Skip Nav Destination
Issues
1 September 2001
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
The Neuropeptide Pituitary Adenylate Cyclase–Activating Polypeptide and Islet Function
Diabetes September 2001, Vol.50, 1959-1969. doi:https://doi.org/10.2337/diabetes.50.9.1959
Rapid Publication
A Role for Hormone-Sensitive Lipase in Glucose-Stimulated Insulin Secretion: A Study in Hormone-Sensitive Lipase-Deficient Mice
Diabetes September 2001, Vol.50, 1970-1975. doi:https://doi.org/10.2337/diabetes.50.9.1970
Immunology and Transplantation
Isolation and Functional Characterization of Recombinant GAD65 Autoantibodies Derived by IgG Repertoire Cloning From Patients With Type 1 Diabetes
Diabetes September 2001, Vol.50, 1976-1982. doi:https://doi.org/10.2337/diabetes.50.9.1976
Heme Oxygenase-1 Induction in Islet Cells Results in Protection From Apoptosis and Improved In Vivo Function After Transplantation
Antonello Pileggi; R. Damaris Molano; Thierry Berney; Pierre Cattan; Caterina Vizzardelli; Robert Oliver; Christopher Fraker; Camillo Ricordi; Ricardo L. Pastori; Fritz H. Bach; Luca Inverardi
Diabetes September 2001, Vol.50, 1983-1991. doi:https://doi.org/10.2337/diabetes.50.9.1983
Autoreactive Diabetogenic T-Cells in NOD Mice Can Efficiently Expand From a Greatly Reduced Precursor Pool
David V. Serreze; Ellis A. Johnson; Harold D. Chapman; Robert T. Graser; Michele P. Marron; Teresa P. DiLorenzo; Pablo Silveira; Yoshitaka Yoshimura; Stanley G. Nathenson; Sebastian Joyce
Diabetes September 2001, Vol.50, 1992-2000. doi:https://doi.org/10.2337/diabetes.50.9.1992
Islet Studies
Decrease in β-Cell Mass Leads to Impaired Pulsatile Insulin Secretion, Reduced Postprandial Hepatic Insulin Clearance, and Relative Hyperglucagonemia in the Minipig
Lise L. Kjems; Barbara M. Kirby; Elizabeth M. Welsh; Johannes D. Veldhuis; Marty Straume; Susan S. McIntyre; Dongchang Yang; Pierre Lefèbvre; Peter C. Butler
Diabetes September 2001, Vol.50, 2001-2012. doi:https://doi.org/10.2337/diabetes.50.9.2001
Calpains Play a Role in Insulin Secretion and Action
Seamus K. Sreenan; Yun-Ping Zhou; Kenichi Otani; Polly A. Hansen; Kevin P.M. Currie; Chien-Yuan Pan; Jean-Pyo Lee; Diane M. Ostrega; William Pugh; Yukio Horikawa; Nancy J. Cox; Craig L. Hanis; Charles F. Burant; Aaron P. Fox; Graeme I. Bell; Kenneth S. Polonsky
Diabetes September 2001, Vol.50, 2013-2020. doi:https://doi.org/10.2337/diabetes.50.9.2013
Expression of the Receptor Tyrosine Kinase KIT in Mature β-Cells and in the Pancreas in Development
Latif Rachdi; Lynda El Ghazi; Florence Bernex; Jean-Jacques Panthier; Paul Czernichow; Raphael Scharfmann
Diabetes September 2001, Vol.50, 2021-2028. doi:https://doi.org/10.2337/diabetes.50.9.2021
A Low-Affinity Ca2+-Dependent Association of Calmodulin With the Rab3A Effector Domain Inversely Correlates With Insulin Exocytosis
Hiroshi Kajio; Scott Olszewski; Philip J. Rosner; Matthew J. Donelan; Kieran F. Geoghegan; Christopher J. Rhodes
Diabetes September 2001, Vol.50, 2029-2039. doi:https://doi.org/10.2337/diabetes.50.9.2029
Overexpression of Metallothionein in Pancreatic β-Cells Reduces Streptozotocin-Induced DNA Damage and Diabetes
Diabetes September 2001, Vol.50, 2040-2046. doi:https://doi.org/10.2337/diabetes.50.9.2040
Pathophysiology
The Generalized Aminoaciduria Seen in Patients With Hepatocyte Nuclear Factor-1α Mutations Is a Feature of All Patients With Diabetes and Is Associated With Glucosuria
Coralie Bingham; Sian Ellard; Anthony J. Nicholls; Charles A. Pennock; John Allen; Alan J. James; Simon C. Satchell; Maurice B. Salzmann; Andrew T. Hattersley
Diabetes September 2001, Vol.50, 2047-2052. doi:https://doi.org/10.2337/diabetes.50.9.2047
Use of a cDNA Array for the Identification of Genes Induced in Islets of Suckling Rats by a High-Carbohydrate Nutritional Intervention
Diabetes September 2001, Vol.50, 2053-2060. doi:https://doi.org/10.2337/diabetes.50.9.2053
Adipocyte Produces Matrix Metalloproteinases 2 and 9: Involvement in Adipose Differentiation
Diabetes September 2001, Vol.50, 2080-2086. doi:https://doi.org/10.2337/diabetes.50.9.2080
Abnormal Glucose Handling by the Kidney in Response to Hypoglycemia in Type 1 Diabetes
Diabetes September 2001, Vol.50, 2087-2093. doi:https://doi.org/10.2337/diabetes.50.9.2087
PPARγ Ligands Increase Expression and Plasma Concentrations of Adiponectin, an Adipose-Derived Protein
Norikazu Maeda; Masahiko Takahashi; Tohru Funahashi; Shinji Kihara; Hitoshi Nishizawa; Ken Kishida; Hiroyuki Nagaretani; Morihiro Matsuda; Ryutaro Komuro; Noriyuki Ouchi; Hiroshi Kuriyama; Kikuko Hotta; Tadashi Nakamura; Iichiro Shimomura; Yuji Matsuzawa
Diabetes September 2001, Vol.50, 2094-2099. doi:https://doi.org/10.2337/diabetes.50.9.2094
Complications
Reduced Oral Wound Healing in the NOD Mouse Model for Type 1 Autoimmune Diabetes and Its Reversal by Epidermal Growth Factor Supplementation
Akos Nagy; Hiroyuki Nagashima; Seunghee Cha; Gregory E. Oxford; Tivadar Zelles; Ammon B. Peck; Michael G. Humphreys-Beher
Diabetes September 2001, Vol.50, 2100-2104. doi:https://doi.org/10.2337/diabetes.50.9.2100
Glucose and Palmitic Acid Induce Degeneration of Myofibrils and Modulate Apoptosis in Rat Adult Cardiomyocytes
Daniela Dyntar; Monika Eppenberger-Eberhardt; Kathrin Maedler; Martin Pruschy; Hans M. Eppenberger; Giatgen A. Spinas; Marc Y. Donath
Diabetes September 2001, Vol.50, 2105-2113. doi:https://doi.org/10.2337/diabetes.50.9.2105
Overexpression of Cu2+/Zn2+ Superoxide Dismutase Protects Against Early Diabetic Glomerular Injury in Transgenic Mice
Diabetes September 2001, Vol.50, 2114-2125. doi:https://doi.org/10.2337/diabetes.50.9.2114
Changes in Matrix Proteoglycans Induced by Insulin and Fatty Acids in Hepatic Cells May Contribute to Dyslipidemia of Insulin Resistance
Urban Olsson; Ann-Charlotte Egnell; Mariam Rodríguez Lee; Gunnel Östergren Lundén; Malin Lorentzon; Markku Salmivirta; Göran Bondjers; Germán Camejo
Diabetes September 2001, Vol.50, 2126-2132. doi:https://doi.org/10.2337/diabetes.50.9.2126
Depressed Levels of Ca2+-Cycling Proteins May Underlie Sarcoplasmic Reticulum Dysfunction in the Diabetic Heart
Diabetes September 2001, Vol.50, 2133-2138. doi:https://doi.org/10.2337/diabetes.50.9.2133
Human Fructosamine-3-Kinase: Purification, Sequencing, Substrate Specificity, and Evidence of Activity In Vivo
Diabetes September 2001, Vol.50, 2139-2147. doi:https://doi.org/10.2337/diabetes.50.9.2139
Skeletal Muscle of Stroke-Prone Spontaneously Hypertensive Rats Exhibits Reduced Insulin-Stimulated Glucose Transport and Elevated Levels of Caveolin and Flotillin
Declan J. James; Fiona Cairns; Ian P. Salt; Gregory J. Murphy; Anna F. Dominiczak; John M.C. Connell; Gwyn W. Gould
Diabetes September 2001, Vol.50, 2148-2156. doi:https://doi.org/10.2337/diabetes.50.9.2148
Brief Genetics Report
Mutational Screening of the CART Gene in Obese Children: Identifying a Mutation (Leu34Phe) Associated With Reduced Resting Energy Expenditure and Cosegregating With Obesity Phenotype in a Large Family
Emanuele Miraglia del Giudice; Nicola Santoro; Grazia Cirillo; Luigi D’Urso; Rosario Di Toro; Laura Perrone
Diabetes September 2001, Vol.50, 2157-2160. doi:https://doi.org/10.2337/diabetes.50.9.2157
Functional Significance of the UCSNP-43 Polymorphism in the CAPN10 Gene for Proinsulin Processing and Insulin Secretion in Nondiabetic Germans
Michael Stumvoll; Andreas Fritsche; Alexander Madaus; Norbert Stefan; Melanie Weisser; Fausto Machicao; Hans Häring
Diabetes September 2001, Vol.50, 2161-2163. doi:https://doi.org/10.2337/diabetes.50.9.2161
Role of Allelic Variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in Moderate-to-Severe Insulin Resistance of Women With Polycystic Ovary Syndrome
Samira Ait El Mkadem; Corinne Lautier; Françoise Macari; Nicolas Molinari; Patrick Lefèbvre; Eric Renard; Jean Christophe Gris; Gérard Cros; Jean Pierre Daurès; Jacques Bringer; Morris F. White; Florin Grigorescu
Diabetes September 2001, Vol.50, 2164-2168. doi:https://doi.org/10.2337/diabetes.50.9.2164
Association of a Novel Point Mutation (C159G) of the CTLA4 Gene With Type 1 Diabetes in West Africans but not in Chinese
Douglas Osei-Hyiaman; Lifang Hou; Ren Zhiyin; Zhang Zhiming; Haiquin Yu; Abena Agyeiwaa Amankwah; Shoji Harada
Diabetes September 2001, Vol.50, 2169-2171. doi:https://doi.org/10.2337/diabetes.50.9.2169
Genetic Variation in the Peroxisome Proliferator–Activated Receptor-γ2 Gene (Pro12Ala) Affects Metabolic Responses to Weight Loss and Subsequent Weight Regain
Barbara J. Nicklas; Elisabeth F.C. van Rossum; Dora M. Berman; Alice S. Ryan; Karen E. Dennis; Alan R. Shuldiner
Diabetes September 2001, Vol.50, 2172-2176. doi:https://doi.org/10.2337/diabetes.50.9.2172