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1 August 1998
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ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Molecular Basis for HLA-DQ Associations With IDDM
Topics:
diabetes mellitus, type 1
,
hla-dq antigens
Diabetes August 1998, Vol.47, 1177-1184. doi:https://doi.org/10.2337/diab.47.8.1177
Original Articles
Metabolism and signal Transduction
Overexpression of Glycogen Phosphorylase Increases GLUT4 Expression and Glucose Transport in Cultured Skeletal Human Muscle
Diabetes August 1998, Vol.47, 1185-1192. doi:https://doi.org/10.2337/diab.47.8.1185
Troglitazone Upregulates LDL Receptor Activity in HepG2 Cells
Topics:
low density lipoprotein receptor
,
troglitazone
Diabetes August 1998, Vol.47, 1193-1198. doi:https://doi.org/10.2337/diab.47.8.1193
Immunology and Transplantation
Prolonged Survival of Rat Islet and Skin Xenografts in Mice Treated with Donor Splenocytes and Anti-CD154 Monoclonal Antibody
Ethel J Gordon; Thomas G Markees; Nancy E Phillips; Randolph J Noelle; Leonard D Shultz; John P Mordes; Aldo A Rossini; Dale L Greiner
Topics:
cd40 ligand
,
donors
,
mice
,
monoclonal antibodies
,
skin
Diabetes August 1998, Vol.47, 1199-1206. doi:https://doi.org/10.2337/diab.47.8.1199
Interleukin-4 Deficiency Does Not Exacerbate Disease in NOD Mice
Topics:
interleukin-4
,
mice, inbred nod
,
symptom aggravating factors
Diabetes August 1998, Vol.47, 1207-1211. doi:https://doi.org/10.2337/diab.47.8.1207
Splenic Macrophages From the NOD Mouse Are Defective in the Ability to Present Antigen
Topics:
antigens
,
mice, inbred nod
,
splenic macrophage
Diabetes August 1998, Vol.47, 1212-1218. doi:https://doi.org/10.2337/diab.47.8.1212
Islet Studies
Lactate Production in Pancreatic Islets
Topics:
endocrine pancreas
,
lactates
Diabetes August 1998, Vol.47, 1219-1223. doi:https://doi.org/10.2337/diab.47.8.1219
In Situ Characterization of Nonmitochondrial Ca2+ Stores in Individual Pancreatic β-Cells
Topics:
pancreas
Diabetes August 1998, Vol.47, 1224-1230. doi:https://doi.org/10.2337/diab.47.8.1224
Mutation P291fsinsC in the Transcription Factor Hepatocyte Nuclear Factor-1α is Dominant Negative
Kazuya Yamagata; Qin Yang; Koji Yamamoto; Hiromi Iwahashi; Jun-ichiro Miyagawa; Kohei Okita; Issei Yoshiuchi; Jun-ichi Miyazaki; Tamio Noguchi; Hiromu Nakajima; Mitsuyoshi Namba; Toshiaki Hanafusa; Yuji Matsuzawa
Topics:
dominant-negative mutation
,
hepatocytes
,
mutation
,
transcription factor
Diabetes August 1998, Vol.47, 1231-1235. doi:https://doi.org/10.2337/diab.47.8.1231
Fibroblast Growth Factor 2 Promotes Pancreatic Epithelial Cell Proliferation Via Functional Fibroblast Growth Factor Receptors During Embryonic Life
Topics:
embryo
,
epithelial cells
,
fibroblast growth factor 2
,
fibroblast growth factor receptors
,
pancreas
Diabetes August 1998, Vol.47, 1236-1242. doi:https://doi.org/10.2337/diab.47.8.1236
Insulin Receptor Signaling in the β-Cell Influences Insulin Gene Expression and Insulin Content: Evidence for Autocrine β-Cell Regulation
Topics:
autocrine
,
gene expression
,
insulin
,
insulin receptor
,
signal transduction
Diabetes August 1998, Vol.47, 1243-1252. doi:https://doi.org/10.2337/diab.47.8.1243
Improved Glucose Tolerance in Zucker Fatty Rats by Oral Administration of the Dipeptidyl Peptidase IV Inhibitor Isoleucine Thiazolidide
Raymond A Pederson; Heather A White; Dagmar Schlenzig; Robert P Pauly; Christopher H S McIntosh; Hans-Ulrich Demuth
Topics:
administration, oral
,
dipeptidyl-peptidase iv inhibitors
,
glucose tolerance
,
isoleucine
,
rats
Diabetes August 1998, Vol.47, 1253-1258. doi:https://doi.org/10.2337/diab.47.8.1253
Glucagon-Like Peptide 1 Improves the Ability of the β-Cell to Sense and Respond to Glucose in Subjects With Impaired Glucose Tolerance
Maria M Byrne; Katja Gliem; Uwe Wank; Rudolf Arnold; Martin Katschinski; Kenneth S Polonsky; Burkhard Goke
Topics:
glucagon-like peptide 1
,
glucose
,
glucose intolerance
Diabetes August 1998, Vol.47, 1259-1265. doi:https://doi.org/10.2337/diab.47.8.1259
Temporal and Quantitative Correlations Between Insulin Secretion and Stably Elevated or Oscillatory Cytoplasmic Ca2+ in Mouse Pancreatic β-Cells
Topics:
cytoplasm
,
insulin secretion
,
mice
,
pancreas
,
glucose
Diabetes August 1998, Vol.47, 1266-1273. doi:https://doi.org/10.2337/diab.47.8.1266
Cloning of the Promoters for the β-Cell ATP-Sensitive K-Channel Subunits Kir6.2 and SUR1
Topics:
abcc8 gene
,
cloning
,
oncogenes
,
potassium channel
,
dna
Diabetes August 1998, Vol.47, 1274-1280. doi:https://doi.org/10.2337/diab.47.8.1274
Pathophysiology
Insulin-Stimulated Akt Kinase Activity Is Reduced in Skeletal Muscle From NIDDM Subjects
Topics:
diabetes mellitus, type 2
,
insulin
,
phosphotransferases
,
proto-oncogene proteins c-akt
,
skeletal muscles
Diabetes August 1998, Vol.47, 1281-1286. doi:https://doi.org/10.2337/diab.47.8.1281
NIDDM Genes in Mice: Deleterious Synergism by Both Parental Genomes Contributes to Diabetogenic Thresholds
Edward H Leiter; Peter C Reifsnyder; Kevin Flurkey; Hans-Joachim Partke; Erika Junger; Lieselotte Herberg
Topics:
diabetes mellitus, type 2
,
genes
,
genome
,
mice
Diabetes August 1998, Vol.47, 1287-1295. doi:https://doi.org/10.2337/diab.47.8.1287
Effect of Physiological Hyperinsulinemia on Blood Flow and Interstitial Glucose Concentration in Human Skeletal Muscle and Adipose Tissue Studied by Microdialysis
Topics:
adipose tissue
,
glucose
,
hyperinsulinism
,
microdialysis
,
skeletal muscles
Diabetes August 1998, Vol.47, 1296-1301. doi:https://doi.org/10.2337/diab.47.8.1296
Gestational Diabetes: Antepartum Characteristics That Predict Postpartum Glucose Intolerance and Type 2 Diabetes in Latino Women
Thomas A Buchanan; Anny Xiang; Siri L Kjos; W Paul Lee; Enrique Trigo; Isabel Nader; E Anne Bergner; Jerry P Palmer; Ruth K Peters
Diabetes August 1998, Vol.47, 1302-1310. doi:https://doi.org/10.2337/diab.47.8.1302
Complications
Matrix Metalloproteinase Expression in Human Retinal Microvascular Cells
Maria B Grant; Sergio Caballero; Roy W Tarnuzzer; Kathryn E Bass; Alexander V Ljubimov; Polyxenie E Spoerri; Richard E Galardy
Topics:
matrix metalloproteinases
Diabetes August 1998, Vol.47, 1311-1317. doi:https://doi.org/10.2337/diab.47.8.1311
Altered Activities of Transcription Factors and Their Related Gene Expression in Cardiac Tissues of Diabetic Rats
Yoshihiko Nishio; Atsunori Kashiwagi; Hideki Taki; Kazuya Shinozaki; Yasuhiro Maeno; Hideto Kojima; Hiroshi Maegawa; Masakazu Haneda; Hideki Hidaka; Hitoshi Yasuda; Kihachiro Horiike; Ryuichi Kikkawa
Topics:
gene expression
,
rats
,
transcription factor
Diabetes August 1998, Vol.47, 1318-1325. doi:https://doi.org/10.2337/diab.47.8.1318
Peroxisome Proliferator-Activated Receptor-γ Agonist, Rosiglitazone, Protects Against Nephropathy and Pancreatic Islet Abnormalities in Zucker Fatty Rats
Robin E Buckingham; Kamal A Al-Barazanji; C D Nigel Toseland; Mark Slaughter; Susan C Connor; Andrew West; Brian Bond; Nicholas C Turner; John C Clapham
Topics:
agonists
,
endocrine pancreas
,
kidney diseases
,
peroxisome
,
rats
Diabetes August 1998, Vol.47, 1326-1334. doi:https://doi.org/10.2337/diab.47.8.1326
Fibronectin Fragments Modulate Human Retinal Capillary Cell Proliferation and Migration
Topics:
blood capillaries
,
cell proliferation
,
fibronectins
Diabetes August 1998, Vol.47, 1335-1340. doi:https://doi.org/10.2337/diab.47.8.1335
Contribution of Growth Hormone and IGF-I to Early Diabetic Nephropathy in Type 1 Diabetes
Topics:
diabetes mellitus, type 1
,
diabetic nephropathy
,
insulin-like growth factor i
,
somatotropin
,
somatropin
Diabetes August 1998, Vol.47, 1341-1346. doi:https://doi.org/10.2337/diab.47.8.1341
Enhanced Responsiveness of Blood Pressure to Sodium Intake and to Angiotensin II Is Associated With Insulin Resistance in IDDM Patients With Mcroalbuminuria
Roberto Trevisan; Daniela Bruttomesso; Monica Vedovato; Stefano Brocco; Alessandro Pianta; Cinzia Mazzon; Carlo Girardi; Elisabetta Jori; Andrea Semplicini; Antonio Tiengo; Stefano Del Prato
Topics:
angiotensin ii
,
blood pressure
,
diabetes mellitus, type 1
,
insulin resistance
,
sodium intake
Diabetes August 1998, Vol.47, 1347-1353. doi:https://doi.org/10.2337/diab.47.8.1347
Brief Genetics Report
Frameshift Mutation, A263fsinsGG, in the Hepatocyte Nuclear Factor-1β Gene Associated With Diabetes and Renal Dysfunction
Hidekazu Nishigori; Shirou Yamada; Tomoko Kohama; Hideaki Tomura; Kimie Sho; Yukio Horikawa; Graeme I Bell; Toshiyuki Takeuchi; Jun Takeda
Topics:
frameshift mutation function
,
genes
,
hepatocytes
,
kidney failure
Diabetes August 1998, Vol.47, 1354-1355. doi:https://doi.org/10.2337/diab.47.8.1354
β-Cell Transcription Factors and Diabetes: Mutations in the Coding Region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) Genes Are Not Associated With Maturity-Onset Diabetes of the Young in Japanese
Hiroto Furuta; Yukio Horikawa; Naoko Iwasaki; Manami Hara; Lori Sussel; Michelle M Le Beau; Elizabeth M Davis; Makiko Ogata; Yasuhiko Iwamoto; Michael S German; Graeme I Bell
Topics:
genes
,
maturity onset diabetes mellitus in young
,
mutation
,
open reading frames
,
transcription factor
Diabetes August 1998, Vol.47, 1356-1358. doi:https://doi.org/10.2337/diab.47.8.1356
The g/a Nucleotide Variant at Position −30 in the β-Cell-Specific Glucokinase Gene Promoter Has No Impact on the β-Cell Function in Danish Caucasians
Topics:
genes
,
glucokinase
,
nucleotides
Diabetes August 1998, Vol.47, 1359-1361. doi:https://doi.org/10.2337/diab.47.8.1359
Multiple Molecular Mechanisms of Insulin Receptor Dysfunction in a Patient With Donohue Syndrome
Jonathan P Whitehead; Maria A Soos; Robert Jackson; Velibor Tasic; Mirjana Kocova; Stephen O'Rahilly
Topics:
donohue syndrome
,
insulin receptor
Diabetes August 1998, Vol.47, 1362-1364. doi:https://doi.org/10.2337/diab.47.8.1362
Rapid Publications
Human Preadipocytes Display a Depot-Specific Susceptibility to Apoptosis
Topics:
apoptosis
,
obesity
,
tumor necrosis factors
,
acridine orange
,
diabetes mellitus, type 2
Diabetes August 1998, Vol.47, 1365-1368. doi:https://doi.org/10.2337/diab.47.8.1365
Evidence for 5′AMP-Activated Protein Kinase Mediation of the Effect of Muscle Contraction on Glucose Transport
Topics:
glucose transport
,
muscle contraction
,
protein kinase
Diabetes August 1998, Vol.47, 1369-1373. doi:https://doi.org/10.2337/diab.47.8.1369
Erratum
Organization Section
Organization Section
Diabetes August 1998, Vol.47, 1375-1376. doi:https://doi.org/10.2337/diab.47.8.1375
Systeme International (SI) units
TABLE 1—Systeme International (SI) units for plasma, serum, or blood concentrations
Topics:
plasma
Diabetes August 1998, Vol.47, 1377. doi:https://doi.org/10.2337/diab.47.8.1377
