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Issues
1 October 2001
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set?
Diabetes October 2001, Vol.50, 2181-2191. doi:https://doi.org/10.2337/diabetes.50.10.2181
Rapid Publications
Insulin Activates ATP-Sensitive K+ Channels in Pancreatic β-Cells Through a Phosphatidylinositol 3-Kinase–Dependent Pathway
Diabetes October 2001, Vol.50, 2192-2198. doi:https://doi.org/10.2337/diabetes.50.10.2192
Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator–Activated Receptor-γ Action in Humans
David B. Savage; Ciaran P. Sewter; Ellen S. Klenk; David G. Segal; Antonio Vidal-Puig; Robert V. Considine; Stephen O’Rahilly
Diabetes October 2001, Vol.50, 2199-2202. doi:https://doi.org/10.2337/diabetes.50.10.2199
Metabolism and Signal Transduction
The Effect of Insulin on In Vivo Cerebral Glucose Concentrations and Rates of Glucose Transport/Metabolism in Humans
Diabetes October 2001, Vol.50, 2203-2209. doi:https://doi.org/10.2337/diabetes.50.10.2203
Immunology and Transplantation
Inhibition of Cytokine-Induced NF-κB Activation by Adenovirus-Mediated Expression of a NF-κB Super-Repressor Prevents β-Cell Apoptosis
Harry Heimberg; Yves Heremans; Christian Jobin; Ruth Leemans; Alessandra K. Cardozo; Martine Darville; Décio L. Eizirik
Diabetes October 2001, Vol.50, 2219-2224. doi:https://doi.org/10.2337/diabetes.50.10.2219
Islet Studies
The Expression of Hormone-Sensitive Lipase in Clonal β-Cells and Rat Islets Is Induced by Long-Term Exposure to High Glucose
Diabetes October 2001, Vol.50, 2225-2230. doi:https://doi.org/10.2337/diabetes.50.10.2225
Noninvasive In Vivo Measurement of β-Cell Mass in Mouse Model of Diabetes
Diabetes October 2001, Vol.50, 2231-2236. doi:https://doi.org/10.2337/diabetes.50.10.2231
Protein Kinase Cζ Activation Mediates Glucagon-Like Peptide-1–Induced Pancreatic β-Cell Proliferation
Diabetes October 2001, Vol.50, 2237-2243. doi:https://doi.org/10.2337/diabetes.50.10.2237
Phosphorylation-Dependent Nucleocytoplasmic Shuttling of Pancreatic Duodenal Homeobox-1
Diabetes October 2001, Vol.50, 2244-2252. doi:https://doi.org/10.2337/diabetes.50.10.2244
Structural Basis for the Interference Between Nicorandil and Sulfonylurea Action
Diabetes October 2001, Vol.50, 2253-2259. doi:https://doi.org/10.2337/diabetes.50.10.2253
Inducible and Reversible β-Cell Autoimmunity and Hyperplasia in Transgenic Mice Expressing a Conditional Oncogene
Diabetes October 2001, Vol.50, 2260-2267. doi:https://doi.org/10.2337/diabetes.50.10.2260
Pathophysiology
Effects of Leptin Deficiency and Short-Term Repletion on Hepatic Gene Expression in Genetically Obese Mice
Diabetes October 2001, Vol.50, 2268-2278. doi:https://doi.org/10.2337/diabetes.50.10.2268
Intrauterine Growth Retardation Leads to the Development of Type 2 Diabetes in the Rat
Diabetes October 2001, Vol.50, 2279-2286. doi:https://doi.org/10.2337/diabetes.50.10.2279
Phenotypic Correction of Diabetic Mice by Adenovirus-Mediated Glucokinase Expression
Urvi J. Desai; Eric D. Slosberg; Brian R. Boettcher; Shari L. Caplan; Barbara Fanelli; Zouhair Stephan; Vicky J. Gunther; Michael Kaleko; Sheila Connelly
Diabetes October 2001, Vol.50, 2287-2295. doi:https://doi.org/10.2337/diabetes.50.10.2287
Troglitazone Not Only Increases GLUT4 but Also Induces Its Translocation in Rat Adipocytes
Mitsuyo Shintani; Haruo Nishimura; Shin Yonemitsu; Yoshihiro Ogawa; Tatsuya Hayashi; Kiminori Hosoda; Gen Inoue; Kazuwa Nakao
Diabetes October 2001, Vol.50, 2296-2300. doi:https://doi.org/10.2337/diabetes.50.10.2296
Pharmacological Antilipolysis Restores Insulin Sensitivity During Growth Hormone Exposure
Diabetes October 2001, Vol.50, 2301-2308. doi:https://doi.org/10.2337/diabetes.50.10.2301
Direct Thiazolidinedione Action on Isolated Rat Skeletal Muscle Fuel Handling Is Independent of Peroxisome Proliferator–Activated Receptor-γ−Mediated Changes in Gene Expression
Barbara Brunmair; Florian Gras; Susanne Neschen; Michael Roden; Ludwig Wagner; Werner Waldhäusl; Clemens Fürnsinn
Diabetes October 2001, Vol.50, 2309-2315. doi:https://doi.org/10.2337/diabetes.50.10.2309
Thiazolidinedione Treatment Prevents Free Fatty Acid–Induced Insulin Resistance in Male Wistar Rats
Diabetes October 2001, Vol.50, 2316-2322. doi:https://doi.org/10.2337/diabetes.50.10.2316
Small Molecule Insulin Receptor Activators Potentiate Insulin Action in Insulin-Resistant Cells
Ming Li; Jack F. Youngren; Vara Prasad Manchem; Michael Kozlowski; Bei B. Zhang; Betty A. Maddux; Ira D. Goldfine
Diabetes October 2001, Vol.50, 2323-2328. doi:https://doi.org/10.2337/diabetes.50.10.2323
Intramyocellular Lipid Is Associated With Resistance to In Vivo Insulin Actions on Glucose Uptake, Antilipolysis, and Early Insulin Signaling Pathways in Human Skeletal Muscle
Antti Virkamäki; Elena Korsheninnikova; Anneli Seppälä-Lindroos; Satu Vehkavaara; Takashi Goto; Juha Halavaara; Anna-Maija Häkkinen; Hannele Yki-Järvinen
Diabetes October 2001, Vol.50, 2337-2343. doi:https://doi.org/10.2337/diabetes.50.10.2337
Increased Lactate Release per Fat Cell in Normoglycemic First-Degree Relatives of Individuals With Type 2 Diabetes
Diabetes October 2001, Vol.50, 2344-2348. doi:https://doi.org/10.2337/diabetes.50.10.2344
Caffeine Ingestion Decreases Glucose Disposal During a Hyperinsulinemic-Euglycemic Clamp in Sedentary Humans
Diabetes October 2001, Vol.50, 2349-2354. doi:https://doi.org/10.2337/diabetes.50.10.2349
Complications
Hexosamine-Induced Fibronectin Protein Synthesis in Mesangial Cells Is Associated With Increases in cAMP Responsive Element Binding (CREB) Phosphorylation and Nuclear CREB: The Involvement of Protein Kinases A and C
Diabetes October 2001, Vol.50, 2355-2362. doi:https://doi.org/10.2337/diabetes.50.10.2355
Hyperglycemia Activates p53 and p53-Regulated Genes Leading to Myocyte Cell Death
Fabio Fiordaliso; Annarosa Leri; Daniela Cesselli; Federica Limana; Bijan Safai; Bernardo Nadal-Ginard; Piero Anversa; Jan Kajstura
Diabetes October 2001, Vol.50, 2363-2375. doi:https://doi.org/10.2337/diabetes.50.10.2363
Epidemiology
The Relation of Markers of Inflammation to the Development of Glucose Disorders in the Elderly: The Cardiovascular Health Study
Joshua I. Barzilay; Linn Abraham; Susan R. Heckbert; Mary Cushman; Lewis H. Kuller; Helaine E. Resnick; Russell P. Tracy
Diabetes October 2001, Vol.50, 2384-2389. doi:https://doi.org/10.2337/diabetes.50.10.2384
Genetics
A Major Gene Effect on Fasting Insulin and Insulin Sensitivity in Familial Combined Hyperlipidemia
Diabetes October 2001, Vol.50, 2396-2401. doi:https://doi.org/10.2337/diabetes.50.10.2396
Brief Genetics Report
Characterization of the Annexin I Gene and Evaluation of Its Role in Type 2 Diabetes
Diabetes October 2001, Vol.50, 2402-2405. doi:https://doi.org/10.2337/diabetes.50.10.2402
Analysis of the Coding and Promoter Regions of the Autoantigen IA-2 in Subjects With and Without Autoantibodies to IA-2
Diabetes October 2001, Vol.50, 2406-2409. doi:https://doi.org/10.2337/diabetes.50.10.2406
A Common Hormone-Sensitive Lipase i6 Gene Polymorphism Is Associated With Decreased Human Adipocyte Lipolytic Function
Johan Hoffstedt; Peter Arner; Martin Schalling; Nancy L. Pedersen; Selim Sengul; Susanne Ahlberg; Anastasia Iliadou; Catharina Lavebratt
Diabetes October 2001, Vol.50, 2410-2413. doi:https://doi.org/10.2337/diabetes.50.10.2410