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Issues
Perspectives in Diabetes
Glucose Sensing in Pancreatic β-Cells: A Model for the Study of Other Glucose-Regulated Cells in Gut, Pancreas, and Hypothalamus
Diabetes January 2001, Vol.50, 1-11. doi:https://doi.org/10.2337/diabetes.50.1.1
Chronic Treatment With 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside Increases Insulin-Stimulated Glucose Uptake and GLUT4 Translocation in Rat Skeletal Muscles in a Fiber Type—Specific Manner
Esben S. Buhl; Niels Jessen; Ole Schmitz; Steen B. Pedersen; Oluf Pedersen; Geoffrey D. Holman; Sten Lund
Diabetes January 2001, Vol.50, 12-17. doi:https://doi.org/10.2337/diabetes.50.1.12
Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization
Diabetes January 2001, Vol.50, 18-23. doi:https://doi.org/10.2337/diabetes.50.1.18
Evidence That Insulin is Imprinted in the Human Yolk Sac
Gudrun E. Moore; Sayeda N. Abu-Amero; Gill Bell; Emma L. Wakeling; Amanda Kingsnorth; Philip Stanier; Eric Jauniaux; Simon T. Bennett
Diabetes January 2001, Vol.50, 199-203. doi:https://doi.org/10.2337/diabetes.50.1.199
Type 2 Diabetes Locus on 12q15: Further Mapping and Mutation Screening of Two Candidate Genes
Diabetes January 2001, Vol.50, 204-208. doi:https://doi.org/10.2337/diabetes.50.1.204
Metabolism and Signal Transduction
Serine/Threonine Phosphorylation of IRS-1 Triggers Its Degradation: Possible Regulation by Tyrosine Phosphorylation
Diabetes January 2001, Vol.50, 24-31. doi:https://doi.org/10.2337/diabetes.50.1.24
Physiological Differences in Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) Phosphorylation in IGFBP-1 Transgenic Mice
Diabetes January 2001, Vol.50, 32-38. doi:https://doi.org/10.2337/diabetes.50.1.32
Immunology and Transplantation
Variable Effects of Transgenic c-Maf on Autoimmune Diabetes
Mary E. Pauza; Andrea Nguyen; Tom Wolfe; I-Cheng Ho; Laurie H. Glimcher; Matthias von Herrath; David Lo
Diabetes January 2001, Vol.50, 39-46. doi:https://doi.org/10.2337/diabetes.50.1.39
Prevention of Diabetes for up to 13 Years by Autoislet Transplantation After Pancreatectomy for Chronic Pancreatitis
Diabetes January 2001, Vol.50, 47-50. doi:https://doi.org/10.2337/diabetes.50.1.47
Islet Studies
Amplitude Modulation of Pulsatile Insulin Secretion by Intrapancreatic Ganglion Neurons
Diabetes January 2001, Vol.50, 51-55. doi:https://doi.org/10.2337/diabetes.50.1.51
Glucagon-Like Peptide 1 Stimulates Lipolysis in Clonal Pancreatic β-Cells (HIT)
Gordon C. Yaney; Vildan N. Civelek; Ann-Marie Richard; Joseph S. Dillon; Jude T. Deeney; James A. Hamilton; Helen M. Korchak; Keith Tornheim; Barbara E. Corkey; Aubrey E. Boyd, III
Diabetes January 2001, Vol.50, 56-62. doi:https://doi.org/10.2337/diabetes.50.1.56
A Genetic Defect in β-Cell Gene Expression Segregates Independently From the fa Locus in the ZDF Rat
Diabetes January 2001, Vol.50, 63-68. doi:https://doi.org/10.2337/diabetes.50.1.63
Distinct Effects of Saturated and Monounsaturated Fatty Acids on β-Cell Turnover and Function
Diabetes January 2001, Vol.50, 69-76. doi:https://doi.org/10.2337/diabetes.50.1.69
Cell-Permeable Peptide Inhibitors of JNK: Novel Blockers of β-Cell Death
Diabetes January 2001, Vol.50, 77-82. doi:https://doi.org/10.2337/diabetes.50.1.77
Pathophysiology
Decreased In Situ Insulin Receptor Dephosphorylation in Hyperglycemia-Induced Insulin Resistance in Rat Adipocytes
Diabetes January 2001, Vol.50, 83-90. doi:https://doi.org/10.2337/diabetes.50.1.83
Identification of an Interactive Effect of β3- and α2b-Adrenoceptor Gene Polymorphisms on Fat Mass in Caucasian Women
Isabelle J. Dionne; Amy N. Turner; André Tchernof; Toni I. Pollin; Dionyssia Avrithi; Daniel Gray; Alan R. Shuldiner; Eric T. Poehlman
Diabetes January 2001, Vol.50, 91-95. doi:https://doi.org/10.2337/diabetes.50.1.91
Hypoglycemia Activates Orexin Neurons and Selectively Increases Hypothalamic Orexin-B Levels: Responses Inhibited by Feeding and Possibly Mediated by the Nucleus of the Solitary Tract
Xue J. Cai; Martyn L. Evans; Carolyn A. Lister; Ron A. Leslie; Jonathan R. S. Arch; Shelagh Wilson; Gareth Williams
Diabetes January 2001, Vol.50, 105-112. doi:https://doi.org/10.2337/diabetes.50.1.105
Mechanism of Amelioration of Insulin Resistance by β3-Adrenoceptor Agonist AJ-9677 in the KK-Ay/Ta Diabetic Obese Mouse Model
Hiroshi Kato; Mayumi Ohue; Kaori Kato; Akinori Nomura; Kaoru Toyosawa; Yasuji Furutani; Satoshi Kimura; Takashi Kadowaki
Diabetes January 2001, Vol.50, 113-122. doi:https://doi.org/10.2337/diabetes.50.1.113
Prolonged Inhibition of Muscle Carnitine Palmitoyltransferase-1 Promotes Intramyocellular Lipid Accumulation and Insulin Resistance in Rats
Robert L. Dobbins; Lidia S. Szczepaniak; Brandon Bentley; Victoria Esser; Jeffrey Myhill; J. Denis McGarry
Diabetes January 2001, Vol.50, 123-130. doi:https://doi.org/10.2337/diabetes.50.1.123
Exercise-Stimulated Glucose Turnover in the Rat Is Impaired by Glucosamine Infusion
Diabetes January 2001, Vol.50, 139-142. doi:https://doi.org/10.2337/diabetes.50.1.139
Expression and Role of Bcl-2 in Rat Blastocysts Exposed to High D-Glucose
Serge Pampfer; Sabine Cordi; Ivo Vanderheyden; Patrick Van Der Smissen; Pierre J. Courtoy; Anne Van Cauwenberge; Henri Alexandre; Isabelle Donnay; René De Hertogh
Diabetes January 2001, Vol.50, 143-149. doi:https://doi.org/10.2337/diabetes.50.1.143
Oral Glucose Tolerance Test Minimal Model Indexes of β-Cell Function and Insulin Sensitivity
Diabetes January 2001, Vol.50, 150-158. doi:https://doi.org/10.2337/diabetes.50.1.150
Complications
Obesity and Body Fat Distribution Induce Endothelial Dysfunction by Oxidative Stress: Protective Effect of Vitamin C
Francesco Perticone; Roberto Ceravolo; Mafalda Candigliota; Giorgio Ventura; Saverio Iacopino; Flora Sinopoli; Pier L. Mattioli
Diabetes January 2001, Vol.50, 159-165. doi:https://doi.org/10.2337/diabetes.50.1.159
Reduced Vasorelaxant Effect of Carbon Monoxide in Diabetes and the Underlying Mechanisms
Diabetes January 2001, Vol.50, 166-174. doi:https://doi.org/10.2337/diabetes.50.1.166
IGF-I mRNA and Signaling in the Diabetic Retina
Diabetes January 2001, Vol.50, 175-183. doi:https://doi.org/10.2337/diabetes.50.1.175
Genetics
Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases
Tony R. Merriman; Heather J. Cordell; Iain A. Eaves; Patrick A. Danoy; Francesca Coraddu; Rachael Barber; Francesco Cucca; Simon Broadley; Stephen Sawcer; Alastair Compston; Paul Wordsworth; Jane Shatford; Steve Laval; Johan Jirholt; Rikard Holmdahl; Argyrios N. Theofilopoulos; Dwight H. Kono; Jaakko Tuomilehto; Eva Tuomilehto-Wolf; Raffaella Buzzetti; Maria Giovanna Marrosu; Dag E. Undlien; Kjersti S. Rønningen; C. Ionesco-Tirgoviste; Julian P. Shield; Fleming Pociot; Jorn Nerup; Chaim O. Jacob; Constantin Polychronakos; Steve C. Bain; John A. Todd
Diabetes January 2001, Vol.50, 184-194. doi:https://doi.org/10.2337/diabetes.50.1.184