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Volume 48, Issue 8

1 August 1999

ISSN 0012-1797

EISSN 1939-327X

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Cow's milk and type 1 diabetes: the real debate is about mucosal immune function.

L C Harrison; M C Honeyman

Abstract

View articletitled, Cow's milk and type 1 diabetes: the real debate is about mucosal immune function.

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Topics: cow's milk , diabetes mellitus, type 1 , immunologic function , mucous membrane

Diabetes August 1999, Vol.48, 1501-1507. doi:https://doi.org/10.2337/diabetes.48.8.1501

Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle.

X Huang; K F Eriksson; A Vaag; M Lehtovirta; M Hansson; E Laurila; T Kanninen; B T Olesen; I Kurucz; L Koranyi; L Groop

Abstract

View articletitled, Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle.

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Topics: gene expression , glucose , insulin , mitochondria , skeletal muscles

Diabetes August 1999, Vol.48, 1508-1514. doi:https://doi.org/10.2337/diabetes.48.8.1508

Visceral fat, insulin sensitivity, and lipids in prepubertal children.

B A Gower; T R Nagy; M I Goran

Abstract

View articletitled, Visceral fat, insulin sensitivity, and lipids in prepubertal children.

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Topics: child , insulin sensitivity , lipids , prepuberty , visceral fat

Diabetes August 1999, Vol.48, 1515-1521. doi:https://doi.org/10.2337/diabetes.48.8.1515

Interleukin-13 prevents autoimmune diabetes in NOD mice.

P Zaccone; J Phillips; I Conget; R Gomis; K Haskins; A Minty; K Bendtzen; A Cooke; F Nicoletti

Abstract

View articletitled, Interleukin-13 prevents autoimmune diabetes in NOD mice.

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Topics: autoimmunity , interleukin-13 , mice, inbred nod

Diabetes August 1999, Vol.48, 1522-1528. doi:https://doi.org/10.2337/diabetes.48.8.1522

Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants.

K Kelemen; M L Crawford; R G Gill; J C Hutton; D Wegmann

Abstract

View articletitled, Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants.

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Topics: immune response , mice, inbred nod , t-lymphocytes

Diabetes August 1999, Vol.48, 1529-1534. doi:https://doi.org/10.2337/diabetes.48.8.1529

Glucose regulation of glutaminolysis and its role in insulin secretion.

Z Y Gao; G Li; H Najafi; B A Wolf; F M Matschinsky

Abstract

View articletitled, Glucose regulation of glutaminolysis and its role in insulin secretion.

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Topics: glucose , insulin secretion

Diabetes August 1999, Vol.48, 1535-1542. doi:https://doi.org/10.2337/diabetes.48.8.1535

Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.

M Komatsu; H Yajima; S Yamada; T Kaneko; Y Sato; K Yamauchi; K Hashizume; T Aizawa

Abstract

View articletitled, Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.

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Topics: calcium ions , endocrine pancreas , fatty acids , glucose , insulin

Diabetes August 1999, Vol.48, 1543-1549. doi:https://doi.org/10.2337/diabetes.48.8.1543

Screening for novel pancreatic genes expressed during embryogenesis.

M Hebrok; S K Kim; D A Melton

Abstract

View articletitled, Screening for novel pancreatic genes expressed during embryogenesis.

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Topics: embryologic development , genes , pancreas , screening

Diabetes August 1999, Vol.48, 1550-1556. doi:https://doi.org/10.2337/diabetes.48.8.1550

Deficiency of phosphofructo-1-kinase/muscle subtype in humans is associated with impairment of insulin secretory oscillations.

M Ristow; H Carlqvist; J Hebinck; M Vorgerd; W Krone; A Pfeiffer; D Müller-Wieland; C G Ostenson

Abstract

View articletitled, Deficiency of phosphofructo-1-kinase/muscle subtype in humans is associated with impairment of insulin secretory oscillations.

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Topics: insulin , phosphotransferases

Diabetes August 1999, Vol.48, 1557-1561. doi:https://doi.org/10.2337/diabetes.48.8.1557

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.

M E Patti; A Virkamäki; E J Landaker; C R Kahn; H Yki-Järvinen

Abstract

View articletitled, Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.

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Topics: glucosamine , hexosamines , insulin , insulin resistance , signal transduction

Diabetes August 1999, Vol.48, 1562-1571. doi:https://doi.org/10.2337/diabetes.48.8.1562

Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon?

J W Eriksson; U Smith; F Waagstein; M Wysocki; P A Jansson

Abstract

View articletitled, Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon?

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Topics: adipose tissue , diabetes mellitus, type 2 , glucose , insulin , insulin resistance

Diabetes August 1999, Vol.48, 1572-1578. doi:https://doi.org/10.2337/diabetes.48.8.1572

Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.

K Aoki; T Saito; S Satoh; K Mukasa; M Kaneshiro; S Kawasaki; A Okamura; H Sekihara

Abstract

View articletitled, Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.

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Topics: dehydroepiandrosterone , fructose , glucose-6-phosphatase , mice , mice, inbred c57bl

Diabetes August 1999, Vol.48, 1579-1585. doi:https://doi.org/10.2337/diabetes.48.8.1579

Regional postprandial fatty acid metabolism in different obesity phenotypes.

Z Guo; D D Hensrud; C M Johnson; M D Jensen

Abstract

View articletitled, Regional postprandial fatty acid metabolism in different obesity phenotypes.

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Topics: fatty acid metabolism , obesity , phenotype , postprandial period

Diabetes August 1999, Vol.48, 1586-1592. doi:https://doi.org/10.2337/diabetes.48.8.1586

Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes.

P Wu; K Inskeep; M M Bowker-Kinley; K M Popov; R A Harris

Abstract

View articletitled, Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes.

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Topics: pyruvate dehydrogenase complex , skeletal muscles , starvation

Diabetes August 1999, Vol.48, 1593-1599. doi:https://doi.org/10.2337/diabetes.48.8.1593

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

G Perseghin; P Scifo; F De Cobelli; E Pagliato; A Battezzati; C Arcelloni; A Vanzulli; G Testolin; G Pozza; A Del Maschio; L Luzi

Abstract

View articletitled, Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

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Topics: insulin resistance , nuclear magnetic resonance , spectrum analysis , triglycerides

Diabetes August 1999, Vol.48, 1600-1606. doi:https://doi.org/10.2337/diabetes.48.8.1600

Metabolic factors contributing to increased resting metabolic rate and decreased insulin-induced thermogenesis during the development of type 2 diabetes.

C Weyer; C Bogardus; R E Pratley

Abstract

View articletitled, Metabolic factors contributing to increased resting metabolic rate and decreased insulin-induced thermogenesis during the development of type 2 diabetes.

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Topics: basal metabolism , diabetes mellitus, type 2 , insulin , thermogenesis

Diabetes August 1999, Vol.48, 1607-1614. doi:https://doi.org/10.2337/diabetes.48.8.1607

Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

H Masuzaki; Y Ogawa; M Aizawa-Abe; K Hosoda; J Suga; K Ebihara; N Satoh; H Iwai; G Inoue; H Nishimura; Y Yoshimasa; K Nakao

Abstract

View articletitled, Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

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Topics: glucose metabolism , insulin sensitivity , leptin , mice, transgenic , mutation

Diabetes August 1999, Vol.48, 1615-1622. doi:https://doi.org/10.2337/diabetes.48.8.1615

Relationship between insulin resistance and nonmodulating hypertension: linkage of metabolic abnormalities and cardiovascular risk.

C Ferri; C Bellini; G Desideri; M Valenti; G De Mattia; A Santucci; N K Hollenberg; G H Williams

Abstract

View articletitled, Relationship between insulin resistance and nonmodulating hypertension: linkage of metabolic abnormalities and cardiovascular risk.

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Topics: heart disease risk factors , hypertension , insulin resistance

Diabetes August 1999, Vol.48, 1623-1630. doi:https://doi.org/10.2337/diabetes.48.8.1623

Plasma phospholipid transfer protein activity is lowered by 24-h insulin and acipimox administration: blunted response to insulin in type 2 diabetic patients.

S C Riemens; A van Tol; W J Sluiter; R P Dullaart

Abstract

View articletitled, Plasma phospholipid transfer protein activity is lowered by 24-h insulin and acipimox administration: blunted response to insulin in type 2 diabetic patients.

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Topics: insulin , phospholipid exchange proteins , plasma

Diabetes August 1999, Vol.48, 1631-1637. doi:https://doi.org/10.2337/diabetes.48.8.1631

IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy.

E Lupia; S J Elliot; O Lenz; F Zheng; M Hattori; G E Striker; L J Striker

Abstract

View articletitled, IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy.

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Topics: catabolism , collagen , diabetic nephropathy , insulin-like growth factor i , mesangial cells

Diabetes August 1999, Vol.48, 1638-1644. doi:https://doi.org/10.2337/diabetes.48.8.1638

Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype.

S P Miller; G R Anand; E J Karschnia; G I Bell; D C LaPorte; A J Lange

Abstract

View articletitled, Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype.

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Topics: glucokinase , maturity onset diabetes mellitus in young , mutation , phenotype

Diabetes August 1999, Vol.48, 1645-1651. doi:https://doi.org/10.2337/diabetes.48.8.1645

Hyperinsulinism caused by paternal-specific inheritance of a recessive mutation in the sulfonylurea-receptor gene.

B Glaser; F Ryan; M Donath; H Landau; C A Stanley; L Baker; D E Barton; P S Thornton

Abstract

View articletitled, Hyperinsulinism caused by paternal-specific inheritance of a recessive mutation in the sulfonylurea-receptor gene.

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Topics: genes , genetic inheritance , hyperinsulinism , mutation , sulfonylurea receptor

Diabetes August 1999, Vol.48, 1652-1657. doi:https://doi.org/10.2337/diabetes.48.8.1652

Association between type 1 diabetes age of onset and HLA among sibling pairs.

A M Valdes; G Thomson; H A Erlich; J A Noble

Abstract

View articletitled, Association between type 1 diabetes age of onset and HLA among sibling pairs.

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Topics: age of onset , diabetes mellitus, type 1 , human leukocyte antigens

Diabetes August 1999, Vol.48, 1658-1661. doi:https://doi.org/10.2337/diabetes.48.8.1658

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice.

H Eldar-Finkelman; S A Schreyer; M M Shinohara; R C LeBoeuf; E G Krebs

Abstract

View articletitled, Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice.

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Topics: glycogen synthase kinase 3 , mice , mice, inbred c57bl , obesity

Diabetes August 1999, Vol.48, 1662-1666. doi:https://doi.org/10.2337/diabetes.48.8.1662

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

E J Kurth-Kraczek; M F Hirshman; L J Goodyear; W W Winder

Abstract

View articletitled, 5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

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Topics: protein kinase , skeletal muscles , translocation (genetics)

Diabetes August 1999, Vol.48, 1667-1671. doi:https://doi.org/10.2337/diabetes.48.8.1667

Cow's milk and type 1 diabetes: the real debate is about mucosal immune function.

Insulin-regulated mitochondrial gene expression is associated with glucose flux in human skeletal muscle.

Visceral fat, insulin sensitivity, and lipids in prepubertal children.

Interleukin-13 prevents autoimmune diabetes in NOD mice.

Cellular immune response to phogrin in the NOD mouse: cloned T-cells cause destruction of islet transplants.

Glucose regulation of glutaminolysis and its role in insulin secretion.

Augmentation of Ca2+-stimulated insulin release by glucose and long-chain fatty acids in rat pancreatic islets: free fatty acids mimic ATP-sensitive K+ channel-independent insulinotropic action of glucose.

Screening for novel pancreatic genes expressed during embryogenesis.

Deficiency of phosphofructo-1-kinase/muscle subtype in humans is associated with impairment of insulin secretory oscillations.

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle.

Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon?

Dehydroepiandrosterone suppresses the elevated hepatic glucose-6-phosphatase and fructose-1,6-bisphosphatase activities in C57BL/Ksj-db/db mice: comparison with troglitazone.

Regional postprandial fatty acid metabolism in different obesity phenotypes.

Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes.

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

Metabolic factors contributing to increased resting metabolic rate and decreased insulin-induced thermogenesis during the development of type 2 diabetes.

Glucose metabolism and insulin sensitivity in transgenic mice overexpressing leptin with lethal yellow agouti mutation: usefulness of leptin for the treatment of obesity-associated diabetes.

Relationship between insulin resistance and nonmodulating hypertension: linkage of metabolic abnormalities and cardiovascular risk.

Plasma phospholipid transfer protein activity is lowered by 24-h insulin and acipimox administration: blunted response to insulin in type 2 diabetic patients.

IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy.

Characterization of glucokinase mutations associated with maturity-onset diabetes of the young type 2 (MODY-2): different glucokinase defects lead to a common phenotype.

Hyperinsulinism caused by paternal-specific inheritance of a recessive mutation in the sulfonylurea-receptor gene.

Association between type 1 diabetes age of onset and HLA among sibling pairs.

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice.

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

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