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Rapid Publication

Molecular Detection of Circulating β-Cells After Islet Transplantation

Beate Ritz-Laser; José Oberholzer; Christian Toso; Marie-Claude Brulhart; Katerina Zakrzewska; Frédéric Ris; Pascal Bucher; Philippe Morel; Jacques Philippe

Abstracts

View articletitled, Molecular Detection of Circulating β-Cells After Islet Transplantation

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Topics: insulin , islets of langerhans transplantation , reverse transcriptase polymerase chain reaction , rna, messenger , transplantation

Diabetes March 2002, Vol.51, 557-561. doi:https://doi.org/10.2337/diabetes.51.3.557

Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates

Dongmei Han; Xiumin Xu; Ricardo L. Pastori; Camillo Ricordi; Norma S. Kenyon

Abstracts

View articletitled, Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates

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Topics: gene expression , genes , lymphocytes , macaca mulatta , perforin

Diabetes March 2002, Vol.51, 562-566. doi:https://doi.org/10.2337/diabetes.51.3.562

Metabolism and Signal Transduction

Effect of AICAR Treatment on Glycogen Metabolism in Skeletal Muscle

William G. Aschenbach; Michael F. Hirshman; Nobuharu Fujii; Kei Sakamoto; Kirsten F. Howlett; Laurie J. Goodyear

Abstracts

View articletitled, Effect of AICAR Treatment on Glycogen Metabolism in Skeletal Muscle

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Topics: aica ribonucleotide , ampk , glycogen (starch) synthase , glycogen phosphorylase , glycogen

Diabetes March 2002, Vol.51, 567-573. doi:https://doi.org/10.2337/diabetes.51.3.567

Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb: Evidence for Passive Diffusion

Marianthe Hamilton-Wessler; Marilyn Ader; Melvin K. Dea; Donna Moore; Mette Loftager; Jan Markussen; Richard N. Bergman

Abstracts

View articletitled, Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb: Evidence for Passive Diffusion

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Topics: insulin , insulin analogs

Diabetes March 2002, Vol.51, 574-582. doi:https://doi.org/10.2337/diabetes.51.3.574

Caffeine-Induced Impairment of Insulin Action but Not Insulin Signaling in Human Skeletal Muscle Is Reduced by Exercise

Farah S.L. Thong; Wim Derave; Bente Kiens; Terry E. Graham; Birgitte Ursø; Jørgen F.P. Wojtaszewski; Bo F. Hansen; Erik A. Richter

Abstracts

View articletitled, Caffeine-Induced Impairment of Insulin Action but Not Insulin Signaling in Human Skeletal Muscle Is Reduced by Exercise

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Topics: caffeine , insulin , skeletal muscles , leg , glucose

Diabetes March 2002, Vol.51, 583-590. doi:https://doi.org/10.2337/diabetes.51.3.583

Human Skeletal Muscle Expresses a Glycogen-Targeting Subunit of PP1 That Is Identical to the Insulin-Sensitive Glycogen-Targeting Subunit G_L of Liver

Shonagh Munro; Daniel J.R. Cuthbertson; Joan Cunningham; Mark Sales; Patricia T.W. Cohen

Abstracts

View articletitled, Human Skeletal Muscle Expresses a Glycogen-Targeting Subunit of PP1 That Is Identical to the Insulin-Sensitive Glycogen-Targeting Subunit GL of Liver

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Topics: dna, complementary , glycogen , insulin , liver , mice

Diabetes March 2002, Vol.51, 591-598. doi:https://doi.org/10.2337/diabetes.51.3.591

Mechanism of Amino Acid-Induced Skeletal Muscle Insulin Resistance in Humans

Michael Krebs; Martin Krssak; Elisabeth Bernroider; Christian Anderwald; Attila Brehm; Martin Meyerspeer; Peter Nowotny; Erich Roth; Werner Waldhäusl; Michael Roden

Abstracts

View articletitled, Mechanism of Amino Acid-Induced Skeletal Muscle Insulin Resistance in Humans

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Topics: acute aortic syndrome , anabolic steroids , glucagon , glucose , hormones

Diabetes March 2002, Vol.51, 599-605. doi:https://doi.org/10.2337/diabetes.51.3.599

Fructose Improves the Ability of Hyperglycemia Per Se to Regulate Glucose Production in Type 2 Diabetes

Meredith Hawkins; Ilan Gabriely; Robert Wozniak; Cristian Vilcu; Harry Shamoon; Luciano Rossetti

Abstracts

View articletitled, Fructose Improves the Ability of Hyperglycemia Per Se to Regulate Glucose Production in Type 2 Diabetes

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Topics: diabetes mellitus, type 2 , fructose , glucose , hyperglycemia , infusion procedures

Diabetes March 2002, Vol.51, 606-614. doi:https://doi.org/10.2337/diabetes.51.3.606

Insulin and Isoproterenol Differentially Regulate Mitogen-Activated Protein Kinase-Dependent Na⁺-K⁺-2Cl⁻ Cotransporter Activity in Skeletal Muscle

Aidar R. Gosmanov; Donald B. Thomason

Abstracts

View articletitled, Insulin and Isoproterenol Differentially Regulate Mitogen-Activated Protein Kinase-Dependent Na+-K+-2Cl− Cotransporter Activity in Skeletal Muscle

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Topics: insulin , mitogen-activated protein kinase p38 , phosphorylation , skeletal muscles , isoproterenol

Diabetes March 2002, Vol.51, 615-623. doi:https://doi.org/10.2337/diabetes.51.3.615

Increased Fatty Acid Re-esterification by PEPCK Overexpression in Adipose Tissue Leads to Obesity Without Insulin Resistance

Sylvie Franckhauser; Sergio Muñoz; Anna Pujol; Alba Casellas; Efren Riu; Pedro Otaegui; Benli Su; Fatima Bosch

Abstracts

View articletitled, Increased Fatty Acid Re-esterification by PEPCK Overexpression in Adipose Tissue Leads to Obesity Without Insulin Resistance

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Topics: adipose tissue , mice , mice, transgenic , obesity , phosphoenolpyruvate carboxylase

Diabetes March 2002, Vol.51, 624-630. doi:https://doi.org/10.2337/diabetes.51.3.624

C₂-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes

Jie Mei; Lena Stenson Holst; Tova Rahn Landström; Cecilia Holm; David Brindley; Vincent Manganiello; Eva Degerman

Abstracts

View articletitled, C2-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes

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Topics: adipocytes , ceramides , insulin , lipolysis

Diabetes March 2002, Vol.51, 631-637. doi:https://doi.org/10.2337/diabetes.51.3.631

Immunology and Transplantation

Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice

Alex Rabinovitch; Wilma L. Suarez-Pinzon; A.M. James Shapiro; Ray V. Rajotte; Robert Power

Abstracts

View articletitled, Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice

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Topics: interleukin-2 , mice , mice, inbred nod , rapamycin , tissue transplants

Diabetes March 2002, Vol.51, 638-645. doi:https://doi.org/10.2337/diabetes.51.3.638

Genetic Risk Determines the Emergence of Diabetes-Associated Autoantibodies in Young Children

Antti Kupila; Päivi Keskinen; Tuula Simell; Satu Erkkilä; Paula Arvilommi; Sari Korhonen; Teija Kimpimäki; Minna Sjöroos; Matti Ronkainen; Jorma Ilonen; Mikael Knip; Olli Simell

Abstracts

View articletitled, Genetic Risk Determines the Emergence of Diabetes-Associated Autoantibodies in Young Children

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Topics: autoantibodies , child , genetic risk , diabetes mellitus, type 1

Diabetes March 2002, Vol.51, 646-651. doi:https://doi.org/10.2337/diabetes.51.3.646

Islet Studies

Dipeptidyl Peptidase IV-Resistant [d-Ala²]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats

Simon A. Hinke; Richard W. Gelling; Raymond A. Pederson; Susanne Manhart; Cuilan Nian; Hans-Ulrich Demuth; Christopher H.S. McIntosh

Abstracts

View articletitled, Dipeptidyl Peptidase IV-Resistant [d-Ala2]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats

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Topics: glucose , insulin , obesity , peptides , rats

Diabetes March 2002, Vol.51, 652-661. doi:https://doi.org/10.2337/diabetes.51.3.652

Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats

Isabelle Briaud; Cynthia L. Kelpe; Lisa M. Johnson; Phuong Oanh T. Tran; Vincent Poitout

Abstracts

View articletitled, Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats

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Topics: diet , diet, high-fat , glucose , insulin , insulin secretion

Diabetes March 2002, Vol.51, 662-668. doi:https://doi.org/10.2337/diabetes.51.3.662

Assessment of the Role of Interstitial Glucagon in the Acute Glucose Secretory Responsiveness of In Situ Pancreatic β-Cells

Karen Moens; Veerle Berger; Jung-Mo Ahn; Chris Van Schravendijk; Victor J. Hruby; Daniel Pipeleers; Frans Schuit

Abstracts

View articletitled, Assessment of the Role of Interstitial Glucagon in the Acute Glucose Secretory Responsiveness of In Situ Pancreatic β-Cells

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Topics: glucagon , glucose , insulin , pancreas , antagonists

Diabetes March 2002, Vol.51, 669-675. doi:https://doi.org/10.2337/diabetes.51.3.669

Peroxisomal Proliferator-Activated Receptor-γ Upregulates Glucokinase Gene Expression in β-Cells

Ha-il Kim; Ji-Young Cha; So-Youn Kim; Jae-woo Kim; Kyung Jin Roh; Je-Kyung Seong; Nam Taek Lee; Kang-Yell Choi; Kyung-Sup Kim; Yong-ho Ahn

Abstracts

View articletitled, Peroxisomal Proliferator-Activated Receptor-γ Upregulates Glucokinase Gene Expression in β-Cells

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Topics: peroxisome proliferator-activated receptors , troglitazone , glucokinase , glucose , ligands

Diabetes March 2002, Vol.51, 676-685. doi:https://doi.org/10.2337/diabetes.51.3.676

Gastrin Stimulates β-Cell Neogenesis and Increases Islet Mass From Transdifferentiated but Not From Normal Exocrine Pancreas Tissue

Ilse Rooman; Jessy Lardon; Luc Bouwens

Abstracts

View articletitled, Gastrin Stimulates β-Cell Neogenesis and Increases Islet Mass From Transdifferentiated but Not From Normal Exocrine Pancreas Tissue

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Topics: exocrine pancreas , infusion procedures , insulin , ligation , pancreas

Diabetes March 2002, Vol.51, 686-690. doi:https://doi.org/10.2337/diabetes.51.3.686

NFAT Regulates Insulin Gene Promoter Activity in Response to Synergistic Pathways Induced by Glucose and Glucagon-Like Peptide-1

Michael C. Lawrence; Harshika S. Bhatt; Richard A. Easom

Abstracts

View articletitled, NFAT Regulates Insulin Gene Promoter Activity in Response to Synergistic Pathways Induced by Glucose and Glucagon-Like Peptide-1

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Topics: genes , glucagon-like peptide 1 , glucose , insulin , transcription, genetic

Diabetes March 2002, Vol.51, 691-698. doi:https://doi.org/10.2337/diabetes.51.3.691

Primary In Vivo Oscillations of Metabolism in the Pancreas

Peter Bergsten; Johanna Westerlund; Per Liss; Per-Ola Carlsson

Abstracts

View articletitled, Primary In Vivo Oscillations of Metabolism in the Pancreas

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Topics: insulin , pancreas , arterial oxygen tension , metabolism , portugal

Diabetes March 2002, Vol.51, 699-703. doi:https://doi.org/10.2337/diabetes.51.3.699

Counteraction of Type 1 Diabetic Alterations by Engineering Skeletal Muscle to Produce Insulin: Insights From Transgenic Mice

Efren Riu; Alex Mas; Tura Ferre; Anna Pujol; Laurent Gros; Pedro Otaegui; Lluis Montoliu; Fatima Bosch

Abstracts

View articletitled, Counteraction of Type 1 Diabetic Alterations by Engineering Skeletal Muscle to Produce Insulin: Insights From Transgenic Mice

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Topics: insulin , mice, transgenic , skeletal muscles , streptozocin , glucose

Diabetes March 2002, Vol.51, 704-711. doi:https://doi.org/10.2337/diabetes.51.3.704

Unregulated Elevation of Glutamate Dehydrogenase Activity Induces Glutamine-Stimulated Insulin Secretion: Identification and Characterization of a GLUD1 Gene Mutation and Insulin Secretion Studies With MIN6 Cells Overexpressing the Mutant Glutamate Dehydrogenase

Yukio Tanizawa; Kazuaki Nakai; Terumasa Sasaki; Takatoshi Anno; Yasuharu Ohta; Hiroshi Inoue; Kiyosato Matsuo; Mayumi Koga; Susumu Furukawa; Yoshitomo Oka

Abstracts

View articletitled, Unregulated Elevation of Glutamate Dehydrogenase Activity Induces Glutamine-Stimulated Insulin Secretion: Identification and Characterization of a GLUD1 Gene Mutation and Insulin Secretion Studies With MIN6 Cells Overexpressing the Mutant Glutamate Dehydrogenase

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Topics: genes , glucose , glutamate dehydrogenase , glutamine , insulin secretion

Diabetes March 2002, Vol.51, 712-717. doi:https://doi.org/10.2337/diabetes.51.3.712

Pathophysiology

Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists

Ciaran P. Sewter; Fiona Blows; Antonio Vidal-Puig; Stephen O’Rahilly

Abstracts

View articletitled, Regional Differences in the Response of Human Pre-Adipocytes to PPARγ and RXRα Agonists

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Topics: agonists , rna, messenger , rosiglitazone , adipocytes , ligands

Diabetes March 2002, Vol.51, 718-723. doi:https://doi.org/10.2337/diabetes.51.3.718

Hypoglycemia-Associated Autonomic Failure in Advanced Type 2 Diabetes

Scott A. Segel; Deanna S. Paramore; Philip E. Cryer

Abstracts

View articletitled, Hypoglycemia-Associated Autonomic Failure in Advanced Type 2 Diabetes

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Topics: diabetes mellitus, type 2 , hypoglycemia , insulin , hypoglycemic agents , glucagon

Diabetes March 2002, Vol.51, 724-733. doi:https://doi.org/10.2337/diabetes.51.3.724

Systemic and Local Adrenergic Regulation of Muscle Glucose Utilization During Hypoglycemia in Healthy Subjects

Robert P. Hoffman; Christine A. Sinkey; John M. Dopp; Bradley G. Phillips

Abstracts

View articletitled, Systemic and Local Adrenergic Regulation of Muscle Glucose Utilization During Hypoglycemia in Healthy Subjects

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Topics: glucose , hypoglycemia , insulin , infusion procedures , blood glucose normal

Diabetes March 2002, Vol.51, 734-742. doi:https://doi.org/10.2337/diabetes.51.3.734

Increased Insulin Sensitivity in IGF-I Receptor–Deficient Brown Adipocytes

Cecilia Mur; Angela M. Valverde; C. Ronald Kahn; Manuel Benito

Abstracts

View articletitled, Increased Insulin Sensitivity in IGF-I Receptor–Deficient Brown Adipocytes

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Topics: adipocytes , insulin , irs1 protein, human , insulin-like growth factor i , tyrosine

Diabetes March 2002, Vol.51, 743-754. doi:https://doi.org/10.2337/diabetes.51.3.743

Extreme Insulin Resistance of the Central Adipose Depot In Vivo

Steven D. Mittelman; Gregg W. Van Citters; Erlinda L. Kirkman; Richard N. Bergman

Abstracts

View articletitled, Extreme Insulin Resistance of the Central Adipose Depot In Vivo

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Topics: glucose , infusion procedures , insulin , omentum , insulin resistance

Diabetes March 2002, Vol.51, 755-761. doi:https://doi.org/10.2337/diabetes.51.3.755

Albumin Binding of Acylated Insulin (NN304) Does Not Deter Action to Stimulate Glucose Uptake

Melvin K. Dea; Marianthe Hamilton-Wessler; Marilyn Ader; Donna Moore; Lauge Schäffer; Mette Loftager; Aage Vølund; Richard N. Bergman

Abstracts

View articletitled, Albumin Binding of Acylated Insulin (NN304) Does Not Deter Action to Stimulate Glucose Uptake

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Topics: albumins , insulin , plasma

Diabetes March 2002, Vol.51, 762-769. doi:https://doi.org/10.2337/diabetes.51.3.762

Unprocessed Proinsulin Promotes Cell Survival During Neurulation in the Chick Embryo

Catalina Hernández-Sánchez; Eva Rubio; José Serna; Enrique J. de la Rosa; Flora de Pablo

Abstracts

View articletitled, Unprocessed Proinsulin Promotes Cell Survival During Neurulation in the Chick Embryo

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Topics: chick embryo , embryo , glucose , insulin , proinsulin

Diabetes March 2002, Vol.51, 770-777. doi:https://doi.org/10.2337/diabetes.51.3.770

Attenuation of Diabetic Hyperphagia in Neuropeptide Y–Deficient Mice

Dana K. Sindelar; Paul Mystkowski; Donald J. Marsh; Richard D. Palmiter; Michael W. Schwartz

Abstracts

View articletitled, Attenuation of Diabetic Hyperphagia in Neuropeptide Y–Deficient Mice

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Topics: fasting , mice , neuropeptide y , rna, messenger , streptozocin

Diabetes March 2002, Vol.51, 778-783. doi:https://doi.org/10.2337/diabetes.51.3.778

The Fate of [U-¹³C]Palmitate Extracted by Skeletal Muscle in Subjects With Type 2 Diabetes and Control Subjects

Ellen E. Blaak; Anton J.M. Wagenmakers

Abstracts

View articletitled, The Fate of [U-13C]Palmitate Extracted by Skeletal Muscle in Subjects With Type 2 Diabetes and Control Subjects

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Topics: carbon dioxide , infusion procedures , palmitates , skeletal muscles , glutamine

Diabetes March 2002, Vol.51, 784-789. doi:https://doi.org/10.2337/diabetes.51.3.784

Theophylline Improves Hypoglycemia Unawareness in Type 1 Diabetes

Bastiaan E. de Galan; Cees J. Tack; Jacques W. Lenders; Jaco W. Pasman; Lammy D. Elving; Frans G. Russel; Jos A. Lutterman; Paul Smits

Abstracts

View articletitled, Theophylline Improves Hypoglycemia Unawareness in Type 1 Diabetes

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Topics: glucose , hypoglycemia , hypoglycemia unawareness , hypoglycemic agents , theophylline

Diabetes March 2002, Vol.51, 790-796. doi:https://doi.org/10.2337/diabetes.51.3.790

The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes

Adam B. Mayerson; Ripudaman S. Hundal; Sylvie Dufour; Vincent Lebon; Douglas Befroy; Gary W. Cline; Staffan Enocksson; Silvio E. Inzucchi; Gerald I. Shulman; Kitt F. Petersen

Abstracts

View articletitled, The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes

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Topics: calorimetry, indirect , diabetes mellitus, type 2 , glucose , glycerol , insulin

Diabetes March 2002, Vol.51, 797-802. doi:https://doi.org/10.2337/diabetes.51.3.797

Complications

Association of Fasting Plasma Glucose With Heart Rate Recovery in Healthy Adults: A Population-Based Study

Claudia Panzer; Michael S. Lauer; Andreas Brieke; Eugene Blackstone; Byron Hoogwerf

Abstracts

View articletitled, Association of Fasting Plasma Glucose With Heart Rate Recovery in Healthy Adults: A Population-Based Study

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Topics: fasting , heart-rate recovery , plasma glucose , exercise stress test

Diabetes March 2002, Vol.51, 803-807. doi:https://doi.org/10.2337/diabetes.51.3.803

Effects of Treatment With Sulfonylurea Drugs or Insulin on Ischemia-Induced Myocardial Dysfunction in Type 2 Diabetes

Roldano Scognamiglio; Angelo Avogaro; Saula Vigili de Kreutzenberg; Christian Negut; Monica Palisi; Eros Bagolin; Antonio Tiengo

Abstracts

View articletitled, Effects of Treatment With Sulfonylurea Drugs or Insulin on Ischemia-Induced Myocardial Dysfunction in Type 2 Diabetes

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Topics: diabetes mellitus, type 2 , dipyridamole , echocardiography , glyburide , insulin

Diabetes March 2002, Vol.51, 808-812. doi:https://doi.org/10.2337/diabetes.51.3.808

Coronary Microvascular Adaptation to Myocardial Metabolic Demand Can Be Restored by Inhibition of Iron-Catalyzed Formation of Oxygen Free Radicals in Type 2 Diabetic Patients

Alain Nitenberg; Séverine Ledoux; Paul Valensi; Régis Sachs; Isabelle Antony

Abstracts

View articletitled, Coronary Microvascular Adaptation to Myocardial Metabolic Demand Can Be Restored by Inhibition of Iron-Catalyzed Formation of Oxygen Free Radicals in Type 2 Diabetic Patients

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Topics: coronary angiography , coronary artery , coronary artery flow , dilatation, pathologic , free radicals

Diabetes March 2002, Vol.51, 813-818. doi:https://doi.org/10.2337/diabetes.51.3.813

Morphometry of Dorsal Root Ganglion in Chronic Experimental Diabetic Neuropathy

Motoko Kishi; James Tanabe; James D. Schmelzer; Phillip A. Low

Abstracts

View articletitled, Morphometry of Dorsal Root Ganglion in Chronic Experimental Diabetic Neuropathy

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Topics: diabetic neuropathies , ganglia, spinal , neurons , rats

Diabetes March 2002, Vol.51, 819-824. doi:https://doi.org/10.2337/diabetes.51.3.819

Genetics

Deconstructing and Reconstructing Obesity-Induced Diabetes (Diabesity) in Mice

Peter C. Reifsnyder; Edward H. Leiter

Abstracts

View articletitled, Deconstructing and Reconstructing Obesity-Induced Diabetes (Diabesity) in Mice

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Topics: mice , obesity , quantitative trait loci , weight gain , phenotype

Diabetes March 2002, Vol.51, 825-832. doi:https://doi.org/10.2337/diabetes.51.3.825

A Genome-Wide Scan for Loci Linked to Plasma Levels of Glucose and HbA_1c in a Community-Based Sample of Caucasian Pedigrees: The Framingham Offspring Study

James B. Meigs; Carolien I. M. Panhuysen; Richard H. Myers; Peter W.F. Wilson; L. Adrienne Cupples

Abstracts

View articletitled, A Genome-Wide Scan for Loci Linked to Plasma Levels of Glucose and HbA1c in a Community-Based Sample of Caucasian Pedigrees: The Framingham Offspring Study

Supplementary data

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Topics: fasting blood glucose measurement , genetic pedigree , glucose , hemoglobin a, glycosylated , genome

Diabetes March 2002, Vol.51, 833-840. doi:https://doi.org/10.2337/diabetes.51.3.833

Factors of Insulin Resistance Syndrome–Related Phenotypes Are Linked to Genetic Locations on Chromosomes 6 and 7 in Nondiabetic Mexican-Americans

Rector Arya; John Blangero; Ken Williams; Laura Almasy; Thomas D. Dyer; Robin J. Leach; Peter O’Connell; Michael P. Stern; Ravindranath Duggirala

Abstracts

View articletitled, Factors of Insulin Resistance Syndrome–Related Phenotypes Are Linked to Genetic Locations on Chromosomes 6 and 7 in Nondiabetic Mexican-Americans

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Topics: chromosomes , fibrinogen , genetics , insulin , insulin resistance

Diabetes March 2002, Vol.51, 841-847. doi:https://doi.org/10.2337/diabetes.51.3.841

A Genomewide Linkage Scan for Abdominal Subcutaneous and Visceral Fat in Black and White Families: The HERITAGE Family Study

Treva Rice; Yvon C. Chagnon; Louis Pérusse; Ingrid B. Borecki; Olavi Ukkola; Tuomo Rankinen; Jacques Gagnon; Arthur S. Leon; James S. Skinner; Jack H. Wilmore; Claude Bouchard; D.C. Rao

Abstracts

View articletitled, A Genomewide Linkage Scan for Abdominal Subcutaneous and Visceral Fat in Black and White Families: The HERITAGE Family Study

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Topics: abdomen , family studies , obesity , visceral fat , genes

Diabetes March 2002, Vol.51, 848-855. doi:https://doi.org/10.2337/diabetes.51.3.848

Brief Genetics Reports

A Genome-Wide Search for Linkage-Disequilibrium With Type 1 Diabetes in a Recent Genetically Isolated Population From the Netherlands

Norbert Vaessen; Peter Heutink; Jeanine J. Houwing-Duistermaat; Pieter J.L.M. Snijders; Tessa Rademaker; Leon Testers; Manou R. Batstra; Lodewijk A. Sandkuijl; Cornelia M. van Duijn; Ben A. Oostra

Abstracts

View articletitled, A Genome-Wide Search for Linkage-Disequilibrium With Type 1 Diabetes in a Recent Genetically Isolated Population From the Netherlands

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Topics: alleles , diabetes mellitus, type 1 , genome , human leukocyte antigens , netherlands

Diabetes March 2002, Vol.51, 856-859. doi:https://doi.org/10.2337/diabetes.51.3.856

Human Resistin Gene, Obesity, and Type 2 Diabetes: Mutation Analysis and Population Study

Federica Sentinelli; Stefano Romeo; Marcello Arca; Emanuela Filippi; Frida Leonetti; Michela Banchieri; Umberto Di Mario; Marco Giorgio Baroni

Abstracts

View articletitled, Human Resistin Gene, Obesity, and Type 2 Diabetes: Mutation Analysis and Population Study

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Topics: diabetes mellitus, type 2 , genes , obesity , resistin , insulin

Diabetes March 2002, Vol.51, 860-862. doi:https://doi.org/10.2337/diabetes.51.3.860

Systematic Search for Single Nucleotide Polymorphisms in the Resistin Gene: The Absence of Evidence for the Association of Three Identified Single Nucleotide Polymorphisms With Japanese Type 2 Diabetes

Haruhiko Osawa; Hiroshi Onuma; Akiko Murakami; Masaaki Ochi; Tatsuya Nishimiya; Kenichi Kato; Ikki Shimizu; Yasuhisa Fujii; Jun Ohashi; Hideichi Makino

Abstracts

View articletitled, Systematic Search for Single Nucleotide Polymorphisms in the Resistin Gene: The Absence of Evidence for the Association of Three Identified Single Nucleotide Polymorphisms With Japanese Type 2 Diabetes

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Topics: diabetes mellitus, type 2 , genes , resistin , single nucleotide polymorphism , insulin

Diabetes March 2002, Vol.51, 863-866. doi:https://doi.org/10.2337/diabetes.51.3.863

The Proline 12 Alanine Substitution in the Peroxisome Proliferator–Activated Receptor-γ2 Gene Is Associated With Lower Lipoprotein Lipase Activity in Vivo

Jochen Schneider; Joerg Kreuzer; Andreas Hamann; Peter P. Nawroth; Klaus A. Dugi

Abstracts

View articletitled, The Proline 12 Alanine Substitution in the Peroxisome Proliferator–Activated Receptor-γ2 Gene Is Associated With Lower Lipoprotein Lipase Activity in Vivo

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Topics: alanine , alleles , genes , lipoprotein lipase , peroxisome

Diabetes March 2002, Vol.51, 867-870. doi:https://doi.org/10.2337/diabetes.51.3.867

Relationship Between TaqIB Cholesteryl Ester Transfer Protein Gene Polymorphism and Macrovascular Complications in Japanese Patients With Type 2 Diabetes

Isao Kawasaki; Hideki Tahara; Masanori Emoto; Tetsuo Shoji; Yoshiki Nishizawa

Abstracts

View articletitled, Relationship Between TaqIB Cholesteryl Ester Transfer Protein Gene Polymorphism and Macrovascular Complications in Japanese Patients With Type 2 Diabetes

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Topics: cholesterol ester transfer proteins , polymorphism , diabetes mellitus, type 2 , genes , high density lipoprotein cholesterol

Diabetes March 2002, Vol.51, 871-874. doi:https://doi.org/10.2337/diabetes.51.3.871

K_IR6.2 Polymorphism Predisposes to Type 2 Diabetes by Inducing Overactivity of Pancreatic β-Cell ATP-Sensitive K⁺ Channels

Christina Schwanstecher; Ulrike Meyer; Mathias Schwanstecher

Abstracts

View articletitled, KIR6.2 Polymorphism Predisposes to Type 2 Diabetes by Inducing Overactivity of Pancreatic β-Cell ATP-Sensitive K+ Channels

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Topics: diabetes mellitus, type 2 , pancreas , polymorphism , abcc8 gene , heterozygote

Diabetes March 2002, Vol.51, 875-879. doi:https://doi.org/10.2337/diabetes.51.3.875

Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin Resistance: Evidence of Interaction With the Trp64Arg Variant of the β-3-Adrenergic Receptor

Daniela Mentuccia; Laura Proietti-Pannunzi; Keith Tanner; Vincenzo Bacci; Toni I. Pollin; Eric T. Poehlman; Alan R. Shuldiner; Francesco S. Celi

Abstracts

View articletitled, Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin Resistance: Evidence of Interaction With the Trp64Arg Variant of the β-3-Adrenergic Receptor

Supplementary data

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Topics: genes , insulin resistance , iodide peroxidase , obesity , thyroid hormones

Diabetes March 2002, Vol.51, 880-883. doi:https://doi.org/10.2337/diabetes.51.3.880

Variations in Insulin Secretion in Carriers of Gene Variants in IRS-1 and -2

Leen M. ’t Hart; Giel Nijpels; Jacqueline M. Dekker; J. Antonie Maassen; Robert J. Heine; Timon W. van Haeften

Abstracts

View articletitled, Variations in Insulin Secretion in Carriers of Gene Variants in IRS-1 and -2

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Topics: genes , glucose , hyperglycemic agents , insulin secretion , irs1 protein, human

Diabetes March 2002, Vol.51, 884-887. doi:https://doi.org/10.2337/diabetes.51.3.884

Letter to the Editor

Status of Research Funded by the American Diabetes Association: Year 3

Mayer B. Davidson, MD

Abstracts

View articletitled, Status of Research Funded by the American Diabetes Association: Year 3

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Topics: awards and prizes

Diabetes March 2002, Vol.51, 888. doi:https://doi.org/10.2337/diabetes.51.3.888

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