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Volume 49, Issue 9

1 September 2000

ISSN 0012-1797

EISSN 1939-327X

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The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient?

M L Caramori; P Fioretto; M Mauer

Abstract

View articletitled, The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient?

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Topics: albumins , diabetic nephropathy , excretory function

Diabetes September 2000, Vol.49, 1399-1408. doi:https://doi.org/10.2337/diabetes.49.9.1399

Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution.

O Larsson; C J Barker; P O Berggren

Abstract

View articletitled, Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution.

Topics: katp channels , phosphatidylinositols

Diabetes September 2000, Vol.49, 1409-1412. doi:https://doi.org/10.2337/diabetes.49.9.1409

ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.

E Markworth; C Schwanstecher; M Schwanstecher

Abstract

View articletitled, ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.

Topics: katp channels , pancreas , pancreatic beta cell

Diabetes September 2000, Vol.49, 1413-1418. doi:https://doi.org/10.2337/diabetes.49.9.1413

Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite.

N Bergans; W Stalmans; S Goldmann; F Vanstapel

Abstract

View articletitled, Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite.

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Topics: dihydropyridine , glycogen phosphorylase , glycogenolysis , liver , metabolites

Diabetes September 2000, Vol.49, 1419-1426. doi:https://doi.org/10.2337/diabetes.49.9.1419

Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.

S M Furler; G J Cooney; B D Hegarty; M Y Lim-Fraser; E W Kraegen; N D Oakes

Abstract

View articletitled, Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.

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Topics: nonesterified fatty acids , rats

Diabetes September 2000, Vol.49, 1427-1433. doi:https://doi.org/10.2337/diabetes.49.9.1427

Evidence that carotid bodies play an important role in glucoregulation in vivo.

Y Koyama; R H Coker; E E Stone; D B Lacy; K Jabbour; P E Williams; D H Wasserman

Abstract

View articletitled, Evidence that carotid bodies play an important role in glucoregulation in vivo.

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Topics: carotid body , glucose , hypoglycemic agents , insulin

Diabetes September 2000, Vol.49, 1434-1442. doi:https://doi.org/10.2337/diabetes.49.9.1434

Identification of leptin-induced transcripts in the mouse hypothalamus.

D W White; J Zhou; A Stricker-Krongrad; P Ge; J P Morgenstern; M Dembski; L A Tartaglia

Abstract

View articletitled, Identification of leptin-induced transcripts in the mouse hypothalamus.

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Topics: hypothalamus , leptin , mice

Diabetes September 2000, Vol.49, 1443-1450. doi:https://doi.org/10.2337/diabetes.49.9.1443

Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice.

S N Zykova; T G Jenssen; M Berdal; R Olsen; R Myklebust; R Seljelid

Abstract

View articletitled, Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice.

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Topics: bodily secretions , cytokine , macrophages , mice , nitric oxide

Diabetes September 2000, Vol.49, 1451-1458. doi:https://doi.org/10.2337/diabetes.49.9.1451

Prevention of encephalomyocarditis virus-induced diabetes by live recombinant Mycobacterium bovis bacillus Calmette-Guérin in susceptible mice.

B K Choi; S H Cho; G H Bai; S J Kim; B H Hyun; Y K Choe; Y S Bae

Abstract

View articletitled, Prevention of encephalomyocarditis virus-induced diabetes by live recombinant Mycobacterium bovis bacillus Calmette-Guérin in susceptible mice.

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Topics: bacillus , mice , mycobacterium bovis , viruses

Diabetes September 2000, Vol.49, 1459-1467. doi:https://doi.org/10.2337/diabetes.49.9.1459

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

A Ammendrup; A Maillard; K Nielsen; N Aabenhus Andersen; P Serup; O Dragsbaek Madsen; T Mandrup-Poulsen; C Bonny

Abstract

View articletitled, The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

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Topics: apoptosis , interleukin-1 , pancreas , phosphotransferases

Diabetes September 2000, Vol.49, 1468-1476. doi:https://doi.org/10.2337/diabetes.49.9.1468

The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.

C B Verchere; D A D'Alessio; R L Prigeon; R L Hull; S E Kahn

Abstract

View articletitled, The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.

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Topics: bodily secretions , drug administration routes , endocrine pancreas , iapp gene , newborn

Diabetes September 2000, Vol.49, 1477-1484. doi:https://doi.org/10.2337/diabetes.49.9.1477

Glucose uptake, utilization, and signaling in GLUT2-null islets.

M T Guillam; P Dupraz; B Thorens

Abstract

View articletitled, Glucose uptake, utilization, and signaling in GLUT2-null islets.

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Topics: glucose uptake , signal transduction , glucose , glucokinase , insulin

Diabetes September 2000, Vol.49, 1485-1491. doi:https://doi.org/10.2337/diabetes.49.9.1485

Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

J Tang; J L Neidigh; R C Cooksey; D A McClain

Abstract

View articletitled, Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

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Topics: hexosamines , hyperinsulinism , insulin resistance , mice, transgenic

Diabetes September 2000, Vol.49, 1492-1499. doi:https://doi.org/10.2337/diabetes.49.9.1492

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

S Barg; J Galvanovskis; S O Göpel; P Rorsman; L Eliasson

Abstract

View articletitled, Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

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Topics: electrical activity of brain , exocytosis , glucagon , mice , pancreatic alpha cell

Diabetes September 2000, Vol.49, 1500-1510. doi:https://doi.org/10.2337/diabetes.49.9.1500

Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).

D M Porterfield; R F Corkey; R H Sanger; K Tornheim; P J Smith; B E Corkey

Abstract

View articletitled, Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).

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Topics: oxygen consumption , pancreas , calcium ions , glucose

Diabetes September 2000, Vol.49, 1511-1516. doi:https://doi.org/10.2337/diabetes.49.9.1511

Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter.

H I Kim; J W Kim; S H Kim; J Y Cha; K S Kim; Y H Ahn

Abstract

View articletitled, Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter.

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Topics: response elements , peroxisome proliferator-activated receptors , troglitazone , alitretinoin , electrophoretic mobility shift assay

Diabetes September 2000, Vol.49, 1517-1524. doi:https://doi.org/10.2337/diabetes.49.9.1517

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs.

K J Kaiyala; R L Prigeon; S E Kahn; S C Woods; M W Schwartz

Abstract

View articletitled, Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs.

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Topics: brain , diet, high-fat , dog, domestic , insulin , obesity

Diabetes September 2000, Vol.49, 1525-1533. doi:https://doi.org/10.2337/diabetes.49.9.1525

Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.

N Tsuboyama-Kasaoka; M Takahashi; K Tanemura; H J Kim; T Tange; H Okuyama; M Kasai; S Ikemoto; O Ezaki

Abstract

View articletitled, Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.

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Topics: adipose tissue , apoptosis , linoleic acid , lipodystrophy , mice

Diabetes September 2000, Vol.49, 1534-1542. doi:https://doi.org/10.2337/diabetes.49.9.1534

Effect of hypoglycemia on amino acid and protein metabolism in healthy humans.

A Battezzati; S Benedini; A Fattorini; L Piceni Sereni; L Luzi

Abstract

View articletitled, Effect of hypoglycemia on amino acid and protein metabolism in healthy humans.

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Topics: amino acids , hypoglycemia , protein metabolism

Diabetes September 2000, Vol.49, 1543-1551. doi:https://doi.org/10.2337/diabetes.49.9.1543

Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.

L A Scrocchi; M E Hill; J Saleh; B Perkins; D J Drucker

Abstract

View articletitled, Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.

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Topics: glucagon , glucagon-like peptide 1 , leptin , mice , peptides

Diabetes September 2000, Vol.49, 1552-1560. doi:https://doi.org/10.2337/diabetes.49.9.1552

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

P Quehenberger; A Bierhaus; P Fasching; C Muellner; M Klevesath; M Hong; G Stier; M Sattler; E Schleicher; W Speiser; P P Nawroth

Abstract

View articletitled, Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

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Topics: endothelial cells , endothelin-1

Diabetes September 2000, Vol.49, 1561-1570. doi:https://doi.org/10.2337/diabetes.49.9.1561

Coronary calcium in adults with type 1 diabetes: a stronger correlate of clinical coronary artery disease in men than in women.

J C Olson; D Edmundowicz; D J Becker; L H Kuller; T J Orchard

Abstract

View articletitled, Coronary calcium in adults with type 1 diabetes: a stronger correlate of clinical coronary artery disease in men than in women.

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Topics: coronary arteriosclerosis , coronary artery calcium , diabetes mellitus, type 1

Diabetes September 2000, Vol.49, 1571-1578. doi:https://doi.org/10.2337/diabetes.49.9.1571

Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage.

T M Osicka; C A Houlihan; J G Chan; G Jerums; W D Comper

Abstract

View articletitled, Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage.

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Topics: albumins , albuminuria , catabolism , diabetes mellitus, type 1 , kidney

Diabetes September 2000, Vol.49, 1579-1584. doi:https://doi.org/10.2337/diabetes.49.9.1579

Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.

J A Miller; K Thai; J W Scholey

Abstract

View articletitled, Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.

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Topics: diabetes mellitus, type 1 , genes , hyperglycemia , polymorphism , receptor, angiotensin, type 1

Diabetes September 2000, Vol.49, 1585-1589. doi:https://doi.org/10.2337/diabetes.49.9.1585

Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity.

L Plum; R Kluge; K Giesen; J Altmüller; J R Ortlepp; H G Joost

Abstract

View articletitled, Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity.

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Topics: chromosomes, human, pair 4 , hyperglycemia , mice , obesity

Diabetes September 2000, Vol.49, 1590-1596. doi:https://doi.org/10.2337/diabetes.49.9.1590

Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history.

H Shimomura; T Sanke; T Hanabusa; K Tsunoda; H Furuta; K Nanjo

Abstract

View articletitled, Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history.

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Topics: genes , mutation, nonsense , diabetes mellitus, type 2 , amino acids , insulin

Diabetes September 2000, Vol.49, 1597-1600. doi:https://doi.org/10.2337/diabetes.49.9.1597

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

H F Gu; P Almgren; E Lindholm; L Frittitta; A Pizzuti; V Trischitta; L C Groop

Abstract

View articletitled, Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

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Topics: genes , glycoproteins , hyperglycemia , insulin

Diabetes September 2000, Vol.49, 1601-1603. doi:https://doi.org/10.2337/diabetes.49.9.1601

Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans.

J Hebinck; C Hardt; L Schöls; M Vorgerd; L Briedigkeit; C R Kahn; M Ristow

Abstract

View articletitled, Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans.

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Topics: genes , heterozygote , insulin resistance

Diabetes September 2000, Vol.49, 1604-1607. doi:https://doi.org/10.2337/diabetes.49.9.1604

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

S K Rasmussen; S A Urhammer; A Pizzuti; S M Echwald; C T Ekstrøm; L Hansen; T Hansen; K Borch-Johnsen; L Frittitta; V Trischitta; O Pedersen

Abstract

View articletitled, The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

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Topics: diabetes mellitus, type 2 , genes , insulin resistance

Diabetes September 2000, Vol.49, 1608-1611. doi:https://doi.org/10.2337/diabetes.49.9.1608

Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.

T Siegmund; N Armitage; L S Wicker; L B Peterson; J A Todd; P A Lyons

Abstract

View articletitled, Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.

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Topics: antigens, cd30 , diabetes mellitus, type 1 , genes , mice , mice, inbred nod

Diabetes September 2000, Vol.49, 1612-1616. doi:https://doi.org/10.2337/diabetes.49.9.1612

The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient?

Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution.

ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.

Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite.

Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.

Evidence that carotid bodies play an important role in glucoregulation in vivo.

Identification of leptin-induced transcripts in the mouse hypothalamus.

Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice.

Prevention of encephalomyocarditis virus-induced diabetes by live recombinant Mycobacterium bovis bacillus Calmette-Guérin in susceptible mice.

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.

Glucose uptake, utilization, and signaling in GLUT2-null islets.

Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).

Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter.

Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs.

Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.

Effect of hypoglycemia on amino acid and protein metabolism in healthy humans.

Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.

Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.

Coronary calcium in adults with type 1 diabetes: a stronger correlate of clinical coronary artery disease in men than in women.

Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage.

Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.

Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity.

Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history.

Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.

Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans.

The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.

Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.

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