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Issues
1 November 2002
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
While Tinkering With the β-Cell… Metabolic Regulatory Mechanisms and New Therapeutic Strategies: American Diabetes Association Lilly Lecture, 2001
Diabetes November 2002, Vol.51, 3141-3150. doi:https://doi.org/10.2337/diabetes.51.11.3141
Metabolism and Signal Transduction
Effects of Insulin Deficiency or Excess on Hepatic Gluconeogenic Flux During Glycogenolytic Inhibition in the Conscious Dog
Dale S. Edgerton; Sylvain Cardin; Catherine Pan; Doss Neal; Ben Farmer; Margaret Converse; Alan D. Cherrington.
Diabetes November 2002, Vol.51, 3151-3162. doi:https://doi.org/10.2337/diabetes.51.11.3151
Altered Myocellular and Abdominal Fat Partitioning Predict Disturbance in Insulin Action in HIV Protease Inhibitor-Related Lipodystrophy
Seng Khee Gan; Katherine Samaras; Campbell H. Thompson; Edward W. Kraegen; Andrew Carr; David A. Cooper; Donald J. Chisholm
Diabetes November 2002, Vol.51, 3163-3169. doi:https://doi.org/10.2337/diabetes.51.11.3163
Impact of Duration of Infusion and Choice of Isotope Label on Isotope Recycling in Glucose Homeostasis
Diabetes November 2002, Vol.51, 3170-3175. doi:https://doi.org/10.2337/diabetes.51.11.3170
Profiling Gene Transcription In Vivo Reveals Adipose Tissue as an Immediate Target of Tumor Necrosis Factor-α: Implications for Insulin Resistance
Hong Ruan; Philip D. G. Miles; Christine M. Ladd; Kenneth Ross; Todd R. Golub; Jerrold M. Olefsky; Harvey F. Lodish
Diabetes November 2002, Vol.51, 3176-3188. doi:https://doi.org/10.2337/diabetes.51.11.3176
Obesity Studies
Dissociation of Obesity and Impaired Glucose Disposal in Mice Overexpressing Acyl Coenzyme A:Diacylglycerol Acyltransferase 1 in White Adipose Tissue
Diabetes November 2002, Vol.51, 3189-3195. doi:https://doi.org/10.2337/diabetes.51.11.3189
Comparison of Central and Peripheral Administration of C75 on Food Intake, Body Weight, and Conditioned Taste Aversion
Diabetes November 2002, Vol.51, 3196-3201. doi:https://doi.org/10.2337/diabetes.51.11.3196
Immunology and Transplantation
The Role of Autoimmunity in Islet Allograft Destruction: Major Histocompatibility Complex Class II Matching Is Necessary for Autoimmune Destruction of Allogeneic Islet Transplants After T-Cell Costimulatory Blockade
Leila Makhlouf; Koji Kishimoto; Rex N. Smith; Reza Abdi; Maria Koulmanda; Henry J. Winn; Hugh Auchincloss, Jr; Mohamed H. Sayegh
Diabetes November 2002, Vol.51, 3202-3210. doi:https://doi.org/10.2337/diabetes.51.11.3202
Islet Studies
Uncoupling Protein 2 Knockout Mice Have Enhanced Insulin Secretory Capacity After a High-Fat Diet
Jamie W. Joseph; Vasilij Koshkin; Chen-Yu Zhang; Jing Wang; Bradford B. Lowell; Catherine B. Chan; Michael B. Wheeler
Diabetes November 2002, Vol.51, 3211-3219. doi:https://doi.org/10.2337/diabetes.51.11.3211
Vascularized Islet Cell Transplantation in Miniature Swine: Islet-Kidney Allografts Correct the Diabetic Hyperglycemia Induced by Total Pancreatectomy
Naoki Kumagai; John C. LaMattina; Chisako Kamano; Parsia A. Vagefi; Rolf N. Barth; John J. O’Neil; Shin Yamamoto; Shannon G. Moran; Ryu Utsugi; David H. Sachs; Kazuhiko Yamada
Diabetes November 2002, Vol.51, 3220-3228. doi:https://doi.org/10.2337/diabetes.51.11.3220
Glucagon Is Required for Early Insulin-Positive Differentiation in the Developing Mouse Pancreas
Krishna Prasadan; Erica Daume; Barry Preuett; Troy Spilde; Amina Bhatia; Hiroyuki Kobayashi; Mark Hembree; Pradip Manna; George K. Gittes
Diabetes November 2002, Vol.51, 3229-3236. doi:https://doi.org/10.2337/diabetes.51.11.3229
Induction of Autoimmune Diabetes Through Insulin (but Not GAD65) DNA Vaccination in Nonobese Diabetic and in RIP-B7.1 Mice
Wolfram Karges; Klaus Pechhold; Sascha Al Dahouk; Ines Riegger; Matthias Rief; Andrea Wissmann; Reinhold Schirmbeck; Christoph Barth; Bernhard O. Boehm
Diabetes November 2002, Vol.51, 3237-3244. doi:https://doi.org/10.2337/diabetes.51.11.3237
SERCA3 Ablation Does Not Impair Insulin Secretion but Suggests Distinct Roles of Different Sarcoendoplasmic Reticulum Ca2+ Pumps for Ca2+ Homeostasis in Pancreatic β-cells
Abdelilah Arredouani; Yves Guiot; Jean-Christophe Jonas; Lynne H. Liu; Myriam Nenquin; José A. Pertusa; Jacques Rahier; Jean-François Rolland; Gary E. Shull; Martine Stevens; Frank Wuytack; Jean-Claude Henquin; Patrick Gilon
Diabetes November 2002, Vol.51, 3245-3253. doi:https://doi.org/10.2337/diabetes.51.11.3245
The iddm4 Locus Segregates With Diabetes Susceptibility in Congenic WF.iddm4 Rats
John P. Mordes; Jean Leif; Stephen Novak; Cheryl DeScipio; Dale L. Greiner; Elizabeth P. Blankenhorn
Diabetes November 2002, Vol.51, 3254-3262. doi:https://doi.org/10.2337/diabetes.51.11.3254
Pathophysiology
Prevention of Hypoglycemia Using Risk Assessment With a Continuous Glucose Monitoring System
Diabetes November 2002, Vol.51, 3263-3273. doi:https://doi.org/10.2337/diabetes.51.11.3263
Complications
Reduction of the Accumulation of Advanced Glycation End Products by ACE Inhibition in Experimental Diabetic Nephropathy
Josephine M. Forbes; Mark E. Cooper; Vicki Thallas; Wendy C. Burns; Merlin C. Thomas; Gail C. Brammar; Fiona Lee; Sharon L. Grant; Louise M. Burrell; George Jerums; Tanya M. Osicka
Diabetes November 2002, Vol.51, 3274-3282. doi:https://doi.org/10.2337/diabetes.51.11.3274
ALT-946 and Aminoguanidine, Inhibitors of Advanced Glycation, Improve Severe Nephropathy in the Diabetic Transgenic (mREN-2)27 Rat
Jennifer L. Wilkinson-Berka; Darren J. Kelly; Suzanne M. Koerner; Kassie Jaworski; Belinda Davis; Vicki Thallas; Mark E. Cooper
Diabetes November 2002, Vol.51, 3283-3289. doi:https://doi.org/10.2337/diabetes.51.11.3283
Activation of Cyclin D1-Cdk4 and Cdk4-Directed Phosphorylation of RB Protein in Diabetic Mesangial Hypertrophy
Diabetes November 2002, Vol.51, 3290-3299. doi:https://doi.org/10.2337/diabetes.51.11.3290
Relationship of Phospholipid Transfer Protein Activity to HDL and Apolipoprotein B-Containing Lipoproteins in Subjects With and Without Type 1 Diabetes
Helen M. Colhoun; Marja-Riitta Taskinen; James D. Otvos; Paul van den Berg; John O’Connor; Arie Van Tol
Diabetes November 2002, Vol.51, 3300-3305. doi:https://doi.org/10.2337/diabetes.51.11.3300
Decreased Myocardial Perfusion Reserve in Diabetic Autonomic Neuropathy
Diabetes November 2002, Vol.51, 3306-3310. doi:https://doi.org/10.2337/diabetes.51.11.3306
STAT5 Activation Induced by Diabetic LDL Depends on LDL Glycation and Occurs Via src Kinase Activity
Maria Felice Brizzi; Patrizia Dentelli; Roberto Gambino; Sara Cabodi; Maurizio Cassader; Ada Castelli; Paola Defilippi; Luigi Pegoraro; Gianfranco Pagano
Diabetes November 2002, Vol.51, 3311-3317. doi:https://doi.org/10.2337/diabetes.51.11.3311
Genetics
Linkage and Association With Type 1 Diabetes on Chromosome 1q42
Kathryn G. Ewens; Lindsey N. Johnson; Beth Wapelhorst; Kristin O’Brien; Sarah Gutin; V. Anne Morrison; Craig Street; Simon G. Gregory; Richard S. Spielman; Patrick Concannon
Diabetes November 2002, Vol.51, 3318-3325. doi:https://doi.org/10.2337/diabetes.51.11.3318
No Association Between lck Gene Polymorphisms and Protein Level in Type 1 Diabetes
Solange Nervi; Sandra Nicodeme; Corinne Gartioux; Catherine Atlan; Marc Lathrop; Denis Reviron; Philippe Naquet; Fumihiko Matsuda; Jean Imbert; Bernard Vialettes
Diabetes November 2002, Vol.51, 3326-3330. doi:https://doi.org/10.2337/diabetes.51.11.3326
Brief Genetics Reports
A Functional Polymorphism in the Promoter of UCP2 Enhances Obesity Risk but Reduces Type 2 Diabetes Risk in Obese Middle-Aged Humans
Franz Krempler; Harald Esterbauer; Raimund Weitgasser; Christoph Ebenbichler; Josef R. Patsch; Karl Miller; Mingqiang Xie; Veronika Linnemayr; Hannes Oberkofler; Wolfgang Patsch
Diabetes November 2002, Vol.51, 3331-3335. doi:https://doi.org/10.2337/diabetes.51.11.3331
Association of IL4R Haplotypes With Type 1 Diabetes
Daniel B. Mirel; Ana Maria Valdes; Laura C. Lazzeroni; Rebecca L. Reynolds; Henry A. Erlich; Janelle A. Noble
Diabetes November 2002, Vol.51, 3336-3341. doi:https://doi.org/10.2337/diabetes.51.11.3336
Molecular Analysis of KCNJ10 on 1q as a Candidate Gene for Type 2 Diabetes in Pima Indians
Diabetes November 2002, Vol.51, 3342-3346. doi:https://doi.org/10.2337/diabetes.51.11.3342
Interleukin-18 Promoter Polymorphisms in Type 1 Diabetes
Adam Kretowski; Katarzyna Mironczuk; Anna Karpinska; Urszula Bojaryn; Maciej Kinalski; Zbigniew Puchalski; Ida Kinalska
Diabetes November 2002, Vol.51, 3347-3349. doi:https://doi.org/10.2337/diabetes.51.11.3347
