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Issues
1 December 2003
ISSN 0012-1797
EISSN 1939-327X
Perspectives in Diabetes
Microvascular Complications of Impaired Glucose Tolerance
Diabetes December 2003, Vol.52, 2867-2873. doi:https://doi.org/10.2337/diabetes.52.12.2867
Metabolism
Endurance Training in Humans Leads to Fiber Type-Specific Increases in Levels of Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 and Peroxisome Proliferator-Activated Receptor-α in Skeletal Muscle
Aaron P. Russell; Jonas Feilchenfeldt; Sylvia Schreiber; Manu Praz; Antoinette Crettenand; Charles Gobelet; Christoph A. Meier; David R. Bell; Anastasia Kralli; Jean-Paul Giacobino; Olivier Dériaz
Diabetes December 2003, Vol.52, 2874-2881. doi:https://doi.org/10.2337/diabetes.52.12.2874
Elevation of Free Fatty Acids Induces Inflammation and Impairs Vascular Reactivity in Healthy Subjects
Devjit Tripathy; Priya Mohanty; Sandeep Dhindsa; Tufail Syed; Husam Ghanim; Ahmad Aljada; Paresh Dandona
Diabetes December 2003, Vol.52, 2882-2887. doi:https://doi.org/10.2337/diabetes.52.12.2882
A Mammalian Protein Homologous to Fructosamine-3-Kinase Is a Ketosamine-3-Kinase Acting on Psicosamines and Ribulosamines but not on Fructosamines
Diabetes December 2003, Vol.52, 2888-2895. doi:https://doi.org/10.2337/diabetes.52.12.2888
Signal Transduction
Oxidative Stress Induces Nucleo-Cytoplasmic Translocation of Pancreatic Transcription Factor PDX-1 Through Activation of c-Jun NH2-terminal Kinase
Dan Kawamori; Yoshitaka Kajimoto; Hideaki Kaneto; Yutaka Umayahara; Yoshio Fujitani; Takeshi Miyatsuka; Hirotaka Watada; Ingo B. Leibiger; Yoshimitsu Yamasaki; Masatsugu Hori
Diabetes December 2003, Vol.52, 2896-2904. doi:https://doi.org/10.2337/diabetes.52.12.2896
Hepatic Akt Activation Induces Marked Hypoglycemia, Hepatomegaly, and Hypertriglyceridemia With Sterol Regulatory Element Binding Protein Involvement
Hiraku Ono; Hitoshi Shimano; Hideki Katagiri; Naoya Yahagi; Hideyuki Sakoda; Yukiko Onishi; Motonobu Anai; Takehide Ogihara; Midori Fujishiro; Amelia Y.I. Viana; Yasushi Fukushima; Miho Abe; Nobuhiro Shojima; Masatoshi Kikuchi; Nobuhiro Yamada; Yoshitomo Oka; Tomoichiro Asano
Diabetes December 2003, Vol.52, 2905-2913. doi:https://doi.org/10.2337/diabetes.52.12.2905
Obesity Study
Agouti Expression in Human Adipose Tissue: Functional Consequences and Increased Expression in Type 2 Diabetes
Steven R. Smith; Barbara Gawronska-Kozak; Lenka Janderová; Taylor Nguyen; Angela Murrell; Jacqueline M. Stephens; Randall L. Mynatt
Diabetes December 2003, Vol.52, 2914-2922. doi:https://doi.org/10.2337/diabetes.52.12.2914
Insulin is Required for Prandial Ghrelin Suppression in Humans
Giuseppe Murdolo; Paola Lucidi; Chiara Di Loreto; Natascia Parlanti; Arianna De Cicco; Cristina Fatone; Carmine G. Fanelli; Geremia B. Bolli; Fausto Santeusanio; Pierpaolo De Feo
Diabetes December 2003, Vol.52, 2923-2927. doi:https://doi.org/10.2337/diabetes.52.12.2923
Adrenalectomy Alters the Sensitivity of the Central Nervous System Melanocortin System
Deborah L. Drazen; Matthew D. Wortman; Michael W. Schwartz; Deborah J. Clegg; Gertjan van Dijk; Stephen C. Woods; Randy J. Seeley
Diabetes December 2003, Vol.52, 2928-2934. doi:https://doi.org/10.2337/diabetes.52.12.2928
Immunology and Transplantation
Brain Death Significantly Reduces Isolated Pancreatic Islet Yields and Functionality In Vitro and In Vivo After Transplantation in Rats
Juan L. Contreras; Christopher Eckstein; Cheryl A. Smyth; Marty T. Sellers; Mario Vilatoba; Guadalupe Bilbao; Firoz G. Rahemtulla; Carlton J. Young; J. Anthony Thompson; Irshad H. Chaudry; Devin E. Eckhoff
Diabetes December 2003, Vol.52, 2935-2942. doi:https://doi.org/10.2337/diabetes.52.12.2935
Islet Study
On-Line Monitoring of Apoptosis in Insulin-Secreting Cells
Martin Köhler; Sergei V. Zaitsev; Irina I. Zaitseva; Barbara Leibiger; Ingo B. Leibiger; Mikael Turunen; Iouri L. Kapelioukh; Linda Bakkman; Ioulia B. Appelskog; Jacques Boutet de Monvel; Gabriela Imreh; Per-Olof Berggren
Diabetes December 2003, Vol.52, 2943-2950. doi:https://doi.org/10.2337/diabetes.52.12.2943
Pathophysiology
Gestational Diabetes Induces Placental Genes for Chronic Stress and Inflammatory Pathways
Diabetes December 2003, Vol.52, 2951-2958. doi:https://doi.org/10.2337/diabetes.52.12.2951
Complications
Nephrinuria in Diabetic Nephropathy of Type 1 Diabetes
Anu Pätäri; Carol Forsblom; Marika Havana; Heidi Taipale; Per-Henrik Groop; Harry Holthöfer; the FinnDiane Study Group
Diabetes December 2003, Vol.52, 2969-2974. doi:https://doi.org/10.2337/diabetes.52.12.2969
Connective Tissue Growth Factor and IGF-I Are Produced by Human Renal Fibroblasts and Cooperate in the Induction of Collagen Production by High Glucose
Suzanne Lam; Reinier N. van der Geest; Nicole A.M. Verhagen; Frans A. van Nieuwenhoven; Ingrid E. Blom; Jan Aten; Roel Goldschmeding; Mohamed R. Daha; Cees van Kooten
Diabetes December 2003, Vol.52, 2975-2983. doi:https://doi.org/10.2337/diabetes.52.12.2975
Genetics
Regulation of Apolipoprotein M Gene Expression by MODY3 Gene Hepatocyte Nuclear Factor-1α: Haploinsufficiency Is Associated With Reduced Serum Apolipoprotein M Levels
Symi Richter; David Q. Shih; Ewan R. Pearson; Christian Wolfrum; Stefan S. Fajans; Andrew T. Hattersley; Markus Stoffel
Diabetes December 2003, Vol.52, 2989-2995. doi:https://doi.org/10.2337/diabetes.52.12.2989
Brief Genetics Report
The Human MC4R Promoter: Characterization and Role in Obesity
Cecile Lubrano-Berthelier; Martha Cavazos; Catherine Le Stunff; Kurt Haas; Astrid Shapiro; Sumei Zhang; Pierre Bougneres; Christian Vaisse
Diabetes December 2003, Vol.52, 2996-3000. doi:https://doi.org/10.2337/diabetes.52.12.2996
A Genome-Wide Search for Genes Involved in Type 2 Diabetes in a Recently Genetically Isolated Population From the Netherlands
Yurii S. Aulchenko; Norbert Vaessen; Peter Heutink; Jan Pullen; Pieter J.L.M. Snijders; Albert Hofman; Lodewijk A. Sandkuijl; Jeanine J. Houwing-Duistermaat; Mark Edwards; Simon Bennett; Ben A. Oostra; Cornelia M. van Duijn
Diabetes December 2003, Vol.52, 3001-3004. doi:https://doi.org/10.2337/diabetes.52.12.3001
The Role of Insulin Receptor Substrate-1 Gene (IRS1) in Type 2 Diabetes in Pima Indians
Peter Kovacs; Robert L. Hanson; Yong-Ho Lee; Xiaolin Yang; Sayuko Kobes; Paska A. Permana; Clifton Bogardus; Leslie J. Baier
Diabetes December 2003, Vol.52, 3005-3009. doi:https://doi.org/10.2337/diabetes.52.12.3005