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Fuel selection in human skeletal muscle in insulin resistance: a reexamination.
Topics:
insulin resistance
,
skeletal muscles
Diabetes May 2000, Vol.49, 677-683. doi:https://doi.org/10.2337/diabetes.49.5.677
Mice with gene disruption of both endothelial and neuronal nitric oxide synthase exhibit insulin resistance.
Topics:
endothelium
,
genes
,
insulin resistance
,
mice
,
nitric oxide synthase
Diabetes May 2000, Vol.49, 684-687. doi:https://doi.org/10.2337/diabetes.49.5.684
Secretion of tumor necrosis factor-alpha shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue.
Topics:
adipose tissue
,
bodily secretions
,
glucose transport
,
insulin
,
tumor necrosis factor-alpha
Diabetes May 2000, Vol.49, 688-692. doi:https://doi.org/10.2337/diabetes.49.5.688
Localization of glucokinase gene expression in the rat brain.
Topics:
brain
,
gene expression
,
glucokinase
Diabetes May 2000, Vol.49, 693-700. doi:https://doi.org/10.2337/diabetes.49.5.693
Effects of free fatty acid elevation on postabsorptive endogenous glucose production and gluconeogenesis in humans.
M Roden; H Stingl; V Chandramouli; W C Schumann; A Hofer; B R Landau; P Nowotny; W Waldhäusl; G I Shulman
Topics:
gluconeogenesis
,
glucose
,
nonesterified fatty acids
Diabetes May 2000, Vol.49, 701-707. doi:https://doi.org/10.2337/diabetes.49.5.701
Cerulenin, an inhibitor of protein acylation, selectively attenuates nutrient stimulation of insulin release: a study in rat pancreatic islets.
H Yajima; M Komatsu; S Yamada; S G Straub; T Kaneko; Y Sato; K Yamauchi; K Hashizume; G W Sharp; T Aizawa
Topics:
acylation
,
cerulenin
,
endocrine pancreas
,
insulin
,
nutrients
Diabetes May 2000, Vol.49, 712-717. doi:https://doi.org/10.2337/diabetes.49.5.712
Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.
Topics:
citrates
,
glucose
,
insulin secretion
,
pancreas
,
pyruvates
Diabetes May 2000, Vol.49, 718-726. doi:https://doi.org/10.2337/diabetes.49.5.718
Cx36 preferentially connects beta-cells within pancreatic islets.
V Serre-Beinier; S Le Gurun; N Belluardo; A Trovato-Salinaro; A Charollais; J A Haefliger; D F Condorelli; P Meda
Topics:
endocrine pancreas
Diabetes May 2000, Vol.49, 727-734. doi:https://doi.org/10.2337/diabetes.49.5.727
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cells.
Topics:
glucose
,
insulin secretion
,
metformin
,
nonesterified fatty acids
,
pancreas
Diabetes May 2000, Vol.49, 735-740. doi:https://doi.org/10.2337/diabetes.49.5.735
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.
Topics:
agonists
,
glucagon-like peptide 1
,
homeodomain proteins
,
mice
,
pancreas
Diabetes May 2000, Vol.49, 741-748. doi:https://doi.org/10.2337/diabetes.49.5.741
A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice.
Topics:
antidiabetics
,
mice, obese
,
mitochondrial uncoupling proteins
,
peroxisome proliferator-activated receptors
,
thiazolidinedione
Diabetes May 2000, Vol.49, 759-767. doi:https://doi.org/10.2337/diabetes.49.5.759
Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment.
Topics:
blood capillaries
,
glucose uptake
,
insulin sensitivity
,
perfusion
,
skeletal muscles
Diabetes May 2000, Vol.49, 768-774. doi:https://doi.org/10.2337/diabetes.49.5.768
Targeted upregulation of pyruvate dehydrogenase kinase (PDK)-4 in slow-twitch skeletal muscle underlies the stable modification of the regulatory characteristics of PDK induced by high-fat feeding.
Topics:
pyruvate dehydrogenase (acetyl-transferring) kinase
,
skeletal muscles
,
up-regulation (physiology)
Diabetes May 2000, Vol.49, 775-781. doi:https://doi.org/10.2337/diabetes.49.5.775
Response of pancreatic beta-cells to improved insulin sensitivity in women at high risk for type 2 diabetes.
Topics:
diabetes mellitus, type 2
,
insulin sensitivity
,
pancreas
Diabetes May 2000, Vol.49, 782-788. doi:https://doi.org/10.2337/diabetes.49.5.782
IGF-I treatment in adults with type 1 diabetes: effects on glucose and protein metabolism in the fasting state and during a hyperinsulinemic-euglycemic amino acid clamp.
P V Carroll; E R Christ; A M Umpleby; I Gowrie; N Jackson; S B Bowes; R Hovorka; P Croos; P H Sönksen; D L Russell-Jones
Topics:
amino acids
,
diabetes mellitus, type 1
,
fasting
,
glucose
,
insulin-like growth factor i
Diabetes May 2000, Vol.49, 789-796. doi:https://doi.org/10.2337/diabetes.49.5.789
Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects.
Topics:
adipose tissue
,
glycerol
,
obesity
,
skeletal muscles
Diabetes May 2000, Vol.49, 797-802. doi:https://doi.org/10.2337/diabetes.49.5.797
Delayed insulin transport across endothelium in insulin-resistant JCR:LA-cp rats.
Topics:
endothelium
,
insulin
,
rats
Diabetes May 2000, Vol.49, 803-809. doi:https://doi.org/10.2337/diabetes.49.5.803
Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase.
Topics:
antigens
,
focal adhesions
,
insulin resistance
,
leukocytes
,
obesity
Diabetes May 2000, Vol.49, 810-819. doi:https://doi.org/10.2337/diabetes.49.5.810
Presumed apoptosis and reduced arcuate nucleus neuropeptide Y and pro-opiomelanocortin mRNA in non-coma hypoglycemia.
Topics:
apoptosis
,
coma
,
hypoglycemia
,
neuropeptide y
,
nucleus infundibularis hypothalami
Diabetes May 2000, Vol.49, 820-826. doi:https://doi.org/10.2337/diabetes.49.5.820
Mechanism of troglitazone action in type 2 diabetes.
Topics:
diabetes mellitus, type 2
,
troglitazone
Diabetes May 2000, Vol.49, 827-831. doi:https://doi.org/10.2337/diabetes.49.5.827
Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels.
Topics:
apolipoproteins
,
genotype
,
haploinsufficiency
,
lipoproteins
,
phenotype
Diabetes May 2000, Vol.49, 832-837. doi:https://doi.org/10.2337/diabetes.49.5.832
Differential brain responses to satiation in obese and lean men.
J F Gautier; K Chen; A D Salbe; D Bandy; R E Pratley; M Heiman; E Ravussin; E M Reiman; P A Tataranni
Diabetes May 2000, Vol.49, 838-846. doi:https://doi.org/10.2337/diabetes.49.5.838
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats.
Topics:
akt1 gene
,
insulin
,
obesity
,
protein isoforms
,
rats, zucker
Diabetes May 2000, Vol.49, 847-856. doi:https://doi.org/10.2337/diabetes.49.5.847
Nitric oxide synthesis and isoprostane production in subjects with type 1 diabetes and normal urinary albumin excretion.
Topics:
albumins
,
diabetes mellitus, type 1
,
excretory function
,
isoprostanes
,
nitric oxide
Diabetes May 2000, Vol.49, 857-862. doi:https://doi.org/10.2337/diabetes.49.5.857
Glucosamine activates the plasminogen activator inhibitor 1 gene promoter through Sp1 DNA binding sites in glomerular mesangial cells.
Topics:
binding sites
,
dna
,
genes
,
glucosamine
,
kidney glomerulus
Diabetes May 2000, Vol.49, 863-871. doi:https://doi.org/10.2337/diabetes.49.5.863
The CART gene and human obesity: mutational analysis and population genetics.
B G Challis; G S Yeo; I S Farooqi; J Luan; S Aminian; D J Halsall; J M Keogh; N J Wareham; S O'Rahilly
Topics:
genes
,
genetics, population
,
mutation analysis
,
obesity
Diabetes May 2000, Vol.49, 872-875. doi:https://doi.org/10.2337/diabetes.49.5.872
NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.
L Hansen; J N Jensen; S Urioste; H V Petersen; F Pociot; H Eiberg; O P Kristiansen; T Hansen; P Serup; J Nerup; O Pedersen
Topics:
alleles
,
child
,
danish study
,
diabetes mellitus, type 1
,
diabetes mellitus, type 2
Diabetes May 2000, Vol.49, 876-878. doi:https://doi.org/10.2337/diabetes.49.5.876
