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Volume 49, Issue 5
1 May 2000
Diabetes Cover Image for Volume 49, Issue 5
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ISSN 0012-1797
EISSN 1939-327X
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Fuel selection in human skeletal muscle in insulin resistance: a reexamination.
D E Kelley; L J Mandarino
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Diabetes May 2000, Vol.49, 677-683. doi:https://doi.org/10.2337/diabetes.49.5.677
Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.
R R Shankar; Y Wu; H Q Shen; J S Zhu; A D Baron
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Diabetes May 2000, Vol.49, 684-687. doi:https://doi.org/10.2337/diabetes.49.5.684
Secretion of tumor necrosis factor-alpha shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue.
P Löfgren; V van Harmelen; S Reynisdottir; E Näslund; M Rydén; S Rössner; P Arner
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Diabetes May 2000, Vol.49, 688-692. doi:https://doi.org/10.2337/diabetes.49.5.688
Localization of glucokinase gene expression in the rat brain.
R M Lynch; L S Tompkins; H L Brooks; A A Dunn-Meynell; B E Levin
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Diabetes May 2000, Vol.49, 693-700. doi:https://doi.org/10.2337/diabetes.49.5.693
Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans.
M Roden; H Stingl; V Chandramouli; W C Schumann; A Hofer; B R Landau; P Nowotny; W Waldhäusl; G I Shulman
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Diabetes May 2000, Vol.49, 701-707. doi:https://doi.org/10.2337/diabetes.49.5.701
Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets.
D V Serreze; E W Ottendorfer; T M Ellis; C J Gauntt; M A Atkinson
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Diabetes May 2000, Vol.49, 708-711. doi:https://doi.org/10.2337/diabetes.49.5.708
Cerulenin, an inhibitor of protein acylation, selectively attenuates nutrient stimulation of insulin release: a study in rat pancreatic islets.
H Yajima; M Komatsu; S Yamada; S G Straub; T Kaneko; Y Sato; K Yamauchi; K Hashizume; G W Sharp; T Aizawa
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Diabetes May 2000, Vol.49, 712-717. doi:https://doi.org/10.2337/diabetes.49.5.712
Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.
S Farfari; V Schulz; B Corkey; M Prentki
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Diabetes May 2000, Vol.49, 718-726. doi:https://doi.org/10.2337/diabetes.49.5.718
Cx36 preferentially connects beta-cells within pancreatic islets.
V Serre-Beinier; S Le Gurun; N Belluardo; A Trovato-Salinaro; A Charollais; J A Haefliger; D F Condorelli; P Meda
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Diabetes May 2000, Vol.49, 727-734. doi:https://doi.org/10.2337/diabetes.49.5.727
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells.
G Patanè; S Piro; A M Rabuazzo; M Anello; R Vigneri; F Purrello
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Diabetes May 2000, Vol.49, 735-740. doi:https://doi.org/10.2337/diabetes.49.5.735
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.
D A Stoffers; T J Kieffer; M A Hussain; D J Drucker; S Bonner-Weir; J F Habener; J M Egan
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Diabetes May 2000, Vol.49, 741-748. doi:https://doi.org/10.2337/diabetes.49.5.741
Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients.
L Ryysy; A M Häkkinen; T Goto; S Vehkavaara; J Westerbacka; J Halavaara; H Yki-Järvinen
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Diabetes May 2000, Vol.49, 749-758. doi:https://doi.org/10.2337/diabetes.49.5.749
A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice.
Y Fukui; S Masui; S Osada; K Umesono; K Motojima
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Diabetes May 2000, Vol.49, 759-767. doi:https://doi.org/10.2337/diabetes.49.5.759
Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment.
A D Baron; M Tarshoby; G Hook; E N Lazaridis; J Cronin; A Johnson; H O Steinberg
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Diabetes May 2000, Vol.49, 768-774. doi:https://doi.org/10.2337/diabetes.49.5.768
Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding.
M J Holness; A Kraus; R A Harris; M C Sugden
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Diabetes May 2000, Vol.49, 775-781. doi:https://doi.org/10.2337/diabetes.49.5.775
Response of pancreatic beta-cells to improved insulin sensitivity in women at high risk for type 2 diabetes.
T A Buchanan; A H Xiang; R K Peters; S L Kjos; K Berkowitz; A Marroquin; J Goico; C Ochoa; S P Azen
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Diabetes May 2000, Vol.49, 782-788. doi:https://doi.org/10.2337/diabetes.49.5.782
IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp.
P V Carroll; E R Christ; A M Umpleby; I Gowrie; N Jackson; S B Bowes; R Hovorka; P Croos; P H Sönksen; D L Russell-Jones
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Diabetes May 2000, Vol.49, 789-796. doi:https://doi.org/10.2337/diabetes.49.5.789
Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects.
J Bolinder; D A Kerckhoffs; E Moberg; E Hagström-Toft; P Arner
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Diabetes May 2000, Vol.49, 797-802. doi:https://doi.org/10.2337/diabetes.49.5.797
Delayed insulin transport across endothelium in insulin-resistant JCR:LA-cp rats.
T C Wascher; G Wölkart; J C Russell; F Brunner
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Diabetes May 2000, Vol.49, 803-809. doi:https://doi.org/10.2337/diabetes.49.5.803
Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase.
A T Cheung; J Wang; D Ree; J K Kolls; M Bryer-Ash
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Diabetes May 2000, Vol.49, 810-819. doi:https://doi.org/10.2337/diabetes.49.5.810
Presumed apoptosis and reduced arcuate nucleus neuropeptide Y and pro-opiomelanocortin mRNA in non-coma hypoglycemia.
N C Tkacs; A A Dunn-Meynell; B E Levin
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Diabetes May 2000, Vol.49, 820-826. doi:https://doi.org/10.2337/diabetes.49.5.820
Mechanism of troglitazone action in type 2 diabetes.
K F Petersen; M Krssak; S Inzucchi; G W Cline; S Dufour; G I Shulman
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Diabetes May 2000, Vol.49, 827-831. doi:https://doi.org/10.2337/diabetes.49.5.827
Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.
D Q Shih; H M Dansky; M Fleisher; G Assmann; S S Fajans; M Stoffel
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Diabetes May 2000, Vol.49, 832-837. doi:https://doi.org/10.2337/diabetes.49.5.832
Differential brain responses to satiation in obese and lean men.
J F Gautier; K Chen; A D Salbe; D Bandy; R E Pratley; M Heiman; E Ravussin; E M Reiman; P A Tataranni
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Diabetes May 2000, Vol.49, 838-846. doi:https://doi.org/10.2337/diabetes.49.5.838
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats.
Y B Kim; O D Peroni; T F Franke; B B Kahn
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Diabetes May 2000, Vol.49, 847-856. doi:https://doi.org/10.2337/diabetes.49.5.847
Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion.
S O'Byrne; P Forte; L J Roberts, 2nd; J D Morrow; A Johnston; E Anggård; R D Leslie; N Benjamin
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Diabetes May 2000, Vol.49, 857-862. doi:https://doi.org/10.2337/diabetes.49.5.857
Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells.
H J Goldberg; J Scholey; I G Fantus
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Diabetes May 2000, Vol.49, 863-871. doi:https://doi.org/10.2337/diabetes.49.5.863
The CART gene and human obesity: mutational analysis and population genetics.
B G Challis; G S Yeo; I S Farooqi; J Luan; S Aminian; D J Halsall; J M Keogh; N J Wareham; S O'Rahilly
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Diabetes May 2000, Vol.49, 872-875. doi:https://doi.org/10.2337/diabetes.49.5.872
NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.
L Hansen; J N Jensen; S Urioste; H V Petersen; F Pociot; H Eiberg; O P Kristiansen; T Hansen; P Serup; J Nerup; O Pedersen
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Diabetes May 2000, Vol.49, 876-878. doi:https://doi.org/10.2337/diabetes.49.5.876
Système International (SI) Units Table
Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
713-P: Is There a Correct Time to Measure Fasting Blood Sugar in Persons with Type 2 Diabetes Melitus?
From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus
34-OR: The Effect of Combined Activin A and Myostatin Blockade on Body Composition—A Phase 1 Trial
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