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Issues
1 October 2003
ISSN 0012-1797
EISSN 1939-327X
Metabolism
Primacy of Hepatic Insulin Resistance in the Development of the Metabolic Syndrome Induced by an Isocaloric Moderate-Fat Diet in the Dog
Diabetes October 2003, Vol.52, 2453-2460. doi:https://doi.org/10.2337/diabetes.52.10.2453
A Sustained Increase in Plasma Free Fatty Acids Impairs Insulin Secretion in Nondiabetic Subjects Genetically Predisposed to Develop Type 2 Diabetes
Sangeeta Kashyap; Renata Belfort; Amalia Gastaldelli; Thongchai Pratipanawatr; Rachele Berria; Wilailak Pratipanawatr; Mandeep Bajaj; Lawrence Mandarino; Ralph DeFronzo; Kenneth Cusi
Diabetes October 2003, Vol.52, 2461-2474. doi:https://doi.org/10.2337/diabetes.52.10.2461
Measurement of Fractional Whole-Body Gluconeogenesis in Humans From Blood Samples Using 2H Nuclear Magnetic Resonance Spectroscopy
O. Kunert; H. Stingl; E. Rosian; M. Krššák; E. Bernroider; W. Seebacher; K. Zangger; P. Staehr; V. Chandramouli; B.R. Landau; P. Nowotny; W. Waldhäusl; E. Haslinger; M. Roden
Diabetes October 2003, Vol.52, 2475-2482. doi:https://doi.org/10.2337/diabetes.52.10.2475
Signal Transduction
Insulin Resistance in the Liver-Specific IGF-1 Gene-Deleted Mouse Is Abrogated by Deletion of the Acid-Labile Subunit of the IGF-Binding Protein-3 Complex: Relative Roles of Growth Hormone and IGF-1 in Insulin Resistance
Diabetes October 2003, Vol.52, 2483-2489. doi:https://doi.org/10.2337/diabetes.52.10.2483
Obesity Studies
Insulin Sensitivity, Insulin Secretion, and Abdominal Fat: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study
Lynne E. Wagenknecht; Carl D. Langefeld; Ann L. Scherzinger; Jill M. Norris; Steven M. Haffner; Mohammed F. Saad; Richard N. Bergman
Diabetes October 2003, Vol.52, 2490-2496. doi:https://doi.org/10.2337/diabetes.52.10.2490
Immunology and Transplantation
Variations in IB1/JIP1 Expression Regulate Susceptibility of β-Cells to Cytokine-Induced Apoptosis Irrespective of C-Jun NH2-Terminal Kinase Signaling
Zhidong Ling; Mark Van de Casteele; Jing Dong; Harry Heimberg; Jacques-Antoine Haefliger; Gérard Waeber; Frans Schuit; Daniel Pipeleers
Diabetes October 2003, Vol.52, 2497-2502. doi:https://doi.org/10.2337/diabetes.52.10.2497
Islet Studies
Nestin-Lineage Cells Contribute to the Microvasculature but Not Endocrine Cells of the Islet
Mary Kay Treutelaar; Jennifer M. Skidmore; Claudia L. Dias-Leme; Manami Hara; Lizhi Zhang; Diane Simeone; Donna M. Martin; Charles F. Burant
Diabetes October 2003, Vol.52, 2503-2512. doi:https://doi.org/10.2337/diabetes.52.10.2503
NN414, a SUR1/Kir6.2-Selective Potassium Channel Opener, Reduces Blood Glucose and Improves Glucose Tolerance in the VDF Zucker Rat
Diabetes October 2003, Vol.52, 2513-2518. doi:https://doi.org/10.2337/diabetes.52.10.2513
Characterization and Isolation of Promoter-Defined Nestin-Positive Cells from the Human Fetal Pancreas
Rohan K. Humphrey; Nathan Bucay; Gillian M. Beattie; Ana Lopez; Conrad A. Messam; Vincenzo Cirulli; Alberto Hayek
Diabetes October 2003, Vol.52, 2519-2525. doi:https://doi.org/10.2337/diabetes.52.10.2519
Sulfonylureas Rapidly Cross Phospholipid Bilayer Membranes by a Free-Diffusion Mechanism
Diabetes October 2003, Vol.52, 2526-2531. doi:https://doi.org/10.2337/diabetes.52.10.2526
Pathophysiology
Long-Term Improvement in Insulin Sensitivity by Changing Lifestyles of People with Impaired Glucose Tolerance: 4-Year Results From the Finnish Diabetes Prevention Study
Matti Uusitupa; Virpi Lindi; Anne Louheranta; Titta Salopuro; Jaana Lindström; Jaakko Tuomilehto; for the Finnish Diabetes Prevention Study Group
Diabetes October 2003, Vol.52, 2532-2538. doi:https://doi.org/10.2337/diabetes.52.10.2532
Cellular Aspects of Intestinal Lipoprotein Assembly in Psammomys Obesus: A Model of Insulin Resistance and Type 2 Diabetes
Monika Zoltowska; Ehud Ziv; Edgard Delvin; Daniel Sinnett; Ronny Kalman; Carole Garofalo; Ernest Seidman; Emile Levy
Diabetes October 2003, Vol.52, 2539-2545. doi:https://doi.org/10.2337/diabetes.52.10.2539
Low Plasma Ghrelin Is Associated With Insulin Resistance, Hypertension, and the Prevalence of Type 2 Diabetes
Seppo M. Pöykkö; Eija Kellokoski; Sohvi Hörkkö; Heikki Kauma; Y. Antero Kesäniemi; Olavi Ukkola
Diabetes October 2003, Vol.52, 2546-2553. doi:https://doi.org/10.2337/diabetes.52.10.2546
Complications
Insulin Affects Vascular Smooth Muscle Cell Phenotype and Migration Via Distinct Signaling Pathways
Diabetes October 2003, Vol.52, 2562-2569. doi:https://doi.org/10.2337/diabetes.52.10.2562
Reactive Oxygen Species from Mitochondria Induce Cyclooxygenase-2 Gene Expression in Human Mesangial Cells: Potential Role in Diabetic Nephropathy
Shinsuke Kiritoshi; Takeshi Nishikawa; Kazuhiro Sonoda; Daisuke Kukidome; Takahumi Senokuchi; Tomoko Matsuo; Takeshi Matsumura; Hiroshi Tokunaga; Michael Brownlee; Eiichi Araki
Diabetes October 2003, Vol.52, 2570-2577. doi:https://doi.org/10.2337/diabetes.52.10.2570
Neuroprotective Effect of Docosahexaenoic Acid-Enriched Phospholipids in Experimental Diabetic Neuropathy
Diabetes October 2003, Vol.52, 2578-2585. doi:https://doi.org/10.2337/diabetes.52.10.2578
Intercellular Adhesion Molecule-1–Deficient Mice Are Resistant Against Renal Injury After Induction of Diabetes
Shinichi Okada; Kenichi Shikata; Mitsuhiro Matsuda; Daisuke Ogawa; Hitomi Usui; Yuichi Kido; Ryo Nagase; Jun Wada; Yasushi Shikata; Hirofumi Makino
Diabetes October 2003, Vol.52, 2586-2593. doi:https://doi.org/10.2337/diabetes.52.10.2586
Glucose Induces Clonal Selection and Reversible Dinucleotide Repeat Expansion in Mesangial Cells Isolated from Glomerulosclerosis-Prone Mice
Diabetes October 2003, Vol.52, 2594-2602. doi:https://doi.org/10.2337/diabetes.52.10.2594
Translocation of Glomerular p47phox and p67phox by Protein Kinase C-β Activation Is Required for Oxidative Stress in Diabetic Nephropathy
Munehiro Kitada; Daisuke Koya; Toshiro Sugimoto; Motohide Isono; Shin-ichi Araki; Atsunori Kashiwagi; Masakazu Haneda
Diabetes October 2003, Vol.52, 2603-2614. doi:https://doi.org/10.2337/diabetes.52.10.2603
Endoneurial Capillary Abnormalities Presage Deterioration of Glucose Tolerance and Accompany Peripheral Neuropathy in Man
Soley Thrainsdottir; Rayez A. Malik; Lars B. Dahlin; Peter Wiksell; Karl F. Eriksson; Ingmar Rosén; Jesper Petersson; Douglas A. Greene; Göran Sundkvist
Diabetes October 2003, Vol.52, 2615-2622. doi:https://doi.org/10.2337/diabetes.52.10.2615
Relationship of Family History of Type 2 Diabetes, Hypoglycemia, and Autoantibodies to Weight Gain and Lipids With Intensive and Conventional Therapy in the Diabetes Control and Complications Trial
Jonathan Q. Purnell; Raj K. Dev; Michael W. Steffes; Patricia A. Cleary; Jerry P. Palmer; Irl B. Hirsch; John E. Hokanson; John D. Brunzell
Diabetes October 2003, Vol.52, 2623-2629. doi:https://doi.org/10.2337/diabetes.52.10.2623
Brief Genetics Reports
A Novel Gene for Neonatal Diabetes Maps to Chromosome 10p12.1-p13
Diabetes October 2003, Vol.52, 2636-2638. doi:https://doi.org/10.2337/diabetes.52.10.2636
KIR in Type 1 Diabetes : Disparate Distribution of Activating and Inhibitory Natural Killer Cell Receptors in Patients Versus HLA-Matched Control Subjects
Arno R. van der Slik; Bobby P.C. Koeleman; Willem Verduijn; G. Jan Bruining; Bart O. Roep; Marius J. Giphart
Diabetes October 2003, Vol.52, 2639-2642. doi:https://doi.org/10.2337/diabetes.52.10.2639
