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Volume 49, Issue 10

1 October 2000

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Table of Contents

ISSN 0012-1797

EISSN 1939-327X

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GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

H Reijonen; T L Daniels; A Lernmark; G T Nepom

Abstract

View articletitled, GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

Topics: autoantibodies , t-lymphocyte epitopes

Diabetes October 2000, Vol.49, 1621-1626. doi:https://doi.org/10.2337/diabetes.49.10.1621

Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

G Delpierre; M H Rider; F Collard; V Stroobant; F Vanstapel; H Santos; E Van Schaftingen

Abstract

View articletitled, Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

Topics: cloning , fructosamine , mammals , phosphotransferases

Diabetes October 2000, Vol.49, 1627-1634. doi:https://doi.org/10.2337/diabetes.49.10.1627

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

R Burcelin; W Dolci; B Thorens

Abstract

View articletitled, Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

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Topics: glucose , hypoglycemia , infusion procedures , mice , sensor

Diabetes October 2000, Vol.49, 1635-1642. doi:https://doi.org/10.2337/diabetes.49.10.1635

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice.

R Burcelin; W Dolci; B Thorens

Abstract

View articletitled, Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice.

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Topics: glucose , mice , sensor

Diabetes October 2000, Vol.49, 1643-1648. doi:https://doi.org/10.2337/diabetes.49.10.1643

5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.

I P Salt; J M Connell; G W Gould

Abstract

View articletitled, 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.

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Topics: adipocytes , aica ribonucleotide , glucose transport , insulin , ribonucleosides

Diabetes October 2000, Vol.49, 1649-1656. doi:https://doi.org/10.2337/diabetes.49.10.1649

Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.

J Paronen; M Knip; E Savilahti; S M Virtanen; J Ilonen; H K Akerblom; O Vaarala

Abstract

View articletitled, Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.

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Topics: cow's milk , diabetes mellitus, type 1 , diet , finnish , genetic risk

Diabetes October 2000, Vol.49, 1657-1665. doi:https://doi.org/10.2337/diabetes.49.10.1657

Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat.

K L Kover; Z Geng; D M Hess; C D Benjamin; W V Moore

Abstract

View articletitled, Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat.

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Topics: cd40 ligand , isogeneic transplantation

Diabetes October 2000, Vol.49, 1666-1670. doi:https://doi.org/10.2337/diabetes.49.10.1666

Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans.

V Gmyr; J Kerr-Conte; S Belaich; B Vandewalle; E Leteurtre; M C Vantyghem; M Lecomte-Houcke; C Proye; J Lefebvre; F Pattou

Abstract

View articletitled, Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans.

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Topics: fibrinogen , insulin , keratins , pancreas , stem cells

Diabetes October 2000, Vol.49, 1671-1680. doi:https://doi.org/10.2337/diabetes.49.10.1671

Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.

M A Hussain; P B Daniel; J F Habener

Abstract

View articletitled, Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.

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Topics: cyclic amp , gene expression , glucagon , insulin , pancreas

Diabetes October 2000, Vol.49, 1681-1690. doi:https://doi.org/10.2337/diabetes.49.10.1681

Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes.

M P Christiansen; P A Linfoot; R A Neese; M K Hellerstein

Abstract

View articletitled, Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes.

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Topics: diabetes mellitus, type 2 , diet , glucose

Diabetes October 2000, Vol.49, 1691-1699. doi:https://doi.org/10.2337/diabetes.49.10.1691

Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

H Sakoda; T Ogihara; M Anai; M Funaki; K Inukai; H Katagiri; Y Fukushima; Y Onishi; H Ono; M Fujishiro; M Kikuchi; Y Oka; T Asano

Abstract

View articletitled, Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

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Topics: adipocytes , dexamethasone , glucose transport , insulin , insulin resistance

Diabetes October 2000, Vol.49, 1700-1708. doi:https://doi.org/10.2337/diabetes.49.10.1700

Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant.

A Tchernof; R D Starling; A Turner; A R Shuldiner; J D Walston; K Silver; E T Poehlman

Abstract

View articletitled, Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant.

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Topics: adrenergic receptor , genes , obesity , postmenopause , visceral fat

Diabetes October 2000, Vol.49, 1709-1713. doi:https://doi.org/10.2337/diabetes.49.10.1709

Glycolaldehyde, a reactive intermediate for advanced glycation end products, plays an important role in the generation of an active ligand for the macrophage scavenger receptor.

R Nagai; K Matsumoto; X Ling; H Suzuki; T Araki; S Horiuchi

Abstract

View articletitled, Glycolaldehyde, a reactive intermediate for advanced glycation end products, plays an important role in the generation of an active ligand for the macrophage scavenger receptor.

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Topics: glycosylation end products, advanced , ligands , macrophages , receptors, scavenger

Diabetes October 2000, Vol.49, 1714-1723. doi:https://doi.org/10.2337/diabetes.49.10.1714

Activity of the glycosylating enzyme, core 2 GlcNAc (beta1,6) transferase, is higher in polymorphonuclear leukocytes from diabetic patients compared with age-matched control subjects: relevance to capillary occlusion in diabetic retinopathy.

R Chibber; B M Ben-Mahmud; D Coppini; E Christ; E M Kohner

Abstract

View articletitled, Activity of the glycosylating enzyme, core 2 GlcNAc (beta1,6) transferase, is higher in polymorphonuclear leukocytes from diabetic patients compared with age-matched control subjects: relevance to capillary occlusion in diabetic retinopathy.

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Topics: blood capillaries , cd29 antigen , diabetic retinopathy , enzymes , neutrophils

Diabetes October 2000, Vol.49, 1724-1730. doi:https://doi.org/10.2337/diabetes.49.10.1724

Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis.

T Ordög; I Takayama; W K Cheung; S M Ward; K M Sanders

Abstract

View articletitled, Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis.

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Topics: diabetic gastroparesis , interstitial cells of cajal , mice

Diabetes October 2000, Vol.49, 1731-1739. doi:https://doi.org/10.2337/diabetes.49.10.1731

Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes.

M Kossila; M Sinkovic; P Kärkkäinen; M O Laukkanen; R Miettinen; J Rissanen; P Kekäläinen; J Kuusisto; S Ylä-Herttuala; M Laakso

Abstract

View articletitled, Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes.

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Topics: 1-phosphatidylinositol 3-kinase , catalytic domain , cloning , diabetes mellitus, type 2 , genes

Diabetes October 2000, Vol.49, 1740-1743. doi:https://doi.org/10.2337/diabetes.49.10.1740

NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

N J Hill; P A Lyons; N Armitage; J A Todd; L S Wicker; L B Peterson

Abstract

View articletitled, NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

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Topics: bcl2 gene , bcl-2 protein , candidate disease gene , caspase-8 , cd28 antigens

Diabetes October 2000, Vol.49, 1744-1747. doi:https://doi.org/10.2337/diabetes.49.10.1744

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GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65.

Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice.

5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes.

Effect of cow's milk exposure and maternal type 1 diabetes on cellular and humoral immunization to dietary insulin in infants at genetic risk for type 1 diabetes. Finnish Trial to Reduce IDDM in the Genetically at Risk Study Group.

Anti-CD154 (CD40L) prevents recurrence of diabetes in islet isografts in the DR-BB rat.

Adult human cytokeratin 19-positive cells reexpress insulin promoter factor 1 in vitro: further evidence for pluripotent pancreatic stem cells in humans.

Glucagon stimulates expression of the inducible cAMP early repressor and suppresses insulin gene expression in pancreatic beta-cells.

Effect of dietary energy restriction on glucose production and substrate utilization in type 2 diabetes.

Dexamethasone-induced insulin resistance in 3T3-L1 adipocytes is due to inhibition of glucose transport rather than insulin signal transduction.

Impaired capacity to lose visceral adipose tissue during weight reduction in obese postmenopausal women with the Trp64Arg beta3-adrenoceptor gene variant.

Glycolaldehyde, a reactive intermediate for advanced glycation end products, plays an important role in the generation of an active ligand for the macrophage scavenger receptor.

Activity of the glycosylating enzyme, core 2 GlcNAc (beta1,6) transferase, is higher in polymorphonuclear leukocytes from diabetic patients compared with age-matched control subjects: relevance to capillary occlusion in diabetic retinopathy.

Remodeling of networks of interstitial cells of Cajal in a murine model of diabetic gastroparesis.

Gene encoding the catalytic subunit p110beta of human phosphatidylinositol 3-kinase: cloning, genomic structure, and screening for variants in patients with type 2 diabetes.

NOD Idd5 locus controls insulitis and diabetes and overlaps the orthologous CTLA4/IDDM12 and NRAMP1 loci in humans.

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