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The need for early predictors of diabetic nephropathy risk: is albumin excretion rate sufficient?
Topics:
albumins
,
diabetic nephropathy
,
excretory function
Diabetes September 2000, Vol.49, 1399-1408. doi:https://doi.org/10.2337/diabetes.49.9.1399
Phosphatidylinositol 4,5-bisphosphate and ATP-sensitive potassium channel regulation: a word of caution.
Topics:
katp channels
,
phosphatidylinositols
Diabetes September 2000, Vol.49, 1409-1412. doi:https://doi.org/10.2337/diabetes.49.9.1409
ATP4- mediates closure of pancreatic beta-cell ATP-sensitive potassium channels by interaction with 1 of 4 identical sites.
Topics:
katp channels
,
pancreas
,
pancreatic beta cell
Diabetes September 2000, Vol.49, 1413-1418. doi:https://doi.org/10.2337/diabetes.49.9.1413
Molecular mode of inhibition of glycogenolysis in rat liver by the dihydropyridine derivative, BAY R3401: inhibition and inactivation of glycogen phosphorylase by an activated metabolite.
Topics:
dihydropyridine
,
glycogen phosphorylase
,
glycogenolysis
,
liver
,
metabolites
Diabetes September 2000, Vol.49, 1419-1426. doi:https://doi.org/10.2337/diabetes.49.9.1419
Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.
Topics:
nonesterified fatty acids
,
rats
Diabetes September 2000, Vol.49, 1427-1433. doi:https://doi.org/10.2337/diabetes.49.9.1427
Evidence that carotid bodies play an important role in glucoregulation in vivo.
Topics:
carotid body
,
glucose
,
hypoglycemic agents
,
insulin
Diabetes September 2000, Vol.49, 1434-1442. doi:https://doi.org/10.2337/diabetes.49.9.1434
Identification of leptin-induced transcripts in the mouse hypothalamus.
Topics:
hypothalamus
,
leptin
,
mice
Diabetes September 2000, Vol.49, 1443-1450. doi:https://doi.org/10.2337/diabetes.49.9.1443
Altered cytokine and nitric oxide secretion in vitro by macrophages from diabetic type II-like db/db mice.
Topics:
bodily secretions
,
cytokine
,
macrophages
,
mice
,
nitric oxide
Diabetes September 2000, Vol.49, 1451-1458. doi:https://doi.org/10.2337/diabetes.49.9.1451
Prevention of encephalomyocarditis virus-induced diabetes by live recombinant Mycobacterium bovis bacillus Calmette-Guérin in susceptible mice.
Topics:
bacillus
,
mice
,
mycobacterium bovis
,
viruses
Diabetes September 2000, Vol.49, 1459-1467. doi:https://doi.org/10.2337/diabetes.49.9.1459
The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.
A Ammendrup; A Maillard; K Nielsen; N Aabenhus Andersen; P Serup; O Dragsbaek Madsen; T Mandrup-Poulsen; C Bonny
Topics:
apoptosis
,
interleukin-1
,
pancreas
,
phosphotransferases
Diabetes September 2000, Vol.49, 1468-1476. doi:https://doi.org/10.2337/diabetes.49.9.1468
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
Topics:
bodily secretions
,
drug administration routes
,
endocrine pancreas
,
iapp gene
,
newborn
Diabetes September 2000, Vol.49, 1477-1484. doi:https://doi.org/10.2337/diabetes.49.9.1477
Glucose uptake, utilization, and signaling in GLUT2-null islets.
Topics:
glucose uptake
,
signal transduction
,
glucose
,
glucokinase
,
insulin
Diabetes September 2000, Vol.49, 1485-1491. doi:https://doi.org/10.2337/diabetes.49.9.1485
Transgenic mice with increased hexosamine flux specifically targeted to beta-cells exhibit hyperinsulinemia and peripheral insulin resistance.
Topics:
hexosamines
,
hyperinsulinism
,
insulin resistance
,
mice, transgenic
Diabetes September 2000, Vol.49, 1492-1499. doi:https://doi.org/10.2337/diabetes.49.9.1492
Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.
Topics:
electrical activity of brain
,
exocytosis
,
glucagon
,
mice
,
pancreatic alpha cell
Diabetes September 2000, Vol.49, 1500-1510. doi:https://doi.org/10.2337/diabetes.49.9.1500
Oxygen consumption oscillates in single clonal pancreatic beta-cells (HIT).
Topics:
oxygen consumption
,
pancreas
,
calcium ions
,
glucose
Diabetes September 2000, Vol.49, 1511-1516. doi:https://doi.org/10.2337/diabetes.49.9.1511
Identification and functional characterization of the peroxisomal proliferator response element in rat GLUT2 promoter.
Topics:
response elements
,
peroxisome proliferator-activated receptors
,
troglitazone
,
alitretinoin
,
electrophoretic mobility shift assay
Diabetes September 2000, Vol.49, 1517-1524. doi:https://doi.org/10.2337/diabetes.49.9.1517
Obesity induced by a high-fat diet is associated with reduced brain insulin transport in dogs.
Topics:
brain
,
diet, high-fat
,
dog, domestic
,
insulin
,
obesity
Diabetes September 2000, Vol.49, 1525-1533. doi:https://doi.org/10.2337/diabetes.49.9.1525
Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice.
N Tsuboyama-Kasaoka; M Takahashi; K Tanemura; H J Kim; T Tange; H Okuyama; M Kasai; S Ikemoto; O Ezaki
Topics:
adipose tissue
,
apoptosis
,
linoleic acid
,
lipodystrophy
,
mice
Diabetes September 2000, Vol.49, 1534-1542. doi:https://doi.org/10.2337/diabetes.49.9.1534
Effect of hypoglycemia on amino acid and protein metabolism in healthy humans.
Topics:
amino acids
,
hypoglycemia
,
protein metabolism
Diabetes September 2000, Vol.49, 1543-1551. doi:https://doi.org/10.2337/diabetes.49.9.1543
Elimination of glucagon-like peptide 1R signaling does not modify weight gain and islet adaptation in mice with combined disruption of leptin and GLP-1 action.
Topics:
glucagon
,
glucagon-like peptide 1
,
leptin
,
mice
,
peptides
Diabetes September 2000, Vol.49, 1552-1560. doi:https://doi.org/10.2337/diabetes.49.9.1552
Endothelin 1 transcription is controlled by nuclear factor-kappaB in AGE-stimulated cultured endothelial cells.
P Quehenberger; A Bierhaus; P Fasching; C Muellner; M Klevesath; M Hong; G Stier; M Sattler; E Schleicher; W Speiser; P P Nawroth
Topics:
endothelial cells
,
endothelin-1
Diabetes September 2000, Vol.49, 1561-1570. doi:https://doi.org/10.2337/diabetes.49.9.1561
Coronary calcium in adults with type 1 diabetes: a stronger correlate of clinical coronary artery disease in men than in women.
Diabetes September 2000, Vol.49, 1571-1578. doi:https://doi.org/10.2337/diabetes.49.9.1571
Albuminuria in patients with type 1 diabetes is directly linked to changes in the lysosome-mediated degradation of albumin during renal passage.
Topics:
albumins
,
albuminuria
,
catabolism
,
diabetes mellitus, type 1
,
kidney
Diabetes September 2000, Vol.49, 1579-1584. doi:https://doi.org/10.2337/diabetes.49.9.1579
Angiotensin II type 1 receptor gene polymorphism and the response to hyperglycemia in early type 1 diabetes.
Topics:
diabetes mellitus, type 1
,
genes
,
hyperglycemia
,
polymorphism
,
receptor, angiotensin, type 1
Diabetes September 2000, Vol.49, 1585-1589. doi:https://doi.org/10.2337/diabetes.49.9.1585
Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity.
Topics:
chromosomes, human, pair 4
,
hyperglycemia
,
mice
,
obesity
Diabetes September 2000, Vol.49, 1590-1596. doi:https://doi.org/10.2337/diabetes.49.9.1590
Nonsense mutation of islet-1 gene (Q310X) found in a type 2 diabetic patient with a strong family history.
Topics:
genes
,
mutation, nonsense
,
diabetes mellitus, type 2
,
amino acids
,
insulin
Diabetes September 2000, Vol.49, 1597-1600. doi:https://doi.org/10.2337/diabetes.49.9.1597
Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis.
Topics:
genes
,
glycoproteins
,
hyperglycemia
,
insulin
Diabetes September 2000, Vol.49, 1601-1603. doi:https://doi.org/10.2337/diabetes.49.9.1601
Heterozygous expansion of the GAA tract of the X25/frataxin gene is associated with insulin resistance in humans.
Topics:
genes
,
heterozygote
,
insulin resistance
Diabetes September 2000, Vol.49, 1604-1607. doi:https://doi.org/10.2337/diabetes.49.9.1604
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.
S K Rasmussen; S A Urhammer; A Pizzuti; S M Echwald; C T Ekstrøm; L Hansen; T Hansen; K Borch-Johnsen; L Frittitta; V Trischitta; O Pedersen
Topics:
diabetes mellitus, type 2
,
genes
,
insulin resistance
Diabetes September 2000, Vol.49, 1608-1611. doi:https://doi.org/10.2337/diabetes.49.9.1608
Analysis of the mouse CD30 gene: a candidate for the NOD mouse type 1 diabetes locus Idd9.2.
Topics:
antigens, cd30
,
diabetes mellitus, type 1
,
genes
,
mice
,
mice, inbred nod
Diabetes September 2000, Vol.49, 1612-1616. doi:https://doi.org/10.2337/diabetes.49.9.1612
