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Issues
1 December 2001
ISSN 0012-1797
EISSN 1939-327X
Rapid Publication
Loss of the Antiangiogenic Pigment Epithelium-Derived Factor in Patients With Angiogenic Eye Disease
Joachim Spranger; Martin Osterhoff; Manja Reimann; Matthias Möhlig; Michael Ristow; Mary Kay Francis; Vincent Cristofalo; Hans-Peter Hammes; Gillian Smith; Michael Boulton; Andreas F.H. Pfeiffer
Topics:
angiogenesis
,
angiogenesis inhibitors
,
diabetic retinopathy
,
epithelium
,
eye
Diabetes December 2001, Vol.50, 2641-2645. doi:https://doi.org/10.2337/diabetes.50.12.2641
Characterization of Allelic and Nucleotide Variation Between the RAGE Gene on Chromosome 6 and a Homologous Pseudogene Sequence to Its 5′ Regulatory Region on Chromosome 3: Implications for Polymorphic Studies in Diabetes
Topics:
chromosomes, human, pair 3
,
chromosomes, human, pair 6
,
genes
,
nucleotides
,
polymerase chain reaction
Diabetes December 2001, Vol.50, 2646-2651. doi:https://doi.org/10.2337/diabetes.50.12.2646
Metabolism and Signal Transduction
Tissue-Specific Regulation of Mitochondrial and Cytoplasmic Protein Synthesis Rates by Insulin
Topics:
amino acids
,
heart
,
insulin
,
leucine
,
liver
Diabetes December 2001, Vol.50, 2652-2658. doi:https://doi.org/10.2337/diabetes.50.12.2652
Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb
Topics:
blood capillaries
,
insulin
,
glucose uptake
,
lack of exercise
,
rats
Diabetes December 2001, Vol.50, 2659-2665. doi:https://doi.org/10.2337/diabetes.50.12.2659
Interplay Between Galanin and Leptin in the Hypothalamic Control of Feeding via Corticotropin-Releasing Hormone and Neuropeptide Y
Gabriela E. Bergonzelli; François P. Pralong; Micheline Glauser; Claudia Cavadas; Eric Grouzmann; Rolf C. Gaillard
Topics:
galanin
,
hypothalamus
,
leptin
,
neurons
,
neuropeptide y
Diabetes December 2001, Vol.50, 2666-2672. doi:https://doi.org/10.2337/diabetes.50.12.2666
Convergence of Pre- and Postsynaptic Influences on Glucosensing Neurons in the Ventromedial Hypothalamic Nucleus
Diabetes December 2001, Vol.50, 2673-2681. doi:https://doi.org/10.2337/diabetes.50.12.2673
Physiologic Hyperinsulinemia Enhances Human Skeletal Muscle Perfusion by Capillary Recruitment
Matthew Coggins; Jonathan Lindner; Steve Rattigan; Linda Jahn; Elizabeth Fasy; Sanjiv Kaul; Eugene Barrett
Topics:
blood capillaries
,
diagnostic imaging
,
forearm
,
hyperinsulinism
,
infusion procedures
Diabetes December 2001, Vol.50, 2682-2690. doi:https://doi.org/10.2337/diabetes.50.12.2682
Immunology and Transplantation
Intrinsic Defects in the T-Cell Lineage Results in Natural Killer T-Cell Deficiency and the Development of Diabetes in the Nonobese Diabetic Mouse
Topics:
mice
,
mice, inbred nod
,
natural killer t-cells
,
scid mice
,
severe combined immunodeficiency
Diabetes December 2001, Vol.50, 2691-2699. doi:https://doi.org/10.2337/diabetes.50.12.2691
Protection From Type 1 Diabetes in the Face of High Levels of Activated Autoaggressive Lymphocytes in a Viral Transgenic Mouse Model Crossed to the SV129 Strain
Topics:
diabetes mellitus, type 1
,
lymphocytes
,
lymphocytic choriomeningitis virus
,
mice
,
mice, inbred c57bl
Diabetes December 2001, Vol.50, 2700-2708. doi:https://doi.org/10.2337/diabetes.50.12.2700
Effects of Streptozocin Diabetes and Diabetes Treatment by Islet Transplantation on In Vivo Insulin Signaling in Rat Heart
Luigi Laviola; Gaetana Belsanti; Alberto M. Davalli; Raffaele Napoli; Sebastio Perrini; Gordon C. Weir; Riccardo Giorgino; Francesco Giorgino
Topics:
1-phosphatidylinositol 3-kinase
,
antibodies
,
heart
,
immunoblotting
,
insulin
Diabetes December 2001, Vol.50, 2709-2720. doi:https://doi.org/10.2337/diabetes.50.12.2709
Islet Studies
Interleukin-1β Stimulation of c-Jun NH2-Terminal Kinase Activity in Insulin-Secreting Cells: Evidence for Cytoplasmic Restriction
Topics:
insulin
,
pancreatic beta cell
,
phosphotransferases
,
antibodies
,
cytoplasm
Diabetes December 2001, Vol.50, 2721-2728. doi:https://doi.org/10.2337/diabetes.50.12.2721
Selective Modification of Pyruvate Dehydrogenase Kinase Isoform Expression in Rat Pancreatic Islets Elicited by Starvation and Activation of Peroxisome Proliferator–Activated Receptor-α: Implications for Glucose-Stimulated Insulin Secretion
Topics:
endocrine pancreas
,
glucose
,
insulin secretion
,
peroxisome proliferator-activated receptors
,
protein isoforms
Diabetes December 2001, Vol.50, 2729-2736. doi:https://doi.org/10.2337/diabetes.50.12.2729
Phenotyping of Individual Pancreatic Islets Locates Genetic Defects in Stimulus Secretion Coupling to Niddm1i Within the Major Diabetes Locus in GK Rats
Topics:
arterial oxygen tension
,
glucose
,
insulin
,
rats
,
tolbutamide
Diabetes December 2001, Vol.50, 2737-2743. doi:https://doi.org/10.2337/diabetes.50.12.2737
γ-Interferon Signaling in Pancreatic β-Cells Is Persistent but Can Be Terminated by Overexpression of Suppressor of Cytokine Signaling-1
Topics:
cytokine
,
insulinoma
,
signal transduction
,
socs1 gene
,
suppressor of cytokine signaling 1 protein
Diabetes December 2001, Vol.50, 2744-2751. doi:https://doi.org/10.2337/diabetes.50.12.2744
Transgenic Overexpression of Hepatocyte Growth Factor in the β-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice
Adolfo García-Ocaña; Rupangi C. Vasavada; Ana Cebrian; Vasumathi Reddy; Karen K. Takane; Juan-Carlos López-Talavera; Andrew F. Stewart
Topics:
animals, transgenic
,
glucose
,
insulin
,
mice
,
mice, transgenic
Diabetes December 2001, Vol.50, 2752-2762. doi:https://doi.org/10.2337/diabetes.50.12.2752
p57KIP2 Expression in Normal Islet Cells and in Hyperinsulinism of Infancy
S. A. Kassem; I. Ariel; P. S. Thornton; K. Hussain; V. Smith; K. J. Lindley; A. Aynsley-Green; B. Glaser
Topics:
hyperinsulinism
,
insulin
,
insulin-like growth factor ii
,
endocrine pancreas
,
pancreas
Diabetes December 2001, Vol.50, 2763-2769. doi:https://doi.org/10.2337/diabetes.50.12.2763
Pathophysiology
Insulin Signal Transduction in Skeletal Muscle From Glucose-Intolerant Relatives With Type 2 Diabetes
Heidi Storgaard; Xiao Mei Song; Christine B. Jensen; Sten Madsbad; Marie Björnholm; Allan Vaag; Juleen R. Zierath
Topics:
1-phosphatidylinositol 3-kinase
,
diabetes mellitus, type 2
,
glucose
,
insulin
,
irs1 protein, human
Diabetes December 2001, Vol.50, 2770-2778. doi:https://doi.org/10.2337/diabetes.50.12.2770
Protection From Obesity and Insulin Resistance in Mice Overexpressing Human Apolipoprotein C1
Miek C. Jong; Peter J. Voshol; Martin Muurling; Vivian E.H. Dahlmans; Johannes A. Romijn; Hanno Pijl; Louis M. Havekes
Topics:
adipose tissue
,
bmipp
,
insulin resistance
,
mice
,
mice, transgenic
Diabetes December 2001, Vol.50, 2779-2785. doi:https://doi.org/10.2337/diabetes.50.12.2779
Overfeeding Rapidly Induces Leptin and Insulin Resistance
Topics:
insulin resistance
,
leptin
,
overnutrition
,
insulin
Diabetes December 2001, Vol.50, 2786-2791. doi:https://doi.org/10.2337/diabetes.50.12.2786
Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-κB
Angelika Bierhaus; Stephan Schiekofer; Markus Schwaninger; Martin Andrassy; Per M. Humpert; Jiang Chen; Mei Hong; Thomas Luther; Thomas Henle; Ingrid Klöting; Michael Morcos; Marion Hofmann; Hans Tritschler; Bernd Weigle; Michael Kasper; Mark Smith; George Perry; Ann-Marie Schmidt; David M. Stern; Hans-Ulrich Häring; Erwin Schleicher; Peter P. Nawroth
Topics:
albumins
,
rage
,
peptides
,
oligonucleotides
,
reverse transcriptase polymerase chain reaction
Diabetes December 2001, Vol.50, 2792-2808. doi:https://doi.org/10.2337/diabetes.50.12.2792
PPAR-α–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance
Michèle Guerre-Millo; Christine Rouault; Philippe Poulain; Jocelyne André; Vincent Poitout; Jeffrey M. Peters; Frank J. Gonzalez; Jean-Charles Fruchart; Gérard Reach; Bart Staels
Topics:
diet, high-fat
,
mice, knockout
,
peroxisome proliferator-activated receptors
,
diet
,
insulin
Diabetes December 2001, Vol.50, 2809-2814. doi:https://doi.org/10.2337/diabetes.50.12.2809
Plasma Glucose–Lowering Effect of Tramadol in Streptozotocin-Induced Diabetic Rats
Topics:
plasma glucose
,
rats
,
streptozocin
,
tramadol
Diabetes December 2001, Vol.50, 2815-2821. doi:https://doi.org/10.2337/diabetes.50.12.2815
Identification of Novel Genes Differentially Expressed in Omental Fat of Obese Subjects and Obese Type 2 Diabetic Patients
Helena Corominola; Laura J. Conner; Lisa S. Beavers; Robert A. Gadski; Dwayne Johnson; Jose F. Caro; Ronit Rafaeloff-Phail
Topics:
dna, complementary
,
genes
,
obesity
,
omentum
,
rna
Diabetes December 2001, Vol.50, 2822-2830. doi:https://doi.org/10.2337/diabetes.50.12.2822
Acute 2DG-Induced Glucoprivation or Dexamethasone Abolishes 2DG-Induced Glucoregulatory Responses to Subsequent Glucoprivation
Topics:
blood glucose
,
dexamethasone
,
hyperglycemic agents
,
rats
,
saline solutions
Diabetes December 2001, Vol.50, 2831-2836. doi:https://doi.org/10.2337/diabetes.50.12.2831
Complications
Effects of Insulin and Antioxidant on Plasma 8-Hydroxyguanine and Tissue 8-Hydroxydeoxyguanosine in Streptozotocin-Induced Diabetic Rats
Kyong Soo Park; Jae Hyeon Kim; Min Seon Kim; Jeong Mi Kim; Suk Kyeong Kim; Jeong Yun Choi; Myung Hee Chung; Boghee Han; Seong Yeon Kim; Hong Kye Lee
Topics:
antioxidants
,
insulin
,
plasma
,
streptozocin
,
8-hydroxy-2'-deoxyguanosine
Diabetes December 2001, Vol.50, 2837-2841. doi:https://doi.org/10.2337/diabetes.50.12.2837
A Nonlinear Effect of Hyperglycemia and Current Cigarette Smoking Are Major Determinants of the Onset of Microalbuminuria in Type 1 Diabetes
Laura J. Scott; James H. Warram; Linda S. Hanna; Lori M. B. Laffel; Louise Ryan; Andrzej S. Krolewski
Topics:
follow-up
,
hemoglobin a, glycosylated
,
hyperglycemia
,
microalbuminuria
,
diabetes mellitus, type 1
Diabetes December 2001, Vol.50, 2842-2849. doi:https://doi.org/10.2337/diabetes.50.12.2842
Genetics
Genome-Wide Linkage Analysis Assessing Parent-of-Origin Effects in the Inheritance of Type 2 Diabetes and BMI in Pima Indians
Topics:
alleles
,
body mass index procedure
,
chromosomes
,
diabetes mellitus, type 2
,
genes
Diabetes December 2001, Vol.50, 2850-2857. doi:https://doi.org/10.2337/diabetes.50.12.2850
HbA1c Levels Are Genetically Determined Even in Type 1 Diabetes: Evidence From Healthy and Diabetic Twins
Harold Snieder; Pamela A. Sawtell; Lesley Ross; James Walker; Tim D. Spector; R. David Graham Leslie
Topics:
hemoglobin a, glycosylated
,
twins
,
diabetes mellitus, type 1
,
glucose
Diabetes December 2001, Vol.50, 2858-2863. doi:https://doi.org/10.2337/diabetes.50.12.2858
A Missense Mutation of Pax4 Gene (R121W) Is Associated With Type 2 Diabetes in Japanese
Yoshinori Shimajiri; Tokio Sanke; Hiroto Furuta; Tadashi Hanabusa; Takayuki Nakagawa; Yoshio Fujitani; Yoshitaka Kajimoto; Nobuyuki Takasu; Kishio Nanjo
Topics:
diabetes mellitus, type 2
,
genes
,
heterozygote
,
homozygote
,
insulin
Diabetes December 2001, Vol.50, 2864-2869. doi:https://doi.org/10.2337/diabetes.50.12.2864
Brief Genetics Report
Uncoupling Protein 3 Content Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes
Patrick Schrauwen; Matthijs K.C. Hesselink; Ellen E. Blaak; Lars B. Borghouts; Gert Schaart; Wim H.M. Saris; Hans A. Keizer
Topics:
diabetes mellitus, type 2
,
skeletal muscles
,
uncoupling protein 3
,
insulin
,
plasma glucose
Diabetes December 2001, Vol.50, 2870-2873. doi:https://doi.org/10.2337/diabetes.50.12.2870
Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice
Salah-Eddine Lamhamedi-Cherradi; Olivier Boulard; Cristina Gonzalez; Najiby Kassis; Diane Damotte; Laure Eloy; Guy Fluteau; Matthieu Lévi-Strauss; Henri-Jean Garchon
Topics:
autoimmunity
,
cd28 antigens
,
cyclophosphamide
,
mice
,
mice, inbred nod
Diabetes December 2001, Vol.50, 2874-2878. doi:https://doi.org/10.2337/diabetes.50.12.2874
Diabetes-Associated HLA-DQ Genes and Birth Weight
Topics:
birth weight
,
diabetes mellitus, type 1
,
genes
,
hla-dq antigens
Diabetes December 2001, Vol.50, 2879-2882. doi:https://doi.org/10.2337/diabetes.50.12.2879
Tribute
Bruce R. Zimmerman, md: 1942–2001
Topics:
alpha omega trial
,
argentina
,
awards and prizes
,
brain
,
chemotherapy regimen
Diabetes December 2001, Vol.50, 2883. doi:https://doi.org/10.2337/diabetes.50.12.2883
Erratum
Erratum
Topics:
diabetes mellitus, type 2
,
nonesterified fatty acids
,
oxidation
,
plasma
,
serotonin antagonist and reuptake inhibitors
Diabetes December 2001, Vol.50, 2884. doi:https://doi.org/10.2337/diabetes.50.12.2884
