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Issues
1 June 2002
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Genetic Studies of Late Diabetic Complications: The Overlooked Importance of Diabetes Duration Before Complication Onset
Diabetes June 2002, Vol.51, 1655-1662. doi:https://doi.org/10.2337/diabetes.51.6.1655
Metabolism
Role of the Insulin Receptor Substrate 1 and Phosphatidylinositol 3-Kinase Signaling Pathway in Insulin-Induced Expression of Sterol Regulatory Element Binding Protein 1c and Glucokinase Genes in Rat Hepatocytes
Michihiro Matsumoto; Wataru Ogawa; Kiyoshi Teshigawara; Hiroshi Inoue; Kazuaki Miyake; Hiroshi Sakaue; Masato Kasuga
Diabetes June 2002, Vol.51, 1672-1680. doi:https://doi.org/10.2337/diabetes.51.6.1672
Amino Acid Kinetics During the Anhepatic Phase of Liver Transplantation
Alberto Battezzati; Andrea Caumo; Annalisa Fattorini; Lucia Piceni Sereni; Jorgelina Coppa; Raffaele Romito; Mario Ammatuna; Enrico Regalia; Vincenzo Mazzaferro; Livio Luzi
Diabetes June 2002, Vol.51, 1690-1698. doi:https://doi.org/10.2337/diabetes.51.6.1690
Mature Adipocytes Inhibit In Vitro Differentiation of Human Preadipocytes via Angiotensin Type 1 Receptors
Diabetes June 2002, Vol.51, 1699-1707. doi:https://doi.org/10.2337/diabetes.51.6.1699
A Nuclear Magnetic Resonance-Based Demonstration of Substantial Oxidative l-Alanine Metabolism and l-Alanine-Enhanced Glucose Metabolism in a Clonal Pancreatic β-Cell Line : Metabolism of l-Alanine Is Important to the Regulation of Insulin Secretion
Lorraine Brennan; Aine Shine; Chandralal Hewage; J. Paul G. Malthouse; Kevin M. Brindle; Neville McClenaghan; Peter R. Flatt; Philip Newsholme
Diabetes June 2002, Vol.51, 1714-1721. doi:https://doi.org/10.2337/diabetes.51.6.1714
Sterol Regulatory Element Binding Protein-1c Expression and Action in Rat Muscles: Insulin-Like Effects on the Control of Glycolytic and Lipogenic Enzymes and UCP3 Gene Expression
Isabelle Guillet-Deniau; Virginie Mieulet; Soazig Le Lay; Younes Achouri; Denis Carré; Jean Girard; Fabienne Foufelle; Pascal Ferré
Diabetes June 2002, Vol.51, 1722-1728. doi:https://doi.org/10.2337/diabetes.51.6.1722
Obesity
Humoral Regulation of Resistin Expression in 3T3-L1 and Mouse Adipose Cells
Nobuhiro Shojima; Hideyuki Sakoda; Takehide Ogihara; Midori Fujishiro; Hideki Katagiri; Motonobu Anai; Yukiko Onishi; Hiraku Ono; Kouichi Inukai; Miho Abe; Yasushi Fukushima; Masatoshi Kikuchi; Yoshitomo Oka; Tomoichiro Asano
Diabetes June 2002, Vol.51, 1737-1744. doi:https://doi.org/10.2337/diabetes.51.6.1737
Immunology
Islet
Inhibition of Interleukin-1β-Induced COX-2 and EP3 Gene Expression by Sodium Salicylate Enhances Pancreatic Islet β-Cell Function
Diabetes June 2002, Vol.51, 1772-1778. doi:https://doi.org/10.2337/diabetes.51.6.1772
Hepatocyte Nuclear Factor-1α Modulates Pancreatic β-Cell Growth by Regulating the Expression of Insulin-Like Growth Factor-1 in INS-1 Cells
Qin Yang; Kazuya Yamagata; Kenji Fukui; Yang Cao; Takao Nammo; Hiromi Iwahashi; Haiyan Wang; Itaru Matsumura; Toshiaki Hanafusa; Richard Bucala; Claes B. Wollheim; Jun-ichiro Miyagawa; Yuji Matsuzawa
Diabetes June 2002, Vol.51, 1785-1792. doi:https://doi.org/10.2337/diabetes.51.6.1785
Overexpression of c-Myc in β-Cells of Transgenic Mice Causes Proliferation and Apoptosis, Downregulation of Insulin Gene Expression, and Diabetes
D. Ross Laybutt; Gordon C. Weir; Hideaki Kaneto; Judith Lebet; Richard D. Palmiter; Arun Sharma; Susan Bonner-Weir
Diabetes June 2002, Vol.51, 1793-1804. doi:https://doi.org/10.2337/diabetes.51.6.1793
cFLIP Protein Prevents Tumor Necrosis Factor-α–Mediated Induction of Caspase-8–Dependent Apoptosis in Insulin-Secreting βTc-Tet Cells
Diabetes June 2002, Vol.51, 1805-1814. doi:https://doi.org/10.2337/diabetes.51.6.1805
The Composition of Dietary Fat Directly Influences Glucose-Stimulated Insulin Secretion in Rats
Robert L. Dobbins; Lidia S. Szczepaniak; Jeff Myhill; Yoshifumi Tamura; Hiroshi Uchino; Adria Giacca; J. Denis McGarry
Diabetes June 2002, Vol.51, 1825-1833. doi:https://doi.org/10.2337/diabetes.51.6.1825
Pathophysiology
Antidiabetic Effects of Panax ginseng Berry Extract and the Identification of an Effective Component
Anoja S. Attele; Yun-Ping Zhou; Jing-Tian Xie; Ji An Wu; Liu Zhang; Lucy Dey; William Pugh; Paul A. Rue; Kenneth S. Polonsky; Chun-Su Yuan
Diabetes June 2002, Vol.51, 1851-1858. doi:https://doi.org/10.2337/diabetes.51.6.1851
Tanis: A Link Between Type 2 Diabetes and Inflammation?
Ken Walder; Lakshmi Kantham; Janine S. McMillan; James Trevaskis; Lyndal Kerr; Andrea de Silva; Terry Sunderland; Nathan Godde; Yuan Gao; Natalie Bishara; Kelly Windmill; Janette Tenne-Brown; Guy Augert; Paul Z. Zimmet; Greg R. Collier
Diabetes June 2002, Vol.51, 1859-1866. doi:https://doi.org/10.2337/diabetes.51.6.1859
Altered Tumor Necrosis Factor-α (TNF-α) Processing in Adipocytes and Increased Expression of Transmembrane TNF-α in Obesity
Diabetes June 2002, Vol.51, 1876-1883. doi:https://doi.org/10.2337/diabetes.51.6.1876
Plasma Adiponectin Concentration Is Associated With Skeletal Muscle Insulin Receptor Tyrosine Phosphorylation, and Low Plasma Concentration Precedes a Decrease in Whole-Body Insulin Sensitivity in Humans
Norbert Stefan; Barbora Vozarova; Tohru Funahashi; Yuji Matsuzawa; Christian Weyer; Robert S. Lindsay; Jack F. Youngren; Peter J. Havel; Richard E. Pratley; Clifton Bogardus; P. Antonio Tataranni
Diabetes June 2002, Vol.51, 1884-1888. doi:https://doi.org/10.2337/diabetes.51.6.1884
High Alanine Aminotransferase Is Associated With Decreased Hepatic Insulin Sensitivity and Predicts the Development of Type 2 Diabetes
Barbora Vozarova; Norbert Stefan; Robert S. Lindsay; Aramesh Saremi; Richard E. Pratley; Clifton Bogardus; P. Antonio Tataranni
Diabetes June 2002, Vol.51, 1889-1895. doi:https://doi.org/10.2337/diabetes.51.6.1889
The Novel Diazoxide Analog 3-Isopropylamino-7-Methoxy-4H-1,2,4-Benzothiadiazine 1,1-Dioxide Is a Selective Kir6.2/SUR1 Channel Opener
Michael Dabrowski; Frances M. Ashcroft; Rebecca Ashfield; Philippe Lebrun; Bernard Pirotte; Jan Egebjerg; John Bondo Hansen; Philip Wahl
Diabetes June 2002, Vol.51, 1896-1906. doi:https://doi.org/10.2337/diabetes.51.6.1896
Female Rats Do Not Exhibit Free Fatty Acid–Induced Insulin Resistance
Diabetes June 2002, Vol.51, 1907-1912. doi:https://doi.org/10.2337/diabetes.51.6.1907
Gene Expression Profile in Skeletal Muscle of Type 2 Diabetes and the Effect of Insulin Treatment
Diabetes June 2002, Vol.51, 1913-1920. doi:https://doi.org/10.2337/diabetes.51.6.1913
Differential Effects of Tumor Necrosis Factor-α on Protein Kinase C Isoforms α and δ Mediate Inhibition of Insulin Receptor Signaling
Diabetes June 2002, Vol.51, 1921-1930. doi:https://doi.org/10.2337/diabetes.51.6.1921
Complications
Interleukin-10 Protects Nitric Oxide–Dependent Relaxation During Diabetes: Role of Superoxide
Diabetes June 2002, Vol.51, 1931-1937. doi:https://doi.org/10.2337/diabetes.51.6.1931
Hyperglycemia-Induced Apoptosis in Mouse Myocardium: Mitochondrial Cytochrome c–Mediated Caspase-3 Activation Pathway
Diabetes June 2002, Vol.51, 1938-1948. doi:https://doi.org/10.2337/diabetes.51.6.1938
Lipoprotein Subclasses and Particle Sizes and Their Relationship With Coronary Artery Calcification in Men and Women With and Without Type 1 Diabetes
Helen M. Colhoun; James D. Otvos; Mike B. Rubens; M. R. Taskinen; S. Richard Underwood; John H. Fuller
Diabetes June 2002, Vol.51, 1949-1956. doi:https://doi.org/10.2337/diabetes.51.6.1949
Thrombomodulin Deficiency in Human Diabetic Nerve Microvasculature
Diabetes June 2002, Vol.51, 1957-1963. doi:https://doi.org/10.2337/diabetes.51.6.1957
Genetics
Enterovirus RNA Is Found in Peripheral Blood Mononuclear Cells in a Majority of Type 1 Diabetic Children at Onset
Diabetes June 2002, Vol.51, 1964-1971. doi:https://doi.org/10.2337/diabetes.51.6.1964
The Diabetes-Prone BB Rat Carries a Frameshift Mutation in Ian4, a Positional Candidate of Iddm1
Diabetes June 2002, Vol.51, 1972-1979. doi:https://doi.org/10.2337/diabetes.51.6.1972
Mutations in the Human Leptin and Leptin Receptor Genes as Models of Serum Leptin Receptor Regulation
Diabetes June 2002, Vol.51, 1980-1985. doi:https://doi.org/10.2337/diabetes.51.6.1980
Brief Genetics Report
Insertion/Deletion Polymorphism of the ACE Gene Is Associated With Type 2 Diabetes
Diabetes June 2002, Vol.51, 1986-1988. doi:https://doi.org/10.2337/diabetes.51.6.1986
An X-Chromosome Scan Reveals a Locus for Fat Distribution in Chromosome Region Xp21–22
Diabetes June 2002, Vol.51, 1989-1991. doi:https://doi.org/10.2337/diabetes.51.6.1989