti; H Keen; D Burt; J M Hughes; A P Fitzgerald; B Sandhu; P G Jackson

Abstract

View articletitled, Microalbuminuria and coronary heart disease in NIDDM: an incidence study.

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Topics: coronary heart disease , diabetes mellitus, type 2 , microalbuminuria

Diabetes November 1998, Vol.47, 1786-1792. doi:https://doi.org/10.2337/diabetes.47.11.1786

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

J T Shaw; P K Lovelock; J B Kesting; J Cardinal; D Duffy; B Wainwright; D P Cameron

Abstract

View articletitled, Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

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Topics: chromosomes, human , diabetes mellitus, type 2 , genes

Diabetes November 1998, Vol.47, 1793-1796. doi:https://doi.org/10.2337/diabetes.47.11.1793

Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group.

L Esposito; N J Hill; L E Pritchard; F Cucca; C Muxworthy; M E Merriman; A Wilson; C Julier; M Delepine; J Tuomilehto; E Tuomilehto-Wolf; C Ionesco-Tirgoviste; L Nistico'; R Buzzetti; P Pozzilli; M Ferrari; E Bosi; F Pociot; J Nerup; S C Bain; J A Todd

View articletitled, Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group.

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Topics: candidate disease gene , chromosomes, human, pair 2 , diabetes mellitus, type 1 , gene clusters , genetic analysis

Diabetes November 1998, Vol.47, 1797-1799. doi:https://doi.org/10.2337/diabetes.47.11.1797

Mitochondrial diabetes: investigation and identification of a novel mutation.

S Lynn; T Wardell; M A Johnson; P F Chinnery; M E Daly; M Walker; D M Turnbull

View articletitled, Mitochondrial diabetes: investigation and identification of a novel mutation.

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Topics: mitochondrial diabetes , mutation

Diabetes November 1998, Vol.47, 1800-1802. doi:https://doi.org/10.2337/diabetes.47.11.1800

Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.

J Cai; S A Phelan; A L Hill; M R Loeken

View articletitled, Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.

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Topics: embryo , gene expression , genes , pregnancy , transcription factor

Diabetes November 1998, Vol.47, 1803-1805. doi:https://doi.org/10.2337/diabetes.47.11.1803

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.

B A Beamer; C J Yen; R E Andersen; D Muller; D Elahi; L J Cheskin; R Andres; J Roth; A R Shuldiner

View articletitled, Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.

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Topics: genes , obesity , peroxisome

Diabetes November 1998, Vol.47, 1806-1808. doi:https://doi.org/10.2337/diabetes.47.11.1806

Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.

J Matsuda; K Hosoda; H Itoh; C Son; K Doi; I Hanaoka; G Inoue; H Nishimura; Y Yoshimasa; Y Yamori; H Odaka; K Nakao

Abstract

View articletitled, Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.

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Topics: adipocytes , genes , rats , thiazolidinedione , uncoupling protein 3

Diabetes November 1998, Vol.47, 1809-1814. doi:https://doi.org/10.2337/diabetes.47.11.1809

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MRI Metrics of Cerebral Endothelial Cell–Derived Exosomes for the Treatment of Cognitive Dysfunction Induced in Aging Rats Subjected to Type 2 Diabetes

Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel

Elevated First-Trimester Neutrophil Count Is Closely Associated With the Development of Maternal Gestational Diabetes Mellitus and Adverse Pregnancy Outcomes

Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis

Screening for Type 1 Diabetes in the General Population: A Status Report and Perspective

Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes.

Removal of adenosine decreases the responsiveness of muscle glucose transport to insulin and contractions.

Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.

Functional interactions between melanin-concentrating hormone, neuropeptide Y, and anorectic neuropeptides in the rat hypothalamus.

Interorgan signaling between adipose tissue metabolism and skeletal muscle uncoupling protein homologs: is there a role for circulating free fatty acids?

Acetylcholine activates intracellular movement of insulin granules in pancreatic beta-cells via inositol trisphosphate-dependent [correction of triphosphate-dependent] mobilization of intracellular Ca2+.

Increased levels of free fatty acids in fasted mice stimulate in vivo beta-cell electrical activity.

The K+-ATP channel-independent pathway of regulation of insulin secretion by glucose: in search of the underlying mechanism.

Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.

Diadenosine polyphosphates in insulin-secreting cells: interaction with specific receptors and degradation.

Normal glucose-induced suppression of glucose production but impaired stimulation of glucose disposal in type 2 diabetes: evidence for a concentration-dependent defect in uptake.

Role of hyperglucagonemia in catabolism associated with type 1 diabetes: effects on leucine metabolism and the resting metabolic rate.

Plasma levels of the soluble fraction of tumor necrosis factor receptor 2 and insulin resistance.

Glucose production, utilization, and cycling in response to moderate exercise in obese subjects with type 2 diabetes and mild hyperglycemia.

Role for heparin-binding growth factors in glucose-induced vascular dysfunction.

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats.

Microalbuminuria and coronary heart disease in NIDDM: an incidence study.

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

Genetic analysis of chromosome 2 in type 1 diabetes: analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. IMDIAB Group.

Mitochondrial diabetes: investigation and identification of a novel mutation.

Identification of Dep-1, a new gene regulated by the transcription factor Pax-3, as a marker for altered embryonic gene expression during diabetic pregnancy.

Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations.

Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.

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