Skip Nav Destination
Issues
Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.
Diabetes February 2000, Vol.49, 143-156. doi:https://doi.org/10.2337/diabetes.49.2.143
Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice.
Topics:
embryonic stem cells
,
mice
,
pancreatic beta cell
,
streptozocin
Diabetes February 2000, Vol.49, 157-162. doi:https://doi.org/10.2337/diabetes.49.2.157
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.
Topics:
pancreas
,
repression
Diabetes February 2000, Vol.49, 163-176. doi:https://doi.org/10.2337/diabetes.49.2.163
Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone.
M S Kim; M Rossi; S Abusnana; D Sunter; D G Morgan; C J Small; C M Edwards; M M Heath; S A Stanley; L J Seal; J R Bhatti; D M Smith; M A Ghatei; S R Bloom
Diabetes February 2000, Vol.49, 177-182. doi:https://doi.org/10.2337/diabetes.49.2.177
The transferrin receptor defines two distinct contraction-responsive GLUT4 vesicle populations in skeletal muscle.
Topics:
skeletal muscles
,
transferrin receptors
,
vesicle
Diabetes February 2000, Vol.49, 183-189. doi:https://doi.org/10.2337/diabetes.49.2.183
Insulin enhances the bradykinin response in L8 rat skeletal myoblasts.
Topics:
bradykinin
,
insulin
,
myoblasts
Diabetes February 2000, Vol.49, 190-194. doi:https://doi.org/10.2337/diabetes.49.2.190
Study of the regulatory properties of glucokinase by site-directed mutagenesis: conversion of glucokinase to an enzyme with high affinity for glucose.
Topics:
affinity
,
enzymes
,
glucokinase
,
glucose
,
mutagenesis, site-directed
Diabetes February 2000, Vol.49, 195-201. doi:https://doi.org/10.2337/diabetes.49.2.195
Maturation of the humoral autoimmune response to epitopes of GAD in preclinical childhood type 1 diabetes.
Topics:
autoimmunity
,
child
,
diabetes mellitus, type 1
,
epitopes
,
generalized anxiety disorder
Diabetes February 2000, Vol.49, 202-208. doi:https://doi.org/10.2337/diabetes.49.2.202
Inhibitory effect of IGF-I on type 2 nitric oxide synthase expression in Ins-1 cells and protection against activation-dependent apoptosis: involvement of phosphatidylinositol 3-kinase.
Topics:
1-phosphatidylinositol 3-kinase
,
apoptosis
,
insulin-like growth factor i
,
nitric oxide synthase
Diabetes February 2000, Vol.49, 209-217. doi:https://doi.org/10.2337/diabetes.49.2.209
Modulation of humoral islet autoimmunity by pancreas allotransplantation influences allograft outcome in patients with type 1 diabetes.
Topics:
allografting
,
autoimmunity
,
diabetes mellitus, type 1
,
pancreas
,
transplantation, homologous
Diabetes February 2000, Vol.49, 218-224. doi:https://doi.org/10.2337/diabetes.49.2.218
Early pattern of differentiation in the human pancreas.
Diabetes February 2000, Vol.49, 225-232. doi:https://doi.org/10.2337/diabetes.49.2.225
Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin.
Topics:
bodily secretions
,
integrins
,
pancreatic beta cell
Diabetes February 2000, Vol.49, 233-243. doi:https://doi.org/10.2337/diabetes.49.2.233
Effects of streptozotocin-induced diabetes and insulin treatment on the hypothalamic melanocortin system and muscle uncoupling protein 3 expression in rats.
Topics:
hypothalamus
,
insulin
,
rats
,
streptozocin
,
uncoupling protein 3
Diabetes February 2000, Vol.49, 244-252. doi:https://doi.org/10.2337/diabetes.49.2.244
Beta-blockade, but not normoglycemia or hyperinsulinemia, markedly diminishes stress-induced hyperglycemia in diabetic dogs.
Topics:
dog, domestic
,
hyperglycemia
,
hyperinsulinism
,
stress
Diabetes February 2000, Vol.49, 253-262. doi:https://doi.org/10.2337/diabetes.49.2.253
Potential role of glycogen synthase kinase-3 in skeletal muscle insulin resistance of type 2 diabetes.
Topics:
diabetes mellitus, type 2
,
glycogen synthase kinase 3
,
insulin resistance
,
skeletal muscles
Diabetes February 2000, Vol.49, 263-271. doi:https://doi.org/10.2337/diabetes.49.2.263
Effects of type 2 diabetes on the ability of insulin and glucose to regulate splanchnic and muscle glucose metabolism: evidence for a defect in hepatic glucokinase activity.
Topics:
diabetes mellitus, type 2
,
glucokinase
,
glucose
,
glucose metabolism
,
insulin
Diabetes February 2000, Vol.49, 272-283. doi:https://doi.org/10.2337/diabetes.49.2.272
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.
A Krook; M Björnholm; D Galuska; X J Jiang; R Fahlman; M G Myers, Jr; H Wallberg-Henriksson; J R Zierath
Topics:
glucose transport
,
signal transduction
,
skeletal muscles
,
insulin
,
insulin receptor
Diabetes February 2000, Vol.49, 284-292. doi:https://doi.org/10.2337/diabetes.49.2.284
Leptin induces direct vasodilation through distinct endothelial mechanisms.
Topics:
endothelium
,
leptin
,
vasodilation
Diabetes February 2000, Vol.49, 293-297. doi:https://doi.org/10.2337/diabetes.49.2.293
Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity.
Topics:
genes
,
glycogen
,
insulin sensitivity
,
polymorphism
,
protein phosphatase
Diabetes February 2000, Vol.49, 298-301. doi:https://doi.org/10.2337/diabetes.49.2.298
Beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the hepatocyte nuclear factor-3beta gene (HNF3B) in Japanese patients with maturity-onset diabetes of the young.
Topics:
genes
,
hepatocytes
,
maturity onset diabetes mellitus in young
,
mutation
,
pancreatic beta cell
Diabetes February 2000, Vol.49, 302-305. doi:https://doi.org/10.2337/diabetes.49.2.302
Genetic variation in the hepatocyte nuclear factor-3beta gene (HNF3B) does not contribute to maturity-onset diabetes of the young in French Caucasians.
A Abderrahmani; J C Chèvre; S Otabe; M Chikri; E H Hani; M Vaxillaire; Y Hinokio; Y Horikawa; G I Bell; P Froguel
Topics:
genes
,
genetics
,
hepatocytes
,
maturity onset diabetes mellitus in young
Diabetes February 2000, Vol.49, 306-308. doi:https://doi.org/10.2337/diabetes.49.2.306