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Rapid Publications

Insulin Activation of Phosphatidylinositol 3-Kinase in the Hypothalamic Arcuate Nucleus: A Key Mediator of Insulin-Induced Anorexia

Kevin D. Niswender; Christopher D. Morrison; Deborah J. Clegg; Ryan Olson; Denis G. Baskin; Martin G. Myers, Jr.; Randy J. Seeley; Michael W. Schwartz

Abstracts

View articletitled, Insulin Activation of Phosphatidylinositol 3-Kinase in the Hypothalamic Arcuate Nucleus: A Key Mediator of Insulin-Induced Anorexia

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Diabetes February 2003, Vol.52, 227-231. doi:https://doi.org/10.2337/diabetes.52.2.227

Perspectives in Diabetes

Is the Energy Homeostasis System Inherently Biased Toward Weight Gain?

Michael W. Schwartz; Stephen C. Woods; Randy J. Seeley; Gregory S. Barsh; Denis G. Baskin; Rudolph L. Leibel

Abstracts

View articletitled, Is the Energy Homeostasis System Inherently Biased Toward Weight Gain?

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Diabetes February 2003, Vol.52, 232-238. doi:https://doi.org/10.2337/diabetes.52.2.232

Metabolism and Signal Transduction

Plasma Adiponectin Concentrations Predict Insulin Sensitivity of Both Glucose and Lipid Metabolism

Otto Tschritter; Andreas Fritsche; Claus Thamer; Michael Haap; Fatemeh Shirkavand; Stefanie Rahe; Harald Staiger; Elke Maerker; Hans Häring; Michael Stumvoll

Abstracts

View articletitled, Plasma Adiponectin Concentrations Predict Insulin Sensitivity of Both Glucose and Lipid Metabolism

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Diabetes February 2003, Vol.52, 239-243. doi:https://doi.org/10.2337/diabetes.52.2.239

Increased Intramyocellular Lipid Concentration Identifies Impaired Glucose Metabolism in Women With Previous Gestational Diabetes

Alexandra Kautzky-Willer; Martin Krssak; Christine Winzer; Giovanni Pacini; Andrea Tura; Serdar Farhan; Oswald Wagner; Georg Brabant; Rüdiger Horn; Harald Stingl; Barbara Schneider; Werner Waldhäusl; Michael Roden

Abstracts

View articletitled, Increased Intramyocellular Lipid Concentration Identifies Impaired Glucose Metabolism in Women With Previous Gestational Diabetes

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Diabetes February 2003, Vol.52, 244-251. doi:https://doi.org/10.2337/diabetes.52.2.244

Role of Leptin in the Regulation of Glucagon-Like Peptide-1 Secretion

Younes Anini; Patricia L. Brubaker

Abstracts

View articletitled, Role of Leptin in the Regulation of Glucagon-Like Peptide-1 Secretion

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Diabetes February 2003, Vol.52, 252-259. doi:https://doi.org/10.2337/diabetes.52.2.252

Effects of Free Fatty Acids Per Se on Glucose Production, Gluconeogenesis, and Glycogenolysis

Peter Staehr; Ole Hother-Nielsen; Bernard R. Landau; Visvanathan Chandramouli; Jens Juul Holst; Henning Beck-Nielsen

Abstracts

View articletitled, Effects of Free Fatty Acids Per Se on Glucose Production, Gluconeogenesis, and Glycogenolysis

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Diabetes February 2003, Vol.52, 260-267. doi:https://doi.org/10.2337/diabetes.52.2.260

Obesity Studies

Sexual Differentiation, Pregnancy, Calorie Restriction, and Aging Affect the Adipocyte-Specific Secretory Protein Adiponectin

Terry P. Combs; Anders H. Berg; Michael W. Rajala; Simon Klebanov; Puneeth Iyengar; José C. Jimenez-Chillaron; Mary Elizabeth Patti; Sabra L. Klein; Robert S. Weinstein; Philipp E. Scherer

Abstracts

View articletitled, Sexual Differentiation, Pregnancy, Calorie Restriction, and Aging Affect the Adipocyte-Specific Secretory Protein Adiponectin

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Diabetes February 2003, Vol.52, 268-276. doi:https://doi.org/10.2337/diabetes.52.2.268

Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose

Marc Gilbert; Christophe Magnan; Sophie Turban; Jocelyne André; Michèle Guerre-Millo

Abstracts

View articletitled, Leptin Receptor−Deficient Obese Zucker Rats Reduce Their Food Intake in Response to a Systemic Supply of Calories From Glucose

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Diabetes February 2003, Vol.52, 277-282. doi:https://doi.org/10.2337/diabetes.52.2.277

Differential Effects of Rosiglitazone and Metformin on Adipose Tissue Distribution and Glucose Uptake in Type 2 Diabetic Subjects

Kirsi A. Virtanen; Kirsti Hällsten; Riitta Parkkola; Tuula Janatuinen; Fredrik Lönnqvist; Tapio Viljanen; Tapani Rönnemaa; Juhani Knuuti; Risto Huupponen; Peter Lönnroth; Pirjo Nuutila

Abstracts

View articletitled, Differential Effects of Rosiglitazone and Metformin on Adipose Tissue Distribution and Glucose Uptake in Type 2 Diabetic Subjects

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Diabetes February 2003, Vol.52, 283-290. doi:https://doi.org/10.2337/diabetes.52.2.283

PPAR-γ Activation Mediates Adipose Depot−Specific Effects on Gene Expression and Lipoprotein Lipase Activity: Mechanisms for Modulation of Postprandial Lipemia and Differential Adipose Accretion

Mathieu Laplante; Henrike Sell; Karen L. MacNaul; Denis Richard; Joel P. Berger; Yves Deshaies

Abstracts

View articletitled, PPAR-γ Activation Mediates Adipose Depot−Specific Effects on Gene Expression and Lipoprotein Lipase Activity: Mechanisms for Modulation of Postprandial Lipemia and Differential Adipose Accretion

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Diabetes February 2003, Vol.52, 291-299. doi:https://doi.org/10.2337/diabetes.52.2.291

Role of the Fatty Acid Binding Protein mal1 in Obesity and Insulin Resistance

Kazuhisa Maeda; K. Teoman Uysal; Liza Makowski; Cem Z. Görgün; Genichi Atsumi; Rex A. Parker; Jens Brüning; Ann Vogel Hertzel; David A. Bernlohr; Gökhan S. Hotamisligil

Abstracts

View articletitled, Role of the Fatty Acid Binding Protein mal1 in Obesity and Insulin Resistance

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Diabetes February 2003, Vol.52, 300-307. doi:https://doi.org/10.2337/diabetes.52.2.300

STAT5A Promotes Adipogenesis in Nonprecursor Cells and Associates With the Glucocorticoid Receptor During Adipocyte Differentiation

Z. Elizabeth Floyd; Jacqueline M. Stephens

Abstracts

View articletitled, STAT5A Promotes Adipogenesis in Nonprecursor Cells and Associates With the Glucocorticoid Receptor During Adipocyte Differentiation

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Diabetes February 2003, Vol.52, 308-314. doi:https://doi.org/10.2337/diabetes.52.2.308

Hyperactivity and Reduced Energy Cost of Physical Activity in Serotonin 5-HT_2C Receptor Mutant Mice

Katsunori Nonogaki; Luna Abdallah; Evan H. Goulding; Stephen J. Bonasera; Laurence H. Tecott

Abstracts

View articletitled, Hyperactivity and Reduced Energy Cost of Physical Activity in Serotonin 5-HT2C Receptor Mutant Mice

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Diabetes February 2003, Vol.52, 315-320. doi:https://doi.org/10.2337/diabetes.52.2.315

Immunology and Transplantation

NOD Congenic Mice Genetically Protected From Autoimmune Diabetes Remain Resistant to Transplantation Tolerance Induction

Todd Pearson; Thomas G. Markees; Linda S. Wicker; David V. Serreze; Laurence B. Peterson; John P. Mordes; Aldo A. Rossini; Dale L. Greiner

Abstracts

View articletitled, NOD Congenic Mice Genetically Protected From Autoimmune Diabetes Remain Resistant to Transplantation Tolerance Induction

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Diabetes February 2003, Vol.52, 321-326. doi:https://doi.org/10.2337/diabetes.52.2.321

T-Cell Compartments of Prediabetic NOD Mice

Stuart P. Berzins; Emily S. Venanzi; Christophe Benoist; Diane Mathis

Abstracts

View articletitled, T-Cell Compartments of Prediabetic NOD Mice

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Diabetes February 2003, Vol.52, 327-334. doi:https://doi.org/10.2337/diabetes.52.2.327

Acute Shock Induced by Antigen Vaccination in NOD Mice

Lut Overbergh; Brigitte Decallonne; Dumitru D. Branisteanu; Dirk Valckx; Ahmad Kasran; Roger Bouillon; Chantal Mathieu

Abstracts

View articletitled, Acute Shock Induced by Antigen Vaccination in NOD Mice

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Diabetes February 2003, Vol.52, 335-341. doi:https://doi.org/10.2337/diabetes.52.2.335

Accelerated Diabetes in Rat Insulin Promoter-Tumor Necrosis Factor-α Transgenic Nonobese Diabetic Mice Lacking Major Histocompatibility Class II Molecules

Govindarajan Rajagopalan; Yogish C. Kudva; Richard A. Flavell; Chella S. David

Abstracts

View articletitled, Accelerated Diabetes in Rat Insulin Promoter-Tumor Necrosis Factor-α Transgenic Nonobese Diabetic Mice Lacking Major Histocompatibility Class II Molecules

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Diabetes February 2003, Vol.52, 342-347. doi:https://doi.org/10.2337/diabetes.52.2.342

Molecular Regulation of Monocyte Chemoattractant Protein-1 Expression in Pancreatic β-Cells

Burak Kutlu; Martine I. Darville; Alessandra K. Cardozo; Décio L. Eizirik

Abstracts

View articletitled, Molecular Regulation of Monocyte Chemoattractant Protein-1 Expression in Pancreatic β-Cells

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Diabetes February 2003, Vol.52, 348-355. doi:https://doi.org/10.2337/diabetes.52.2.348

Islet Studies

Stimulation of Insulin Secretion by Denatonium, One of the Most Bitter-Tasting Substances Known

Susanne G. Straub; Jennifer Mulvaney-Musa; Hiroki Yajima; Gregory A. Weiland; Geoffrey W.G. Sharp

Abstracts

View articletitled, Stimulation of Insulin Secretion by Denatonium, One of the Most Bitter-Tasting Substances Known

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Diabetes February 2003, Vol.52, 356-364. doi:https://doi.org/10.2337/diabetes.52.2.356

Role of Endogenous Glucagon-Like Peptide-1 in Islet Regeneration After Partial Pancreatectomy

Diva D. De León; Shaoping Deng; Reza Madani; Rexford S. Ahima; Daniel J. Drucker; Doris A. Stoffers

Abstracts

View articletitled, Role of Endogenous Glucagon-Like Peptide-1 in Islet Regeneration After Partial Pancreatectomy

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Diabetes February 2003, Vol.52, 365-371. doi:https://doi.org/10.2337/diabetes.52.2.365

Increased Dietary Fat Promotes Islet Amyloid Formation and β-Cell Secretory Dysfunction in a Transgenic Mouse Model of Islet Amyloid

Rebecca L. Hull; Sofianos Andrikopoulos; C. Bruce Verchere; Josep Vidal; Feng Wang; Miriam Cnop; Ronald L. Prigeon; Steven E. Kahn

Abstracts

View articletitled, Increased Dietary Fat Promotes Islet Amyloid Formation and β-Cell Secretory Dysfunction in a Transgenic Mouse Model of Islet Amyloid

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Diabetes February 2003, Vol.52, 372-379. doi:https://doi.org/10.2337/diabetes.52.2.372

The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on β-Cell Sensitivity in Type 2 and Nondiabetic Subjects

Lise L. Kjems; Jens J. Holst; Aage Vølund; Sten Madsbad

Abstracts

View articletitled, The Influence of GLP-1 on Glucose-Stimulated Insulin Secretion: Effects on β-Cell Sensitivity in Type 2 and Nondiabetic Subjects

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Diabetes February 2003, Vol.52, 380-386. doi:https://doi.org/10.2337/diabetes.52.2.380

Gene Transfer of Manganese Superoxide Dismutase Extends Islet Graft Function in a Mouse Model of Autoimmune Diabetes

Suzanne Bertera; Megan L. Crawford; Angela M. Alexander; Glenn D. Papworth; Simon C. Watkins; Paul D. Robbins; Massimo Trucco

Abstracts

View articletitled, Gene Transfer of Manganese Superoxide Dismutase Extends Islet Graft Function in a Mouse Model of Autoimmune Diabetes

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Diabetes February 2003, Vol.52, 387-393. doi:https://doi.org/10.2337/diabetes.52.2.387

Differential Effects of Glucose and Glyburide on Energetics and Na⁺ Levels of βHC9 Cells: Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies

Nicolai M. Doliba; Marko Z. Vatamaniuk; Carol W. Buettger; Wei Qin; Heather W. Collins; Suzanne L. Wehrli; Richard D. Carr; Franz M. Matschinsky

Abstracts

View articletitled, Differential Effects of Glucose and Glyburide on Energetics and Na+ Levels of βHC9 Cells: Nuclear Magnetic Resonance Spectroscopy and Respirometry Studies

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Diabetes February 2003, Vol.52, 394-402. doi:https://doi.org/10.2337/diabetes.52.2.394

BETA2 Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells

J. Michael Moates; Sarmistha Nanda; Michelle A. Cissell; Ming-Jer Tsai; Roland Stein

Abstracts

View articletitled, BETA2 Activates Transcription From the Upstream Glucokinase Gene Promoter in Islet β-Cells and Gut Endocrine Cells

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Diabetes February 2003, Vol.52, 403-408. doi:https://doi.org/10.2337/diabetes.52.2.403

Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse

Tetsuro Izumi; Hiromi Yokota-Hashimoto; Shengli Zhao; Jie Wang; Philippe A. Halban; Toshiyuki Takeuchi

Abstracts

View articletitled, Dominant Negative Pathogenesis by Mutant Proinsulin in the Akita Diabetic Mouse

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Diabetes February 2003, Vol.52, 409-416. doi:https://doi.org/10.2337/diabetes.52.2.409

Connexin 36 Controls Synchronization of Ca²⁺ Oscillations and Insulin Secretion in MIN6 Cells

Alessandra Calabrese; Min Zhang; Véronique Serre-Beinier; David Caton; Christophe Mas; Leslie S. Satin; Paolo Meda

Abstracts

View articletitled, Connexin 36 Controls Synchronization of Ca2+ Oscillations and Insulin Secretion in MIN6 Cells

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Diabetes February 2003, Vol.52, 417-424. doi:https://doi.org/10.2337/diabetes.52.2.417

Pax-6 Activates Endogenous Proglucagon Gene Expression in the Rodent Gastrointestinal Epithelium

Denny K.Y. Trinh; Kai Zhang; Moazzem Hossain; Patricia L. Brubaker; Daniel J. Drucker

Abstracts

View articletitled, Pax-6 Activates Endogenous Proglucagon Gene Expression in the Rodent Gastrointestinal Epithelium

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Diabetes February 2003, Vol.52, 425-433. doi:https://doi.org/10.2337/diabetes.52.2.425

Pathophysiology

Age-Dependent Changes in Metabolism, Contractile Function, and Ischemic Sensitivity in Hearts From db/db Mice

Ellen Aasum; Anne D. Hafstad; David L. Severson; Terje S. Larsen

Abstracts

View articletitled, Age-Dependent Changes in Metabolism, Contractile Function, and Ischemic Sensitivity in Hearts From db/db Mice

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Diabetes February 2003, Vol.52, 434-441. doi:https://doi.org/10.2337/diabetes.52.2.434

Inflammation-Sensitive Plasma Proteins, Diabetes, and Mortality and Incidence of Myocardial Infarction and Stroke: A Population-Based Study

Gunnar Engström; Lars Stavenow; Bo Hedblad; Peter Lind; Karl-Fredrik Eriksson; Lars Janzon; Folke Lindgärde

Abstracts

View articletitled, Inflammation-Sensitive Plasma Proteins, Diabetes, and Mortality and Incidence of Myocardial Infarction and Stroke: A Population-Based Study

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Diabetes February 2003, Vol.52, 442-447. doi:https://doi.org/10.2337/diabetes.52.2.442

Preferential Stiffening of Central Over Peripheral Arteries in Type 2 Diabetes

Eiji Kimoto; Tetsuo Shoji; Kayo Shinohara; Masaaki Inaba; Yasuhisa Okuno; Takami Miki; Hidenori Koyama; Masanori Emoto; Yoshiki Nishizawa

Abstracts

View articletitled, Preferential Stiffening of Central Over Peripheral Arteries in Type 2 Diabetes

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Diabetes February 2003, Vol.52, 448-452. doi:https://doi.org/10.2337/diabetes.52.2.448

Effects of Insulin Resistance and Type 2 Diabetes on Lipoprotein Subclass Particle Size and Concentration Determined by Nuclear Magnetic Resonance

W. Timothy Garvey; Soonho Kwon; Deyi Zheng; Sara Shaughnessy; Penny Wallace; Amy Hutto; Kimberly Pugh; Alicia J. Jenkins; Richard L. Klein; Youlian Liao

Abstracts

View articletitled, Effects of Insulin Resistance and Type 2 Diabetes on Lipoprotein Subclass Particle Size and Concentration Determined by Nuclear Magnetic Resonance

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Diabetes February 2003, Vol.52, 453-462. doi:https://doi.org/10.2337/diabetes.52.2.453

Prediction of Type 2 Diabetes Using Simple Measures of Insulin Resistance: Combined Results From the San Antonio Heart Study, the Mexico City Diabetes Study, and the Insulin Resistance Atherosclerosis Study

Anthony J.G. Hanley; Ken Williams; Clicerio Gonzalez; Ralph B. D’Agostino, Jr; Lynne E. Wagenknecht; Michael P. Stern; Steven M. Haffner

Abstracts

View articletitled, Prediction of Type 2 Diabetes Using Simple Measures of Insulin Resistance: Combined Results From the San Antonio Heart Study, the Mexico City Diabetes Study, and the Insulin Resistance Atherosclerosis Study

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Diabetes February 2003, Vol.52, 463-469. doi:https://doi.org/10.2337/diabetes.52.2.463

Altered Homeostatic Adaptation of First- and Second-Phase β-Cell Secretion in the Offspring of Patients With Type 2 Diabetes: Studies With a Minimal Model to Assess β-Cell Function

Riccardo C. Bonadonna; Michael Stumvoll; Andreas Fritsche; Michele Muggeo; Hans Häring; Enzo Bonora; Timon W. van Haeften

Abstracts

View articletitled, Altered Homeostatic Adaptation of First- and Second-Phase β-Cell Secretion in the Offspring of Patients With Type 2 Diabetes: Studies With a Minimal Model to Assess β-Cell Function

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Diabetes February 2003, Vol.52, 470-480. doi:https://doi.org/10.2337/diabetes.52.2.470

Diabetes Activates Cell Death Pathway After Transient Focal Cerebral Ischemia

Marianna Muranyi; Masayuki Fujioka; QingPing He; Angela Han; Gregory Yong; Katalin Csiszar; Ping-An Li

Abstracts

View articletitled, Diabetes Activates Cell Death Pathway After Transient Focal Cerebral Ischemia

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Diabetes February 2003, Vol.52, 481-486. doi:https://doi.org/10.2337/diabetes.52.2.481

Effects of Free Fatty Acids on Glucose Uptake and Utilization in Healthy Women

Carol J. Homko; Peter Cheung; Guenther Boden

Abstracts

View articletitled, Effects of Free Fatty Acids on Glucose Uptake and Utilization in Healthy Women

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Diabetes February 2003, Vol.52, 487-491. doi:https://doi.org/10.2337/diabetes.52.2.487

Demonstration of Glycated Insulin in Human Diabetic Plasma and Decreased Biological Activity Assessed by Euglycemic-Hyperinsulinemic Clamp Technique in Humans

Steven J. Hunter; Alison C. Boyd; Finbarr P.M. O’Harte; Aine M. McKillop; M. Ivan Wiggam; Mark H. Mooney; Jane T. McCluskey; John R. Lindsay; Cieran N. Ennis; Raymond Gamble; Brian Sheridan; Christopher R. Barnett; Helene McNulty; Patrick M. Bell; Peter R. Flatt

Abstracts

View articletitled, Demonstration of Glycated Insulin in Human Diabetic Plasma and Decreased Biological Activity Assessed by Euglycemic-Hyperinsulinemic Clamp Technique in Humans

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Diabetes February 2003, Vol.52, 492-498. doi:https://doi.org/10.2337/diabetes.52.2.492

Complications

Comparative Trial of N-Acetyl-Cysteine, Taurine, and Oxerutin on Skin and Kidney Damage in Long-Term Experimental Diabetes

Patrizio Odetti; Carlo Pesce; Nicola Traverso; Stefano Menini; Elena Pesce Maineri; Luana Cosso; Sabina Valentini; Stefania Patriarca; Damiano Cottalasso; Umberto M. Marinari; Maria Adelaide Pronzato

Abstracts

View articletitled, Comparative Trial of N-Acetyl-Cysteine, Taurine, and Oxerutin on Skin and Kidney Damage in Long-Term Experimental Diabetes

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Diabetes February 2003, Vol.52, 499-505. doi:https://doi.org/10.2337/diabetes.52.2.499

A Role for the Polyol Pathway in the Early Neuroretinal Apoptosis and Glial Changes Induced by Diabetes in the Rat

Veronica Asnaghi; Chiara Gerhardinger; Todd Hoehn; Abidemi Adeboje; Mara Lorenzi

Abstracts

View articletitled, A Role for the Polyol Pathway in the Early Neuroretinal Apoptosis and Glial Changes Induced by Diabetes in the Rat

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Diabetes February 2003, Vol.52, 506-511. doi:https://doi.org/10.2337/diabetes.52.2.506

Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension

Darren J. Kelly; Yuan Zhang; Claire Hepper; Renae M. Gow; Kassie Jaworski; Bruce E. Kemp; Jennifer L. Wilkinson-Berka; Richard E. Gilbert

Abstracts

View articletitled, Protein Kinase C β Inhibition Attenuates the Progression of Experimental Diabetic Nephropathy in the Presence of Continued Hypertension

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Diabetes February 2003, Vol.52, 512-518. doi:https://doi.org/10.2337/diabetes.52.2.512

Glucose-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase-Dependent Upregulation of the Platelet-Derived Growth Factor-β Receptor Potentiates Vascular Smooth Muscle Cell Chemotaxis

Malcolm Campbell; William E. Allen; Jonathan A. Silversides; Elisabeth R. Trimble

Abstracts

View articletitled, Glucose-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase-Dependent Upregulation of the Platelet-Derived Growth Factor-β Receptor Potentiates Vascular Smooth Muscle Cell Chemotaxis

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Diabetes February 2003, Vol.52, 519-526. doi:https://doi.org/10.2337/diabetes.52.2.519

Evidence for a Novel TGF-β1−Independent Mechanism of Fibronectin Production in Mesangial Cells Overexpressing Glucose Transporters

Cora Weigert; Katrin Brodbeck; Frank C. Brosius III; Matthias Huber; Rainer Lehmann; Ulrich Friess; Sonia Facchin; Steffen Aulwurm; Hans U. Häring; Erwin D. Schleicher; Charles W. Heilig

Abstracts

View articletitled, Evidence for a Novel TGF-β1−Independent Mechanism of Fibronectin Production in Mesangial Cells Overexpressing Glucose Transporters

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Diabetes February 2003, Vol.52, 527-535. doi:https://doi.org/10.2337/diabetes.52.2.527

Amelioration of Sensory Nerve Dysfunction by C-Peptide in Patients With Type 1 Diabetes

Karin Ekberg; Tom Brismar; Bo-Lennart Johansson; Björn Jonsson; Per Lindström; John Wahren

Abstracts

View articletitled, Amelioration of Sensory Nerve Dysfunction by C-Peptide in Patients With Type 1 Diabetes

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Diabetes February 2003, Vol.52, 536-541. doi:https://doi.org/10.2337/diabetes.52.2.536

Microvascular Alterations in Diabetic Mice Correlate With Level of Hyperglycemia

Petra Algenstaedt; Christian Schaefer; Tanja Biermann; Andreas Hamann; Britta Schwarzloh; Heiner Greten; Wolfgang Rüther; Nils Hansen-Algenstaedt

Abstracts

View articletitled, Microvascular Alterations in Diabetic Mice Correlate With Level of Hyperglycemia

Supplementary data

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Diabetes February 2003, Vol.52, 542-549. doi:https://doi.org/10.2337/diabetes.52.2.542

Genetics

Genome-Wide and Fine-Mapping Linkage Studies of Type 2 Diabetes and Glucose Traits in the Old Order Amish: Evidence for a New Diabetes Locus on Chromosome 14q11 and Confirmation of a Locus on Chromosome 1q21-q24

Wen-Chi Hsueh; Pamela L. St. Jean; Braxton D. Mitchell; Toni I. Pollin; William C. Knowler; Margaret G. Ehm; Callum J. Bell; Hakan Sakul; Michael J. Wagner; Daniel K. Burns; Alan R. Shuldiner

Abstracts

View articletitled, Genome-Wide and Fine-Mapping Linkage Studies of Type 2 Diabetes and Glucose Traits in the Old Order Amish: Evidence for a New Diabetes Locus on Chromosome 14q11 and Confirmation of a Locus on Chromosome 1q21-q24

Supplementary data

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Diabetes February 2003, Vol.52, 550-557. doi:https://doi.org/10.2337/diabetes.52.2.550

Brief Genetics Reports

The C-174G Promoter Polymorphism of the IL-6 Gene Affects Energy Expenditure and Insulin Sensitivity

Agata Kubaszek; Jussi Pihlajamäki; Kari Punnonen; Pauli Karhapää; Ilkka Vauhkonen; Markku Laakso

Abstracts

View articletitled, The C-174G Promoter Polymorphism of the IL-6 Gene Affects Energy Expenditure and Insulin Sensitivity

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Diabetes February 2003, Vol.52, 558-561. doi:https://doi.org/10.2337/diabetes.52.2.558

Systematic Search for Single Nucleotide Polymorphisms in the FOXC2 Gene: The Absence of Evidence for the Association of Three Frequent Single Nucleotide Polymorphisms and Four Common Haplotypes With Japanese Type 2 Diabetes

Haruhiko Osawa; Hiroshi Onuma; Akiko Murakami; Masaaki Ochi; Tatsuya Nishimiya; Kenichi Kato; Ikki Shimizu; Yasuhisa Fujii; Jun Ohashi; Hideichi Makino

Abstracts

View articletitled, Systematic Search for Single Nucleotide Polymorphisms in the FOXC2 Gene: The Absence of Evidence for the Association of Three Frequent Single Nucleotide Polymorphisms and Four Common Haplotypes With Japanese Type 2 Diabetes

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Diabetes February 2003, Vol.52, 562-567. doi:https://doi.org/10.2337/diabetes.52.2.562

Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell K_ATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

Anna L. Gloyn; Michael N. Weedon; Katharine R. Owen; Martina J. Turner; Bridget A. Knight; Graham Hitman; Mark Walker; Jonathan C. Levy; Mike Sampson; Stephanie Halford; Mark I. McCarthy; Andrew T. Hattersley; Timothy M. Frayling

Abstracts

View articletitled, Large-Scale Association Studies of Variants in Genes Encoding the Pancreatic β-Cell KATP Channel Subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) Confirm That the KCNJ11 E23K Variant Is Associated With Type 2 Diabetes

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Diabetes February 2003, Vol.52, 568-572. doi:https://doi.org/10.2337/diabetes.52.2.568

The E23K Variant of Kir6.2 Associates With Impaired Post-OGTT Serum Insulin Response and Increased Risk of Type 2 Diabetes

Eva-Maria D. Nielsen; Lars Hansen; Bendix Carstensen; Søren M. Echwald; Thomas Drivsholm; Charlotte Glümer; Birger Thorsteinsson; Knut Borch-Johnsen; Torben Hansen; Oluf Pedersen

Abstracts

View articletitled, The E23K Variant of Kir6.2 Associates With Impaired Post-OGTT Serum Insulin Response and Increased Risk of Type 2 Diabetes

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Diabetes February 2003, Vol.52, 573-577. doi:https://doi.org/10.2337/diabetes.52.2.573

Erratum

Errata

Extract

View articletitled, Errata

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Diabetes February 2003, Vol.52, 578. doi:https://doi.org/10.2337/diabetes.52.2.578

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