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Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1.
Topics:
glucose
,
glycogen
,
protein phosphatase
Diabetes December 2000, Vol.49, 1967-1977. doi:https://doi.org/10.2337/diabetes.49.12.1967
Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.
Topics:
glucose transport
,
nitric oxide synthase
,
protein kinase
Diabetes December 2000, Vol.49, 1978-1985. doi:https://doi.org/10.2337/diabetes.49.12.1978
Baculovirus-mediated gene transfer into pancreatic islet cells.
Topics:
baculoviruses
,
endocrine pancreas
,
gene transfer techniques
Diabetes December 2000, Vol.49, 1986-1991. doi:https://doi.org/10.2337/diabetes.49.12.1986
Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts.
Topics:
interleukin-1
,
mice, inbred nod
,
rna, messenger
,
tissue transplants
,
transforming growth factor beta
Diabetes December 2000, Vol.49, 1992-1997. doi:https://doi.org/10.2337/diabetes.49.12.1992
Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice.
K Fujihira; M Nagata; H Moriyama; H Yasuda; K Arisawa; M Nakayama; S Maeda; M Kasuga; K Okumura; H Yagita; K Yokono
Topics:
autoimmunity
,
interleukin-12
,
mice, inbred nod
,
neutralization
,
psychological suppression
Diabetes December 2000, Vol.49, 1998-2006. doi:https://doi.org/10.2337/diabetes.49.12.1998
Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice.
Topics:
autoimmunity
,
diabetes mellitus, type 1
,
interferon type ii
,
mice, inbred nod
,
signal transduction
Diabetes December 2000, Vol.49, 2007-2011. doi:https://doi.org/10.2337/diabetes.49.12.2007
Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells.
J S Dillon; G C Yaney; Y Zhou; N Voilley; S Bowen; S Chipkin; C R Bliss; V Schultz; F C Schuit; M Prentki; D J Waxman; B E Corkey
Topics:
dehydroepiandrosterone sulfate
,
gene expression
,
glucose
,
insulin secretion
,
pancreas
Diabetes December 2000, Vol.49, 2012-2020. doi:https://doi.org/10.2337/diabetes.49.12.2012
Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion.
K Yamamoto; J Miyagawa; M Waguri; R Sasada; K Igarashi; M Li; T Nammo; M Moriwaki; A Imagawa; K Yamagata; H Nakajima; M Namba; Y Tochino; T Hanafusa; Y Matsuzawa
Topics:
alloxan
,
betacellulin
,
glucose intolerance
,
mice
,
perfusion
Diabetes December 2000, Vol.49, 2021-2027. doi:https://doi.org/10.2337/diabetes.49.12.2021
Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets.
Topics:
calcium
,
electrical activity of brain
,
endocrine pancreas
,
glucose
,
mice
Diabetes December 2000, Vol.49, 2028-2038. doi:https://doi.org/10.2337/diabetes.49.12.2028
Hedgehog signaling regulation of insulin production by pancreatic beta-cells.
Topics:
erinaceidae
,
insulin
,
pancreas
,
signal transduction
Diabetes December 2000, Vol.49, 2039-2047. doi:https://doi.org/10.2337/diabetes.49.12.2039
Subcellular localization, mobility, and kinetic activity of glucokinase in glucose-responsive insulin-secreting cells.
Topics:
glucokinase
,
glucose
,
kinetics
,
mobility
,
pancreatic beta cell
Diabetes December 2000, Vol.49, 2048-2055. doi:https://doi.org/10.2337/diabetes.49.12.2048
beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes.
Topics:
amyloid
,
diabetes mellitus, type 2
,
glucokinase
,
hyperglycemia
,
mice
Diabetes December 2000, Vol.49, 2056-2062. doi:https://doi.org/10.2337/diabetes.49.12.2056
Mechanism by which metformin reduces glucose production in type 2 diabetes.
R S Hundal; M Krssak; S Dufour; D Laurent; V Lebon; V Chandramouli; S E Inzucchi; W C Schumann; K F Petersen; B R Landau; G I Shulman
Topics:
diabetes mellitus, type 2
,
glucose
,
metformin
Diabetes December 2000, Vol.49, 2063-2069. doi:https://doi.org/10.2337/diabetes.49.12.2063
Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance.
Topics:
fructose
,
glucose intolerance
,
glutamine
,
glycogen
,
hyperlipidemia
Diabetes December 2000, Vol.49, 2070-2078. doi:https://doi.org/10.2337/diabetes.49.12.2070
Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes.
J C Parker; R K McPherson; K M Andrews; C B Levy; J S Dubins; J E Chin; P V Perry; B Hulin; D A Perry; T Inagaki; K A Dekker; K Tachikawa; Y Sugie; J L Treadway
Topics:
antagonists
,
glucagon
,
hepatocytes
Diabetes December 2000, Vol.49, 2079-2086. doi:https://doi.org/10.2337/diabetes.49.12.2079
Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity.
Topics:
adipocytes
,
insulin sensitivity
,
liver
,
troglitazone
Diabetes December 2000, Vol.49, 2087-2093. doi:https://doi.org/10.2337/diabetes.49.12.2087
A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance: evidence for a pathogenic role of relative hyperinsulinemia.
Topics:
diabetes mellitus, type 2
,
fasting
,
hyperinsulinism
,
insulin
,
insulin resistance
Diabetes December 2000, Vol.49, 2094-2101. doi:https://doi.org/10.2337/diabetes.49.12.2094
Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise.
Topics:
fatty acids
,
oxidation
,
plasma
Diabetes December 2000, Vol.49, 2102-2107. doi:https://doi.org/10.2337/diabetes.49.12.2102
Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level.
Diabetes December 2000, Vol.49, 2108-2115. doi:https://doi.org/10.2337/diabetes.49.12.2108
Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response.
Topics:
drug clearance
,
insulin
,
insulin resistance
,
pancreatic beta cell
Diabetes December 2000, Vol.49, 2116-2125. doi:https://doi.org/10.2337/diabetes.49.12.2116
A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes.
Diabetes December 2000, Vol.49, 2126-2134. doi:https://doi.org/10.2337/diabetes.49.12.2126
Prandial glucose effectiveness and fasting gluconeogenesis in insulin-resistant first-degree relatives of patients with type 2 diabetes.
M F Nielsen; B Nyholm; A Caumo; V Chandramouli; W C Schumann; C Cobelli; B R Landau; R A Rizza; O Schmitz
Topics:
diabetes mellitus, type 2
,
fasting
,
gluconeogenesis
,
glucose
,
insulin
Diabetes December 2000, Vol.49, 2135-2141. doi:https://doi.org/10.2337/diabetes.49.12.2135
Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro.
M Lepore; S Pampanelli; C Fanelli; F Porcellati; L Bartocci; A Di Vincenzo; C Cordoni; E Costa; P Brunetti; G B Bolli
Topics:
insulin
,
insulin administration
,
insulin analogs
,
insulin glargine
,
insulin lispro
Diabetes December 2000, Vol.49, 2142-2148. doi:https://doi.org/10.2337/diabetes.49.12.2142
Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls.
Topics:
adipose tissue
,
adolescent
,
agonists
,
girls
,
lipolysis
Diabetes December 2000, Vol.49, 2149-2153. doi:https://doi.org/10.2337/diabetes.49.12.2149
Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat.
Topics:
insulin
,
obesity
,
thiazolidinedione
Diabetes December 2000, Vol.49, 2154-2159. doi:https://doi.org/10.2337/diabetes.49.12.2154
Native and modified LDL activate extracellular signal-regulated kinases in mesangial cells.
Topics:
loudness discomfort level
,
low-density lipoproteins
,
mesangial cells
,
mitogen-activated protein kinases
Diabetes December 2000, Vol.49, 2160-2169. doi:https://doi.org/10.2337/diabetes.49.12.2160
Defective intracellular antioxidant enzyme production in type 1 diabetic patients with nephropathy.
Topics:
antioxidants
,
enzymes
,
kidney diseases
Diabetes December 2000, Vol.49, 2170-2177. doi:https://doi.org/10.2337/diabetes.49.12.2170
APOE polymorphisms and the development of diabetic nephropathy in type 1 diabetes: results of case-control and family-based studies.
Diabetes December 2000, Vol.49, 2190-2195. doi:https://doi.org/10.2337/diabetes.49.12.2190
A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls.
Topics:
genes
,
girls
,
leptin
,
obesity
,
serum leptin measurement
Diabetes December 2000, Vol.49, 2196-2200. doi:https://doi.org/10.2337/diabetes.49.12.2196
Parental transmission of type 2 diabetes: the Framingham Offspring Study.
Diabetes December 2000, Vol.49, 2201-2207. doi:https://doi.org/10.2337/diabetes.49.12.2201
Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships.
D Dabelea; R L Hanson; R S Lindsay; D J Pettitt; G Imperatore; M M Gabir; J Roumain; P H Bennett; W C Knowler
Diabetes December 2000, Vol.49, 2208-2211. doi:https://doi.org/10.2337/diabetes.49.12.2208
Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2.
T Klupa; M T Malecki; M Pezzolesi; L Ji; S Curtis; C D Langefeld; S S Rich; J H Warram; A S Krolewski
Topics:
chromosomes
,
diabetes mellitus, type 2
Diabetes December 2000, Vol.49, 2212-2216. doi:https://doi.org/10.2337/diabetes.49.12.2212
Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B.
Diabetes December 2000, Vol.49, 2217-2221. doi:https://doi.org/10.2337/diabetes.49.12.2217
Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat.
M Collison; A M Glazier; D Graham; J J Morton; M H Dominiczak; T J Aitman; J M Connell; G W Gould; A F Dominiczak
Topics:
cd36 antigens
,
cerebrovascular accident
,
insulin resistance
,
ischemic stroke
,
rats, inbred shr
Diabetes December 2000, Vol.49, 2222-2226. doi:https://doi.org/10.2337/diabetes.49.12.2222